COX2 (PTGS2) (NM_000963) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC202245L2V
- LentiORF®
Lenti ORF particles, PTGS2 (mGFP-tagged) - Human prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), 200ul, >10^7 TU/mL
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CNY 9,975.00
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CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Product Name | COX2 (PTGS2) (NM_000963) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | COX-2; COX2; GRIPGHS; hCox-2; PGG/HS; PGHS-2; PHS-2 |
Vector | pLenti-C-mGFP |
ACCN | NM_000963 |
ORF Size | 1812 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202245).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000963.1 |
RefSeq Size | 4465 bp |
RefSeq ORF | 1815 bp |
Locus ID | 5743 |
Domains | An_peroxidase, EGF |
Protein Families | Druggable Genome |
Protein Pathways | Arachidonic acid metabolism, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway |
MW | 69 kDa |
Gene Summary | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009] |
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