Mbnl1 (NM_020007) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR225085L3V

  • LentiORF®

Lenti ORF particles, Mbnl1 (Myc-DDK-tagged) - Mouse muscleblind-like 1 (Drosophila) (Mbnl1), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 7,410.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Mbnl1 (NM_020007) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms Mbnl; mKIAA0428
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_020007
ORF Size 1143 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR225085).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_020007.3, NP_064391.2
RefSeq Size 5580 bp
RefSeq ORF 1146 bp
Locus ID 56758
Gene Summary Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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