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EYA4 (NM_172103) Human Untagged Clone
CAT＃: SC318057
EYA4 (untagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMD1J; DFNA10 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_172103 edited
GGGAAAAGCCGGGGAGTGACGACTGCGGCGGCTGGGCGCGCTCTCTCATTTTCTTTTCTT CTCCTTTCCCCCCTGTCGCAGTCCGGAGTTTTGGCTCCTCTCCTTTCCTCCTCCCCCTCG GAGCCGGCTTCTCCCTCCGCCCCGCTTCTCCCCCGCTTGTGTACGCTATTTGTTGTGGGG TGGCCGAAGGGGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGACAC TGGAAGGAACGAGAATAAATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAGACA CTTCGGGAACCCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGCTGC TTCTACTTGGGAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTTAAA TGAACAATCAGTAAAGAAAACGTGCACAGAATCAGATGTTTCACAATCTCAGAATTCCAG GTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATACTCC AGGTAGCTCCAAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGAC AGGAGTGTCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCAC GACTGGAGATGGAGCGCTTGACACTTTTACTGGGTCAGTAATTACAAGTAGTGGCTACAG CCCCAGATCAGCACATCAGTATTCCCCACAGCTGTATCCTTCCAAGCCCTATCCACACAT TCTTTCTACACCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCAGTATTCGGG GATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACAGGACAGCCCTACAGCTTGCC CACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACTTTCCCAAAC TCAGTCCCCATTACAGAGTGGCTGCCTCAGTTACAGCCCAGGGTTCTCTACCCCACAGCC AGGCCAGACACCTTATTCTTACCAAATGCCAGGTTCTAGTTTTGCACCATCATCTACTAT TTATGCAAATAATTCAGTTTCCAATTCAACAAATTTCAGTGGTTCACAACAGGATTATCC ATCCTATACAGCCTTTGGCCAAAACCAGTATGCACAGTATTATTCAGCATCAACGTATGG AGCGTATATGACATCGAATAACACAGCCGATGGCACACCCTCTTCAACCTCTACTTATCA GTTGCAGGAATCTCTCCCAGGACTGACTAACCAACCAGGAGAGTTCGATACCATGCAGAG TCCCTCCACACCCATCAAAGATCTTGATGAGAGAACCTGTAGGAGTTCTGGGTCAAAGTC CAGAGGAAGAGGCCGGAAAAATAATCCCTCCCCGCCTCCTGATAGTGACCTGGAGCGTGT GTTTGTCTGGGATTTGGATGAAACCATCATTGTTTTTCACTCACTGCTCACCGGGTCTTA TGCACAGAAGTATGGCAAGGATCCCCCCATGGCTGTAACCCTTGGACTCCGCATGGAAGA AATGATTTTTAATCTTGCTGATACTCATTTGTTTTTTAATGATTTAGAGGAGTGTGATCA AGTTCATATAGATGATGTTTCCTCTGATGATAATGGGCAGGACTTAAGTACCTACAGTTT TGCAACTGATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTTTGCCAACAGGTGT AAGAGGAGGGGTTGACTGGATGAGGAAGTTGGCTTTTCGTTACAGAAGAGTAAAAGAATT ATATAACACCTACAAGAACAACGTTGGAGGACTCCTTGGCCCTGCCAAGAGGGATGCCTG GCTACAGTTAAGGGCAGAGATTGAAGGTCTGACAGATTCCTGGCTAACAAATGCACTTAA GTCTTTATCAATTATTAGCACTAGGAGTAACTGCATAAATGTCTTGGTAACGACAACTCA ACTGATCCCAGCACTTGCGAAGGTTCTACTCTATAGTTTAGGAGGTGCTTTCCCCATTGA GAATATTTACAGTGCAACTAAAATAGGAAAAGAAAGTTGCTTTGAACGAATAATGCAAAG GTTTGGCAGAAAAGTAGTGTATGTTGTAATTGGGGATGGTGTAGAAGAAGAACAGGCAGC AAAAAAGCACAACATGCCCTTCTGGAGGATATCCAGTCACTCAGACCTCCTGGCTCTCCA CCAAGCACTGGAATTAGAGTATTTGTAACTGTGTTCTTTAGCCGGAGATCTATTTTTTAT ATTTCAAGTACACTGAATTTTTATGTGTGATTCAATGCCTCTGGCTCTACACATATAAAT TGTCTTAATGGATGAAATCATATTTGGAATAAAAATTCCAGAATGAAGAATTCAGATTGC TGAATGGAGTTAAACTTTAGTGCTACAGAAAAGAAACTCTATGGTCTTATATTTACAACA CTTTAATGGGTTTTTTAAAAATCTGTGGAGGTTGCTGGTACACACCAAATGAGTCCAAAC TGGAATGAGCAGCTTTAGCAAAGAACTCTTACCTGGCAAAGCAGCAACACACATGCTCCG TCTGACAAGGTGGTCAACAACATTCCTCAAAATGGGAGATCTTCTCAGCCCTGAGGTTTG AATCTGACTTTAGCCTACCTAACCCAGAAAATCTGAATTGGAATGCACTCAGACTGTATA AGGACAGTCCTATTTAGACATGTAATTTGTGTAAATTATTGATGAAAATAATTTACTGTG ACTTTATTAGCAGCTGACTTTCAAAGTGGATGCAATTTTTCTTTCTTTTGTTGGGGAGGG GAATGGGAGGGGAAATGGGAATATAATATTGTCTCTTTTTTAAGTTTGGCAAACAGAATG TTCATACTGATGTGTTGTGCCTTAAAGACAAGACAGCATTTGTGTGTTACAATGTAACTT TGGTTAAAATCTCTGTAGATAATGAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_172103 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_172103.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_172103.2, NP_742101.2 |
| RefSeq Size | 5031 bp |
| RefSeq ORF | 1851 bp |
| Locus ID | 2070 |
| UniProt ID | O95677 |
| Protein Families | Druggable Genome, Phosphatase, Transcription Factors |
| Gene Summary | This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (2) lacks an in-frame segment of the 5' coding region, compared to variant 1. The resulting isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208336 | EYA4 (Myc-DDK-tagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2 |
CNY 3,990.00 |
|
| RC208336L1 | Lenti ORF clone of Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208336L2 | Lenti ORF clone of Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC208336L3 | Lenti ORF clone of Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208336L4 | Lenti ORF clone of Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG208336 | EYA4 (tGFP-tagged) - Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2 |
CNY 4,370.00 |
|
| SC109201 | EYA4 (untagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2 |
CNY 12,608.00 |
