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PMVK (NM_006556) Human Untagged Clone
CAT＃: SC319138
PMVK (untagged)-Human phosphomevalonate kinase (PMVK)
CNY 2,400.00
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HUMPMKI; PMK; PMKA; PMKASE; POROK1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_006556.3
GAAGGTTCTGGGCGGGGCTGGACTGTTCTAAGTGAGTTCGGGTGGGGGAGCTTCACGAGG
GGAGGCTGCTCTGTGAAGGAACCGCCTTTCTCTCCGCGTGTCTCACCCTTTTCTCCCCAT ATCTGTTTGGACATGAGCTGAGGGCACGGTCGCGGGCGGTCAGCCCTGTTCGCAGCTACG GCGAGGAGGGGCGCGATTGTTCCTTGTTGCCGCTCCGCTTAGTGGCCGCGTCCATTCCGC GCGGTGTCCCGATTTTAGGGGTAGGGAGAAGTGTCAGCTTCAGGCATCGCGAGGCGTGGC GGCCCCATGGCCCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGG AAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAGAGCAGACTTGGAGCTGATGTCTGT GCTGTCCTCCGGCTCTCTGGTCCACTCAAGGAACAGTATGCTCAGGAGCATGGCTTGAAC TTCCAGAGACTCCTGGACACCAGCACCTACAAGGAGGCCTTTCGGAAGGACATGATCCGC TGGGGAGAGGAGAAACGCCAGGCTGACCCAGGCTTCTTTTGCAGGAAGATTGTGGAGGGC ATCTCCCAGCCCATCTGGCTGGTGAGTGACACACGGAGAGTGTCTGACATCCAGTGGTTT CGGGAGGCCTATGGGGCCGTGACGCAGACGGTCCGCGTTGTAGCGTTGGAGCAGAGCCGA CAGCAGCGGGGCTGGGTGTTCACGCCAGGGGTGGACGATGCTGAGTCAGAATGTGGCCTG GACAACTTCGGGGACTTTGACTGGGTCATCGAGAACCATGGAGTTGAACAGCGCCTGGAG GAGCAGTTGGAGAACCTGATAGAATTTATCCGCTCCAGACTTTAGTCACTAGGTTCTAGG AGTGAGCTGGGGCCTGCTGAGGTGGGGGTGGGGCTGACTCTGCAAAATGGGGGTGTCCCC CGATCCTGGCCGAGGTGAGGAACAGACAGGGGGGGTCTAGATTCTGAGGGGGTTGGTGGA TATTGGGCAAGGCAGGAAACCTCTGGAGACCTCATTTTCTCCATGGGGAAGACAGCCATG CTCTTCAGGAGGAGACTCCAAGGGCAAAGGAGGGTGTCTTGGCTGTGCTTGAAGGCGAAA CCCTGCCATATCCCCAGTGCCAGTCCCCTCAGCCTGTGGTGGCCTTGCATCCTGACTGGA TGTTCTCAGCCCCTTGTTCTGGGCAAGAACCCAGAGCTCCCCAGTGTGGATACTAATAAA CCTCTTGGAGCACACTCTCAAAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAACCTCGGG |
| Restriction Sites | Please inquire |
| ACCN | NM_006556 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006556.3, NP_006547.1 |
| RefSeq Size | 1307 bp |
| RefSeq ORF | 579 bp |
| Locus ID | 10654 |
| UniProt ID | Q15126 |
| Domains | P-mevalo_kinase |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Terpenoid backbone biosynthesis |
| Gene Summary | This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202867 | PMVK (Myc-DDK-tagged)-Human phosphomevalonate kinase (PMVK) |
CNY 2,400.00 |
|
| RC202867L3 | Lenti ORF clone of Human phosphomevalonate kinase (PMVK), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202867L4 | Lenti ORF clone of Human phosphomevalonate kinase (PMVK), mGFP tagged |
CNY 5,890.00 |
|
| RG202867 | PMVK (tGFP-tagged) - Human phosphomevalonate kinase (PMVK) |
CNY 4,000.00 |
