HOMER3 (NM_001145722) Human Mass Spec Standard

CAT#: PH326668

HOMER3 MS Standard C13 and N15-labeled recombinant protein (NP_001139194)



  View other "HOMER3" proteins (13)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of homer homolog 3 (Drosophila) (HOMER3), transcript variant 2
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Specifications

Product Data
Description HOMER3 MS Standard C13 and N15-labeled recombinant protein (NP_001139194)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226668
Predicted MW 39.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001139194
RefSeq Size 1859
RefSeq ORF 1083
Synonyms HOMER-3; VESL3
Locus ID 9454
Cytogenetics 19p13.11
Summary This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
Protein Families Druggable Genome
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