HMBS (NM_000190) Human Mass Spec Standard

CAT#: PH301362

HMBS MS Standard C13 and N15-labeled recombinant protein (NP_000181)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description HMBS MS Standard C13 and N15-labeled recombinant protein (NP_000181)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201362
Predicted MW 39.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000181
RefSeq Size 1526
RefSeq ORF 1083
Synonyms PBG-D; PBGD; PORC; UPS
Locus ID 3145
Cytogenetics 11q23.3
Summary This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Porphyrin and chlorophyll metabolism
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