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PRKAG2 (NM_024429) Human Untagged Clone
CAT＃: SC322089
PRKAG2 (untagged)-Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant b
CNY 2,400.00
CNY 6,270.00
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AAKG; AAKG2; CMH6; H91620p; WPWS |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322089
GGGAATGACAGTTTGCTGCAGTCCCGTCAATGGGGGAATCTGCCCGAGCTCTGCCTGCAT
TTTGAGCAGCAAAGCAGCTCCAGCCACCAAGACCGTTGCCTGCGCTGTCTTAGGCCAGCC CATGCTGTCTGCCAGCCGCTTGTTGCGCTGCCTTGGGGACTGGGGACACACCCAGCCCCG GTCCCCATCTGTTGCAGACATGCAGTGGCAGCAGCTCGGAGCACAGCCGAACCCTAGAAA TTGCCTGTGCTGAAGGGGCTGGGAAACCCCTTCTCTGATGGACCTTTCGAGTGAGGCAGC AGGATTTGTCAGAGCTGGGAGTGCCGCCCGTCCCCGTCACTCGCATCCTGCCATCCAGCA GCTTACAAGCCTGCACTGCTTATTAGCATCTGGAAGAGAAGACCTCCAGGACCCCTTGGG GCTGAGACCTGAGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAA AGCATTCCTCTCGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCT TCTCCAGAGGCCCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGA CCAGCCCCGGCTCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCT CCCCTCGACGCATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAAGAGTCTTCCCCCA ACTCCAACCCTGCTACCTCGCCCGGGGGCATCAGGTTTTTCTCCCGCTCCAGAAAAACCT CCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCC TGGAATCCTATAAGCACGAGCCTGAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCC CCCCAGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGGCCTCCAC TGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGAC CCGCGGAAGCCGGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGCAGTAGAAGACTCAG AAAGTGGTGTTTACATGCGATTCATGAGGTCACACAAGTGTTATGACATCGTTCCAACCA GTTCAAAGCTTGTTGTCTTTGATACTACATTACAAGTTAAAAAGGCCTTCTTTGCTTTGG TAGCCAACGGTGTCAGAGCAGCGCCACTGTGGGAGAGTAAAAAACAAAGTTTTGTAGGAA TGCTAACAATTACAGATTTCATAAATATACTACATAGATACTATAAATCACCTATGGTAC AGATTTATGAATTAGAGGAACATAAAATTGAAACATGGAGGGAGCTTTATTTACAAGAAA CATTTAAGCCTTTAGTGAATATATCTCCAGATGCAAGCCTCTTCGATGCTGTATACTCCT TGATCAAAAATAAAATCCACAGATTGCCCGTTATTGACCCTATCAGTGGGAATGCACTTT ATATACTTACCCACAAAAGAATCCTCAAGTTCCTCCAGCTTTTTATGTCTGATATGCCAA AGCCTGCCTTCATGAAGCAGAACCTGGATGAGCTTGGAATAGGAACGTACCACAACATTG CCTTCATACATCCAGACACTCCCATCATCAAAGCCTTGAACATATTTGTGGAAAGACGAA TATCAGCTCTGCCTGTTGTGGATGAGTCAGGAAAAGTTGTAGATATTTATTCCAAATTTG ATGTAATTAATCTTGCTGCTGAGAAAACATACAATAACCTAGATATCACGGTGACCCAGG CCCTTCAGCACCGTTCACAGTATTTTGAAGGTGTTGTGAAGTGCAATAAGCTGGAAATAC TGGAGACCATCGTGGACAGAATAGTAAGAGCTGAGGTCCATCGGCTGGTGGTGGTAAATG AAGCAGATAGTATTGTGGGTATTATTTCCCTGTCGGACATTCTGCAAGCCCTGATCCTCA CACCAGCAGGTGCCAAACAAAAGGAGACAGAAACGGAGTGACCGCCGTGAATGTAGACGC CCTAGGAGGAGAACTTGAACAAAGTCTCTGGGTCACGTTTTGCCTCATGAACACTGGCTG CAAGTGGTTAAGAATGTATATCAGGGTTTAACGATAGGTATTTCTTCCAGTGATGTTGAA ATTAAGCTTAAAAAAGAAAGATTTTATGTGCTTGAAGATTCAGGCTTGCATTAAAAGACT GTTTTCAGACCTTTGTCTGAAGGATTTTAAATGCTGTATGTCATTAAAGTGCACTGTGTC CTGAAGTTTTCATTATTTTTCATTTCAAAGAATTCACTGGTATGGAACAGGTGATGTGGC ATAAGGTGAGTGCACGGTATGTTCAGATCACAGTGCCTTATGTCCGAATACAGCAATATG TCACCGCCGCAGCCGGGGCGCACGCGTGTGAAACAACACCGAGCTTGAATGTGGAAGTCT TTGAACCTTTTACCAAATCAGTTTGTTTTCTTTAGATTTGTCAAAAAGTTGTAATTTGAA TATAAATAATTACTTTAAAATTTTAATGACACTTTTACACGTAAGTGTTTTGTTCTGGGC TACCGTGTCAACGAGGCTGCTTTACAACAGCTTTATTTATTTTTACTTTCATGCAATTTT TTTACACATCTTTTGGTGGAGTAAACTTCACCACATCCATGAATAAACTCTCAGTTATTT TGAAATGGCAAATTTCTCATTATTTAAGTTTGGATCTGGAAAGGACATGACTTCTGAAAT AGCCGCTGCTGGGTTTTAAAAGCTGAGGTCTCTCAAAGTGTGGAGGAGACGTTGCAGTCA GGCGGGAGCCAAGTGCCGGGAAGATGTCTATTTTTTTTCTTGTGTATTGAAATGTAAAAT CATGATGTTTGTTATGACTGCTGATGCGATTGTTTTTGTAAATTTTATTGTGGCATATAC AGTATTGTCATACAGTTGAAGAGAAACAATGTTTCCTAATGTAAGTGCTCTGAAAATGTT GACACTGTATATATATATATGAGGATAGTTTGTTTTTTTTTGTTTTGGGTTTTTTTTTTT TCAGATTGAAAAATTAAAATAAATCCTACTATCTAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_024429 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_024429.1, NP_077747.1 |
| RefSeq Size | 2248 bp |
| RefSeq ORF | 987 bp |
| Locus ID | 51422 |
| UniProt ID | Q9UGJ0 |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway |
| Gene Summary | AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (b) contains a distinct 5' UTR and lacks a large in-frame portion of the 5' coding region, compared to variant a. The resulting isoform (b, also referred to as PRKAG2-b) has a much shorter N-terminus when compared to isoform a. Variants b and e encode the same isoform (b). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209888 | PRKAG2 (Myc-DDK-tagged)-Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant b |
CNY 3,990.00 |
|
| RC209888L3 | Lenti-ORF clone of PRKAG2 (Myc-DDK-tagged)-Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant b |
CNY 5,890.00 |
|
| RC209888L4 | Lenti-ORF clone of PRKAG2 (mGFP-tagged)-Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant b |
CNY 5,890.00 |
|
| RG209888 | PRKAG2 (tGFP-tagged) - Human protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant b |
CNY 4,370.00 |
