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HB EGF (HBEGF) (NM_001945) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC207688L1V
- LentiORF®
-
Lenti ORF particles, HBEGF (Myc-DDK tagged) - Human heparin-binding EGF-like growth factor (HBEGF), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | HB EGF (HBEGF) (NM_001945) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | DTR; DTS; DTSF; HEGFL |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_001945 |
| ORF Size | 624 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC207688).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001945.1 |
| RefSeq Size | 2381 bp |
| RefSeq ORF | 627 bp |
| Locus ID | 1839 |
| Domains | EGF |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway |
| MW | 23.1 kDa |
| Gene Summary | Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function] |
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