Aurora A (AURKA) (NM_198436) Human Mass Spec Standard

CAT#: PH306572

AURKA MS Standard C13 and N15-labeled recombinant protein (NP_940838)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of aurora kinase A (AURKA), transcript variant 1
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Specifications

Product Data
Description AURKA MS Standard C13 and N15-labeled recombinant protein (NP_940838)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206572
Predicted MW 45.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_940838
RefSeq Size 2231
RefSeq ORF 1209
Synonyms AIK; ARK1; AURA; BTAK; PPP1R47; STK6; STK7; STK15
Locus ID 6790
Cytogenetics 20q13.2
Summary The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Protein Pathways Oocyte meiosis
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