PAQR6 (NM_001272105) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	PRdelta
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC333214 representing NM_001272105. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGCTCAGTCTCAAGCTGCCCCAACTTCTTCAAGTCCACCAGGTGTTCTGGGAAGATGGCATCATGTCT GGCTACCGCCGCCCCACCAGCTCGGCTTTGGACTGTGTCCTCAGCTCCTTCCAGATGACCAACGAGACG GTCAACATCTGGACTCACTTCCTGCCCACCTGGTACTTCCTGTGGCGGCTCCTGGCGCTGGCGGGCGGC CCCGGCTTCCGTGCGGAGCCGTACCACTGGCCGCTGCTGGTCTTCCTGCTGCCCGCCTGCCTCTACCCC TTCGCGTCGTGCTGCGCGCACACCTTCAGCTCCATGTCGCCCCGCATGCGCCACATCTGCTACTTCCTC GACTACGGCGCGCTCAGCCTCTACAGTCTGGGCTGCGCCTTCCCCTATGCCGCCTACTCCATGCCGGCC TCCTGGCTGCACGGCCACCTGCACCAGTTCTTTGTGCCTGCCGCCGCACTCAACTCCTTCCTGTGCACC GGCCTCTCCTGCTACTCCCGTTTCCTGGAGCTGGAAAGCCCTGGGCTCAGTAAGGTCCTCCGCACAGGA GCCTTCGCCTATCCATTCCTGTTCGACAACCTCCCACTCTTTTATCGGCTCGGGCTGTGCTGGGGCAGG GGCCACGGCTGTGGGCAGGAGGCCCTGAGCACCAGCCATGGCTACCATCTCTTCTGCGCGCTGCTCACT GGCTTCCTCTTCGCCTCCCACCTGCCTGAAAGGCTGGCACCAGGACGCTTTGATTACATCGGCCACAGC CACCAGTTATTCCACATCTGTGCAGTGCTGGGCACCCACTTCCAGCTGGAGGCAGTGCTGGCTGATATG GGATCACGCAGAGCCTGGCTGGCCACACAGGAACCTGCCCTGGGCCTGGCAGGCACAGTGGCCACACTG GTCTTGGCTGCAGCTGGGAACCTACTCATTATTGCTGCTTTCACAGCCACCCTGCTTCGGGCCCCCAGT ACATGCCCTCTGCTGCAGGGTGGCCCACTGGAGGGGGGTACCCAGGCCAAACAACAGTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001272105
Insert Size	1026 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001272105.1
RefSeq Size	2143 bp
RefSeq ORF	1026 bp
Locus ID	79957
UniProt ID	Q6TCH4
Protein Families	Druggable Genome, Transmembrane
MW	37.6 kDa
Gene Summary	Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432, PubMed:23161870). Seems to act through a G(s) mediated pathway (PubMed:23161870). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23763432, PubMed:23161870).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) differs in the 5' UTR, uses alternate splice sites in the coding region and initiates translation at an alternate start codon, compared to variant 1. The resulting isoform (3) has distinct N- and C-termini and is shorter, compared to isoform 1.

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