Cathepsin L (CTSL) (NM_145918) Human Mass Spec Standard

CAT#: PH323541

CTSL1 MS Standard C13 and N15-labeled recombinant protein (NP_666023)



  View other "Cathepsin L" proteins (8)

Need it in bulk or customized?
Get a free quote

CNY 19,520.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (2)
Transient overexpression lysate of cathepsin L1 (CTSL1), transcript variant 2
    • 100 ug

CNY 3,080.00


CTSL1 mouse monoclonal antibody,clone OTI2H2
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Description CTSL1 MS Standard C13 and N15-labeled recombinant protein (NP_666023)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223541
Predicted MW 37.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_666023
RefSeq Size 1587
RefSeq ORF 999
Synonyms CATL; CTSL1; MEP
Locus ID 1514
Cytogenetics 9q21.33
Summary The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell. [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome, Protease
Protein Pathways Antigen processing and presentation, Lysosome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...