CD42d (GP5) (NM_004488) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218870L4V

  • LentiORF®

Lenti ORF particles, GP5 (mGFP-tagged) - Human glycoprotein V (platelet) (GP5), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 11,305.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name CD42d (GP5) (NM_004488) Human Tagged ORF Clone Lentiviral Particle
Synonyms CD42d; GPV
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_004488
ORF Size 1680 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC218870).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_004488.1, NP_004479.1
RefSeq Size 5207 bp
RefSeq ORF 1683 bp
Locus ID 2814
Protein Families Druggable Genome, Transmembrane
Protein Pathways ECM-receptor interaction, Hematopoietic cell lineage
MW 60.8 kDa
Gene Summary Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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