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GCS1 (MOGS) (NM_001146158) Human Untagged Clone
CAT＃: SC327642
MOGS (untagged)-Human mannosyl-oligosaccharide glucosidase (MOGS) transcript variant 2
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDG2B; CWH41; DER7; GCS1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001146158, the custom clone sequence may differ by one or more nucleotides
ATGAAGACCCGCAGCCCGAAGCCCCTCCTCACCGGACTGATGTGGGCGCAGCAGGGCACC ACCCCGGGGACTCCTAAGCTCAGGCACACGTGTGAGCAGGGGGACGGTGTGGGTCCCTAT GGCTGGGAGTTCCACGACGGCCTCTCCTTCGGGCGCCAACACATCCAGGATGGGGCCTTA AGGCTCACCACTGAGTTCGTCAAGAGGCCTGGGGGTCAGCACGGAGGGGACTGGAGCTGG AGAGTGACTGTAGAGCCTCAGGACTCAGGTACTTCTGCCCTCCCTTTGGTCTCCCTGTTC TTCTATGTGGTGACAGATGGCAAGGAAGTCCTACTACCAGAGGTTGGGGCCAAGGGGCAG TTGAAGTTTATCAGTGGGCACACCAGTGAACTTGGTGACTTCCGCTTTACACTTTTGCCA CCAACCAGTCCAGGGGATACAGCCCCCAAGTATGGCAGCTACAATGTCTTCTGGACCTCC AACCCAGGACTGCCCCTGCTGACAGAGATGGTAAAGAGTCGCCTAAATAGCTGGTTTCAG CATCGGCCCCCAGGGGCCCCCCCTGAACGCTACCTCGGCTTGCCAGGATCCCTGAAGTGG GAGGACAGAGGTCCAAGTGGGCAAGGGCAGGGGCAGTTCTTGATACAGCAGGTGACCCTG AAAATTCCCATTTCCATAGAGTTTGTGTTTGAATCAGGCAGTGCCCAGGCAGGAGGAAAT CAAGCCCTGCCAAGACTGGCAGGCAGTCTACTGACCCAGGCCCTGGAGAGCCATGCTGAA GGCTTTAGAGAGCGCTTTGAGAAGACCTTCCAGCTGAAGGAGAAGGGCCTGAGCTCTGGC GAGCAGGTTTTGGGTCAGGCTGCCCTCAGCGGCCTCCTTGGTGGAATTGGCTACTTCTAC GGACAAGGGCTGGTATTGCCAGACATCGGGGTGGAAGGGTCTGAGCAGAAGGTGGACCCA GCCCTCTTTCCACCCGTACCTCTTTTTACAGCAGTGCCCTCCCGGTCATTCTTCCCACGA GGCTTCCTTTGGGATGAAGGCTTTCACCAGCTGGTGGTTCAGCGGTGGGATCCCTCCCTC ACCCGGGAAGCCCTTGGCCACTGGCTGGGGCTGCTAAATGCTGATGGCTGGATTGGGAGG GAGCAGATACTGGGGGATGAGGCCCGAGCCCGGGTGCCTCCAGAATTCCTAGTACAACGA GCAGTCCACGCCAACCCCCCAACCCTACTTTTGCCTGTAGCCCATATGCTAGAGGTTGGT GACCCTGACGACTTGGCTTTCCTCCGAAAGGCCTTGCCCCGCCTGCATGCCTGGTTTTCC TGGCTCCATCAGAGCCAGGCAGGCCCACTGCCACTATCTTACCGCTGGCGGGGACGGGAC CCTGCCTTACCAACCTTACTGAACCCCAAGACCCTACCCTCTGGGCTGGATGACTACCCC CGGGCTTCACACCCTTCAGTAACCGAGCGGCACCTGGACCTGCGATGTTGGGTGGCACTG GGTGCCCGTGTGCTGACGCGGCTGGCAGAGCATCTGGGTGAGGCTGAGGTAGCTGCTGAG CTGGGCCCACTGGCTGCCTCACTGGAGGCAGCAGAGAGCCTGGATGAGCTGCACTGGGCC CCAGAGCTAGGAGTCTTTGCAGACTTTGGGAACCACACAAAAGCAGTACAGCTGAAGCCC AGGCCCCCTCAGGGGCTCGTTCGGGTGGTGGGTCGGCCCCAACCTCAACTGCAGTATGTA GATGCTCTTGGCTATGTCAGTCTTTTTCCCTTGCTGCTGCGACTGCTGGACCCCACCTCA TCCCGCCTTGGGCCCCTGCTGGACATTCTAGCCGACAGCCGCCATCTCTGGAGCCCCTTT GGTTTACGCTCCCTTGCAGCCTCCAGCTCCTTTTATGGCCAGCGCAATTCAGAGCATGAT CCCCCCTACTGGCGGGGTGCTGTGTGGCTCAATGTCAACTACCTGGCTTTGGGAGCACTC CACCACTATGGGCATCTGGAGGGTCCTCACCAGGCTCGGGCTGCCAAACTCCACGGTGAG CTCCGTGCCAACGTGGTAGGCAATGTATGGCGCCAGTACCAGGCTACAGGCTTTCTTTGG GAGCAGTACAGTGACCGCGATGGGCGAGGCATGGGCTGCCGCCCTTTCCACGGCTGGACC AGCCTTGTCTTACTGGCCATGGCTGAAGACTAC |
| Restriction Sites | Please inquire |
| ACCN | NM_001146158 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001146158.1, NP_001139630.1 |
| RefSeq Size | 2584 bp |
| RefSeq ORF | 2196 bp |
| Locus ID | 7841 |
| UniProt ID | Q13724 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Metabolic pathways, N-Glycan biosynthesis |
| Gene Summary | This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] Transcript Variant: This variant (2) lacks a segment that includes the translation start site compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to variant 1. |
Documents
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| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC229007 | MOGS (Myc-DDK-tagged)-Human mannosyl-oligosaccharide glucosidase (MOGS), transcript variant 2 |
CNY 8,360.00 |
|
| RC229007L3 | Lenti-ORF clone of MOGS (Myc-DDK-tagged)-Human mannosyl-oligosaccharide glucosidase (MOGS), transcript variant 2 |
CNY 10,260.00 |
|
| RC229007L4 | Lenti-ORF clone of MOGS (mGFP-tagged)-Human mannosyl-oligosaccharide glucosidase (MOGS), transcript variant 2 |
CNY 10,260.00 |
|
| RG229007 | MOGS (tGFP-tagged) - Human mannosyl-oligosaccharide glucosidase (MOGS), transcript variant 2 |
CNY 9,220.00 |
