alpha 1 Antitrypsin (SERPINA1) (NM_001127701) Human Mass Spec Standard

CAT#: PH325656

SERPINA1 MS Standard C13 and N15-labeled recombinant protein (NP_001121173)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description SERPINA1 MS Standard C13 and N15-labeled recombinant protein (NP_001121173)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225656
Predicted MW 46.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001121173
RefSeq Size 3532
RefSeq ORF 1254
Synonyms A1A; A1AT; AAT; alpha1AT; nNIF; PI; PI1; PRO2275
Locus ID 5265
Cytogenetics 14q32.13
Summary The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Complement and coagulation cascades
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