United States
Germany
Japan
United Kingdom
China
KCNA1 (NM_000217) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC211000L4V
- LentiORF®
-
Lenti ORF particles, KCNA1 (mGFP-tagged) - Human potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 9,975.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | KCNA1 (NM_000217) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_000217 |
| ORF Size | 1485 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC211000).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000217.2 |
| RefSeq Size | 7983 bp |
| RefSeq ORF | 1488 bp |
| Locus ID | 3736 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| MW | 56.5 kDa |
| Gene Summary | This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
