DNAJC6 (NM_001256865) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	DJC6; PARK19
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC332492 representing NM_001256865. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGAGCCCAGCTATGGGGGAGGTCTCTTTGACATGGTAAAAGGAGGTGCAGGGAGGCTCTTTAGTAAC CTAAAGGACAACTTGAAAGACACCCTCAAAGACACATCTTCTAGAGTGATACAATCTGTGACCAGCTAC ACAAAGGGAGATTTAGACTTCACTTATGTTACCTCCAGAATTATTGTGATGTCCTTTCCTCTGGACAAT GTTGACATAGGATTCAGGAATCAGGTTGATGACATTCGAAGCTTTTTGGATTCCAGACATCTTGACCAC TACACAGTATACAATCTGTCACCTAAGTCTTATCGAACTGCCAAGTTTCACAGCCGGGTCTCAGAATGC AGTTGGCCCATTAGGCAGGCTCCCAGTCTGCACAACCTTTTTGCTGTGTGTCGGAATATGTATAACTGG CTACTGCAGAATCCCAAAAATGTCTGTGTTGTCCACTGCTTGGATGGACGGGCGGCATCATCAATTCTG GTTGGTGCTATGTTCATTTTCTGTAATCTCTACTCTACTCCTGGCCCAGCCATTCGATTGCTATATGCA AAGCGACCAGGAATTGGACTTTCACCATCCCATAGGAGATACCTGGGCTATATGTGTGACCTACTGGCA GACAAGCCCTACCGCCCTCACTTCAAGCCTCTCACAATTAAGTCGATCACTGTCAGTCCAATACCCTTT TTCAACAAACAGAGGAATGGATGTCGCCCTTACTGTGATGTACTCATTGGAGAAACCAAAATATATTCG ACTTGCACAGATTTTGAACGAATGAAAGAATATCGTGTCCAAGATGGAAAAATCTTCATTCCCTTGAAC ATCACTGTGCAAGGAGACGTGGTTGTTTCCATGTATCACTTGAGGTCAACCATTGGGAGCCGGCTACAG GCTAAGGTGACCAACACACAGATATTCCAGCTTCAGTTTCACACTGGATTCATACCACTGGACACAACA GTTTTAAAGTTCACCAAGCCTGAGTTAGATGCATGTGATGTACCAGAAAAATATCCTCAGCTATTTCAG GTGACACTGGATGTAGAACTACAGCCCCATGACAAAGTAATAGACTTAACTCCACCATGGGAACATTAC TGCACAAAAGATGTCAATCCCAGCATCCTCTTCTCTTCTCACCAGGAACATCAAGATACGCTGGCCTTA GGAGGACAGGCTCCAATAGATATCCCTCCAGACAACCCCAGGCATTACGGACAAAGTGGTTTCTTTGCC TCTCTCTGTTGGCAAGATCAGAAATCGGAGAAGTCATTCTGTGAGGAGGACCACGCTGCCCTAGTGAAT CAGGAAAGTGAGCAATCAGATGATGAACTTCTGACACTTTCCAGTCCGCATGGCAATGCCAATGGTGAC AAGCCTCATGGAGTCAAGAAGCCCAGCAAAAAGCAGCAGGAGCCAGCAGCCCCTCCACCCCCTGAGGAT GTGGACCTTTTGGGCCTGGAAGGGTCTGCAATGAGTAACAGCTTCTCTCCGCCAGCGGCTCCTCCCACC AATTCTGAACTACTGAGTGACCTGTTTGGGGGTGGAGGTGCAGCTGGTCCCACCCAGGCTGGACAGTCA GGAGTGGAAGATGTGTTTCATCCTAGTGGACCTGCGTCTACCCAGTCAACACCACGCCGCTCTGCCACC TCCACCTCTGCGTCTCCAACCCTAAGAGTGGGAGAAGGTGCCACCTTTGACCCATTTGGAGCACCTTCT AAACCATCAGGTCAGGATTTGCTGGGTTCTTTTCTGAACACATCCAGTGCTTCCAGTGACCCCTTTCTC CAGCCAACAAGAAGTCCTTCGCCCACAGTACATGCTTCTAGTACGCCTGCTGTGAACATTCAGCCAGAT GTTTCTGGAGGTTGGGACTGGCATGCTAAACCAGGAGGCTTTGGAATGGGAAGCAAGTCAGCTGCCACC AGCCCAACCGGATCCTCGCATGGTACTCCCACCCATCAAAGCAAACCCCAGACTCTGGATCCTTTTGCC GACCTTGGGACACTAGGTAGTTCTTCCTTTGCCAGCAAACCCACCACACCAACTGGATTGGGTGGAGGA TTCCCGCCTCTCAGCTCGCCACAGAAGGCGTCTCCCCAGCCTATGGGTGGCGGGTGGCAGCAGGGAGGT GCCTACAACTGGCAGCAGCCACAGCCTAAGCCTCAGCCCAGCATGCCCCACTCCTCTCCCCAGAACCGA CCCAACTACAACGTGAGCTTCTCAGCCATGCCTGGGGGCCAGAACGAACGTGGGAAAGGATCAAGTAAT TTGGAAGGGAAACAAAAAGCAGCTGATTTTGAAGACCTACTCTCTGGTCAAGGTTTCAATGCTCACAAA GACAAAAAGGGGCCTCGGACAATAGCTGAGATGAGAAAGGAGGAAATGGCCAAGGAAATGGATCCTGAG AAATTAAAGATTCTGGAATGGATTGAAGGCAAAGAAAGAAATATCAGAGCCCTTCTTTCCACGATGCAT ACCGTACTATGGGCTGGGGAGACCAAGTGGAAACCAGTTGGCATGGCAGACCTGGTAACACCAGAGCAG GTGAAGAAGGTGTACAGGAAGGCTGTCCTGGTGGTGCACCCAGATAAAGCTACTGGGCAACCCTATGAA CAATACGCAAAGATGATTTTCATGGAGCTCAATGATGCCTGGTCTGAATTTGAAAACCAAGGCCAAAAG CCCTTATATTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001256865
Insert Size	2703 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001256865.1
RefSeq Size	5916 bp
RefSeq ORF	2703 bp
Locus ID	9829
UniProt ID	O75061
Protein Families	Druggable Genome
Protein Pathways	Endocytosis
MW	98.6 kDa
Gene Summary	DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008] Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (3) with a shorter N-terminus, compared to isoform 1.

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