CLDN19 (NM_001123395) Human Mass Spec Standard

CAT#: PH325251

CLDN19 MS Standard C13 and N15-labeled recombinant protein (NP_001116867)



  View other "CLDN19" proteins (7)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description CLDN19 MS Standard C13 and N15-labeled recombinant protein (NP_001116867)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225251
Predicted MW 21.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001116867
RefSeq ORF 633
Synonyms HOMG5
Locus ID 149461
Cytogenetics 1p34.2
Summary The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
Protein Families Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
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