DEP1 (PTPRJ) (NM_002843) Human Mass Spec Standard

CAT#: PH322707

PTPRJ MS Standard C13 and N15-labeled recombinant protein (NP_002834)



  View other "DEP1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 1
    • 100 ug

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Rabbit polyclonal His6-DEP-1 Antibody
    • 400 ul

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Specifications

Product Data
Description PTPRJ MS Standard C13 and N15-labeled recombinant protein (NP_002834)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222707
Predicted MW 145.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002834
RefSeq Size 5119
RefSeq ORF 4011
Synonyms CD148; DEP1; HPTPeta; R-PTP-ETA; SCC1
Locus ID 5795
Cytogenetics 11p11.2
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Phosphatase, Transmembrane
Protein Pathways Adherens junction
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