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Pde9a (NM_008804) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208559L4V
- LentiORF®
-
Lenti ORF particles, Pde9a (GFP-tagged) - Mouse phosphodiesterase 9A (Pde9a), transcript variant 1, 200ul, >10^7 TU/mL
Mouse Protein / Lysate Request
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CNY 11,020.00
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Specifications
| Product Data | |
| Product Name | Pde9a (NM_008804) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | PDE9A1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_008804 |
| ORF Size | 1602 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208559).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008804.4, NP_032830.3 |
| RefSeq Size | 2064 bp |
| RefSeq ORF | 1605 bp |
| Locus ID | 18585 |
| Gene Summary | Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes (PubMed:9624145). Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (PubMed:22328573, PubMed:24746365).[UniProtKB/Swiss-Prot Function] |
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