STXBP2 (NM_001272034) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	FHL5; Hunc18b; MUNC18-2; pp10122; UNC18-2; UNC18B
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC333188 representing NM_001272034. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCGCCCTCGGGGCTGAAGGCGGTGGTGGGGGAAAAAATTCTGAGCGGAGTTATTCGGAGTGTCAAG AAGGATGGGGAGTGGAAGGTGCTTATCATGGATCACCCAAGCATGCGCATCTTGTCTTCCTGCTGCAAA ATGTCAGATATCCTGGCTGAGGGCATCACCATTGTTGAAGACATCAACAAACGGCGGGAACCCATTCCC AGTCTGGAGGCCATTTATTTGCTGAGCCCCACGGAGAAGGCTCAGGCCCAGAGAGTGATCCACCTTCCC CAGTCGGTTCAGGCCCTGATCAAAGACTTCCAGGGGACCCCGACTTTCACCTACAAAGCGGCCCATATC TTCTTCACCGACACCTGCCCCGAGCCCCTGTTCAGTGAGCTAGGCCGCTCTCGTCTGGCAAAGGTGGTG AAGACGTTGAAGGAGATTCACCTTGCCTTCCTCCCCTACGAGGCCCAGGTGTTCTCCCTCGATGCTCCC CACAGCACCTACAACCTCTACTGCCCCTTCCGGGCAGAGGAGCGCACGCGGCAGCTCGAGGTGCTGGCC CAGCAGATTGCCACGCTGTGCGCCACCCTGCAGGAGTACCCGGCCATCCGCTACCGCAAGGGCCCAGAG GACACAGCCCAGTTGGCCCACGCCGTCCTGGCCAAGCTGAACGCCTTCAAGGCAGACACTCCCAGTCTG GGCGAGGGCCCAGAGAAAACCCGCTCCCAGCTGCTGATAATGGACCGGGCAGCTGACCCCGTGTCCCCA CTACTGCATGAGCTCACGTTCCAGGCCATGGCGTATGATCTGCTGGACATAGAGCAGGACACATACAGG TATGAGACCACCGGGCTGAGCGAGGCGCGGGAGAAGGCCGTCTTGCTGGACGAGGACGATGACTTGTGG GTGGAGCTTCGCCACATGCATATCGCAGATGTGTCCAAGAAGGTCACGGAGCTCCTGAGGACCTTCTGT GAGAGCAAGAGGCTGACCACGGACAAGGCGAACATCAAAGACCTATCCCAGATCCTGAAAAAGATGCCG CAGTACCAGAAGGAGCTGAATAAGTATTCTACGCACCTGCATCTAGCAGATGATTGTATGAAGCACTTC AAGGGCTCGGTGGAGAAGCTGTGTAGTGTGGAGCAGGACCTGGCCATGGGCTCCGACGCAGAGGGGGAG AAGATCAAGGACTCCATGAAGCTGATCGTTCCGGTGCTGCTGGACGCGGCGGTGCCCGCCTACGACAAG ATCCGGGTCCTGCTGCTCTACATCCTCCTTCGGAATGGTGTGAGTGAGGAGAACCTGGCCAAGCTGATC CAGCATGCCAATGTACAGGCGCACAGCAGCCTCATCCGTAACCTGGAGCAGCTGGGAGGCACTGTCACC AACCCCGGGGGCTCGGGGACCTCCAGCCGGCTGGAGCCGAGAGAACGCATGGAGCCCACCTATCAGCTG TCCCGCTGGACCCCGGTCATCAAGGATGTAATGGAGGACGCCGTGGAGGACCGGCTGGACAGGAACCTG TGGCCCTTCGTATCCGACCCCGCCCCCACGGCCAGCTCCCAGGCCGCTGTCAGTGCCCGCTTCGGTCAC TGGCACAAGAACAAGGCTGGCATAGAAGCCCGGGCGGGCCCCCGGCTCATCGTGTATGTCATGGGCGGT GTGGCCATGTCAGAGATGAGGGCCGCCTACGAGGTGACCAGGGCCACCGAGGGCAAGTGGGAGGTGCTC ATTGGCTCCTCACACATCCTCACCCCGACCCGCTTCCTGGATGACCTGAAGGCACTGGACAAGAAGCTG GAGGACATTGCCCTGCCCTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001272034
Insert Size	1815 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001272034.1
RefSeq Size	1941 bp
RefSeq ORF	1815 bp
Locus ID	6813
UniProt ID	Q15833
Protein Families	Stem cell - Pluripotency
MW	67.7 kDa
Gene Summary	This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013] Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (c).

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