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Cav1 (NM_007616) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201562L3V
- LentiORF®
-
Lenti ORF particles, Cav1 (Myc-DDK-tagged) - Mouse caveolin 1, caveolae protein (Cav1), 200ul, >10^7 TU/mL
Mouse Protein / Lysate Request
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Cav1 (NM_007616) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Cav; Cav-1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_007616 |
| ORF Size | 534 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201562).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_007616.3 |
| RefSeq Size | 2487 bp |
| RefSeq ORF | 537 bp |
| Locus ID | 12389 |
| Gene Summary | May act as a scaffolding protein within caveolar membranes (By similarity). Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (PubMed:19546242). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity). Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (PubMed:10816572). Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).[UniProtKB/Swiss-Prot Function] |
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