TrkB (NTRK2) (NM_006180) Human Mass Spec Standard

CAT#: PH321794

NTRK2 MS Standard C13 and N15-labeled recombinant protein (NP_006171)



  View other "TrkB" proteins (16)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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    • 100 ul

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Specifications

Product Data
Description NTRK2 MS Standard C13 and N15-labeled recombinant protein (NP_006171)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221794
Predicted MW 93.83 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_006171
RefSeq Size 5608
RefSeq ORF 2514
Synonyms DEE58; EIEE58; GP145-TrkB; OBHD; trk-B; TRKB
Locus ID 4915
Cytogenetics 9q21.33
Summary This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways MAPK signaling pathway, Neurotrophin signaling pathway
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