Ribonuclease H2, subunit A (RNASEH2A) (NM_006397) Human Mass Spec Standard

CAT#: PH304032

RNASEH2A MS Standard C13 and N15-labeled recombinant protein (NP_006388)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of ribonuclease H2, subunit A (RNASEH2A)
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Rabbit Polyclonal RNAse H2A Antibody
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Specifications

Product Data
Description RNASEH2A MS Standard C13 and N15-labeled recombinant protein (NP_006388)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204032
Predicted MW 33.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_006388
RefSeq Size 1148
RefSeq ORF 897
Synonyms AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8
Locus ID 10535
Cytogenetics 19p13.13
Summary The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
Protein Pathways DNA replication
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