Endothelin 1 (EDN1) (NM_001955) Human Mass Spec Standard

CAT#: PH302217

EDN1 MS Standard C13 and N15-labeled recombinant protein (NP_001946)



  View other "Endothelin 1" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description EDN1 MS Standard C13 and N15-labeled recombinant protein (NP_001946)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202217
Predicted MW 24.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001946
RefSeq Size 2112
RefSeq ORF 636
Synonyms ARCND3; ET1; HDLCQ7; PPET1; QME
Locus ID 1906
Cytogenetics 6p24.1
Summary This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Melanogenesis
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