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Dystrophin (DMD) (NM_004019) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC215403L4V
- LentiORF®
-
Lenti ORF particles, DMD (mGFP-tagged) - Human dystrophin (DMD), transcript variant Dp40, 200ul, >10^7 TU/mL
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CNY 8,645.00
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规格
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Specifications
| Product Data | |
| Product Name | Dystrophin (DMD) (NM_004019) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_004019 |
| ORF Size | 1020 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC215403).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_004019.1 |
| RefSeq Size | 1634 bp |
| RefSeq ORF | 1023 bp |
| Locus ID | 1756 |
| Domains | ZnF_ZZ |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis |
| MW | 39.1 kDa |
| Gene Summary | This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016] |
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