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Beta Arrestin 2 (ARRB2) (NM_004313) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC201168L4V
- LentiORF®
-
Lenti ORF particles, ARRB2 (mGFP-tagged) - Human arrestin, beta 2 (ARRB2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
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| Product Data | |
| Product Name | Beta Arrestin 2 (ARRB2) (NM_004313) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ARB2; ARR2; BARR2 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_004313 |
| ORF Size | 1227 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC201168).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_004313.3 |
| RefSeq Size | 1936 bp |
| RefSeq ORF | 1230 bp |
| Locus ID | 409 |
| Domains | arrestin |
| Protein Families | Druggable Genome |
| Protein Pathways | Chemokine signaling pathway, Endocytosis, MAPK signaling pathway, Olfactory transduction |
| MW | 46.1 kDa |
| Gene Summary | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] |
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