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Fibrinogen beta chain (FGB) (NM_005141) Human Untagged Clone
CAT＃: SC321032
FGB (untagged)-Human fibrinogen beta chain (FGB), transcript variant 1
CNY 3,656.00
CNY 7,890.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HEL-S-78p |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_005141.2
GGGGCTACATGAAAAGGATGGTTTCTTGGAGCTTCCACAAACTTAAAACCATGAAACATC
TATTATTGCTACTATTGTGTGTTTTTTTAGTTAAGTCCCAAGGTGTCAACGACAATGAGG AGGGTTTCTTCAGTGCCCGTGGTCATCGACCCCTTGACAAGAAGAGAGAAGAGGCTCCCA GCCTGAGGCCTGCCCCACCGCCCATCAGTGGAGGTGGCTATCGGGCTCGTCCAGCCAAAG CAGCTGCCACTCAAAAGAAAGTAGAAAGAAAAGCCCCTGATGCTGGAGGCTGTCTTCACG CTGACCCAGACCTGGGGGTGTTGTGTCCTACAGGATGTCAGTTGCAAGAGGCTTTGCTAC AACAGGAAAGGCCAATCAGAAATAGTGTTGATGAGTTAAATAACAATGTGGAAGCTGTTT CCCAGACCTCCTCTTCTTCCTTTCAGTACATGTATTTGCTGAAAGACCTGTGGCAAAAGA GGCAGAAGCAAGTAAAAGATAATGAAAATGTAGTCAATGAGTACTCCTCAGAACTGGAAA AGCACCAATTATATATAGATGAGACTGTGAATAGCAATATCCCAACTAACCTTCGTGTGC TTCGTTCAATCCTGGAAAACCTGAGAAGCAAAATACAAAAGTTAGAATCTGATGTCTCAG CTCAAATGGAATATTGTCGCACCCCATGCACTGTCAGTTGCAATATTCCTGTGGTGTCTG GCAAAGAATGTGAGGAAATTACCAGGAAAGGAGGTGAAACATCTGAAATGTATCTCATTC AACCTGACAGTTCTGTCAAACCGTATAGAGTATACTGTGACATGAATACAGAAAATGGAG GATGGACAGTGATTCAGAACCGTCAAGACGGTAGTGTTGACTTTGGCAGGAAATGGGATC CATATAAACAGGGATTTGGAAATGTTGCAACCAACACAGATGGGAAGAATTACTGTGGCC TACCAGGTGAATATTGGCTTGGAAATGATAAAATTAGCCAGCTTACCAGGATGGGACCCA CAGAACTTTTGATAGAAATGGAGGACTGGAAAGGAGACAAAGTAAAGGCTCACTATGGAG GATTCACTGTACAGAATGAAGCCAACAAATACCAGATCTCAGTGAACAAATACAGAGGAA CAGCCGGTAATGCCCTCATGGATGGAGCATCTCAGCTGATGGGAGAAAACAGGACCATGA CCATTCACAACGGCATGTTCTTCAGCACGTATGACAGAGACAATGACGGCTGGTTAACAT CAGATCCCAGAAAACAGTGTTCTAAAGAAGACGGTGGTGGATGGTGGTATAATAGATGTC ATGCAGCCAATCCAAACGGCAGATACTACTGGGGTGGACAGTACACCTGGGACATGGCAA AGCATGGCACAGATGATGGTGTAGTATGGATGAATTGGAAGGGGTCATGGTACTCAATGA GGAAGATGAGTATGAAGATCAGGCCCTTCTTCCCACAGCAATAGTCCCCAATACGTAGAT TTTTGCTCTTCTGTATGTGACAACATTTTTGTACATTATGTTATTGGAATTTTCTTTCAT ACATTATATTCCTCTAAAACTCTCAAGCAGACGTGAGTGTGACTTTTTGAAAAAAGTATA GGATAAATTACATTAAAATAGCACATGATTTTCTTTTGTTTTCTTCATTTCTCTTGCTCA CCAAGAAGTAACAAAAGTATAGTTTTGACAGAGTTGGTGTTCATAATTTCAGTTCTAGTT GATTGCGAGAATTTTCAAATAAGGAAGAGGGGTCTTTTATCCTTGTCGTAGGAAAACCAT GACGGAAAGGAAAAACTGATGTTTAAAAGTCCACTTTTAAAACTATATTTATTTATGTAG GATCTGTCAAAGAAAACTTCCAAAAAGATTTATTAATTAAACCAGCCTCTGTTGCAATAA AAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_005141 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005141.2, NP_005132.2 |
| RefSeq Size | 1949 bp |
| RefSeq ORF | 1476 bp |
| Locus ID | 2244 |
| UniProt ID | P02675 |
| Domains | FBG |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
| Gene Summary | The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Fibrinogen serves key roles in hemostasis and antimicrobial host defense. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq, Aug 2020] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210471 | FGB (Myc-DDK-tagged)-Human fibrinogen beta chain (FGB), transcript variant 1 |
CNY 3,656.00 |
|
| RC210471L1 | Lenti ORF clone of Human fibrinogen beta chain (FGB), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210471L2 | Lenti ORF clone of Human fibrinogen beta chain (FGB), transcript variant 1, mGFP tagged |
CNY 6,180.00 |
|
| RC210471L3 | Lenti ORF clone of Human fibrinogen beta chain (FGB), transcript variant 1, Myc-DDK-tagged |
CNY 6,180.00 |
|
| RC210471L4 | Lenti ORF clone of Human fibrinogen beta chain (FGB), transcript variant 1, mGFP tagged |
CNY 6,180.00 |
|
| RG210471 | FGB (tGFP-tagged) - Human fibrinogen beta chain (FGB), transcript variant 1 |
CNY 5,256.00 |
|
| SC112673 | FGB (untagged)-Human fibrinogen beta chain (FGB), transcript variant 1 |
CNY 3,656.00 |
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