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SCN3A (NM_001081676) Human Untagged Clone
CAT＃: SC316037
SCN3A (untagged)-Human sodium channel, voltage-gated, type III, alpha subunit (SCN3A), transcript variant 2
CNY 37,620.00
货期*
2周
规格
| Cited in 1 publication. |
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DEE62; EIEE62; FFEVF4; NAC3; Nav1.3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001081676 edited
AGAGAGAAAAAAAATTGTAACTAATTTGTAAACCTCTGTGGTCAAAAAAAAAAAAAAAAA AAAAAAGCTGAACAGCTGCAGAGGAAGACACGTTATACCCTAACCATCTTGGATGCTGGG CTTTGTTATGCTGTAATTCATAAGGCTCTGTTTTATCAGAGATTATGGAGCAAGAAAACT GAAGCCAAGCCACATCAAGGTTTGACAGGGATGAGATACCTGTCAAGGATTCATAGTAGA GTGGCTTACTGGGAAAGGAGCAAAGAATCTCTTCTAGGGATATTGTAAGAATAAATGAGA TAATTCACAGAAGGGACCTGGAGCTTTTCCGGAAAAAGGTGCTGTGACTATCTAAGGTAA TTCGTATGCAAGAAGCTACACGTAATTAAATGTGCAGGATGAAAAGATGGCACAGGCACT GTTGGTACCCCCAGGACCTGAAAGCTTCCGCCTTTTTACTAGAGAATCTCTTGCTGCTAT CGAAAAACGTGCTGCAGAAGAGAAAGCCAAGAAGCCCAAAAAGGAACAAGATAATGATGA TGAGAACAAACCAAAGCCAAATAGTGACTTGGAAGCTGGAAAGAACCTTCCATTTATTTA TGGAGACATTCCTCCAGAGATGGTGTCAGAGCCCCTGGAGGACCTGGATCCCTACTATAT CAATAAGAAAACTTTTATAGTAATGAATAAAGGAAAGGCAATTTTCCGATTCAGTGCCAC CTCTGCCTTGTATATTTTAACTCCACTAAACCCTGTTAGGAAAATTGCTATCAAGATTTT GGTACATTCTTTATTCAGCATGCTTATCATGTGCACTATTTTGACCAACTGTGTATTTAT GACCTTGAGCAACCCTCCTGACTGGACAAAGAATGTAGAGTACACATTCACTGGAATCTA TACCTTTGAGTCACTTATAAAAATCTTGGCAAGAGGGTTTTGCTTAGAAGATTTTACGTT TCTTCGTGATCCATGGAACTGGCTGGATTTCAGTGTCATTGTGATGGCATATGTGACAGA GTTTGTGGACCTGGGCAATGTCTCAGCGTTGAGAACATTCAGAGTTCTCCGAGCACTGAA AACAATTTCAGTCATTCCAGGTTTAAAGACCATTGTGGGGGCCCTGATCCAGTCGGTAAA GAAGCTTTCTGATGTGATGATCCTGACTGTGTTCTGTCTGAGCGTGTTTGCTCTCATTGG GCTGCAGCTGTTCATGGGCAATCTGAGGAATAAATGTTTGCAGTGGCCCCCAAGCGATTC TGCTTTTGAAACCAACACCACTTCCTACTTTAATGGCACAATGGATTCAAATGGGACATT TGTTAATGTAACAATGAGCACATTTAACTGGAAGGATTACATTGGAGATGACAGTCACTT TTATGTTTTGGATGGGCAAAAAGACCCTTTACTCTGTGGAAATGGCTCAGATGCAGGCCA GTGTCCAGAAGGATACATCTGTGTGAAGGCTGGTCGAAACCCCAACTATGGCTACACAAG CTTTGACACCTTTAGCTGGGCTTTCCTGTCTCTATTTCGACTCATGACTCAAGACTACTG GGAAAATCTTTACCAGTTGACATTACGTGCTGCTGGGAAAACATACATGATATTTTTTGT CCTGGTCATTTTCTTGGGCTCATTTTATTTGGTGAATTTGATCCTGGCTGTGGTGGCCAT GGCCTATGAGGAGCAGAATCAGGCCACCTTGGAAGAAGCAGAACAAAAAGAGGCCGAATT TCAGCAGATGCTCGAACAGCTTAAAAAGCAACAGGAAGAAGCTCAGGCAGTTGCGGCAGC ATCAGCTGCTTCAAGAGATTTCAGTGGAATAGGTGGGTTAGGAGAGCTGTTGGAAAGTTC TTCAGAAGCATCAAAGTTGAGTTCCAAAAGTGCTAAAGAATGGAGGAACCGAAGGAAGAA AAGAAGACAGAGAGAGCACCTTGAAGGAAACAACAAAGGAGAGAGAGACAGCTTTCCCAA ATCCGAATCTGAAGACAGCGTCAAAAGAAGCAGCTTCCTTTTCTCCATGGATGGAAACAG ACTGACCAGTGACAAAAAATTCTGCTCCCCTCATCAGTCTCTCTTGAGTATCCGTGGCTC CCTGTTTTCCCCAAGACGCAATAGCAAAACAAGCATTTTCAGTTTCAGAGGTCGGGCAAA GGATGTTGGATCTGAAAATGACTTTGCTGATGATGAACACAGCACATTTGAAGACAGCGA AAGCAGGAGAGACTCACTGTTTGTGCCGCACAGACATGGAGAGCGACGCAACAGTAACGG CACCACCACAGAAACGGAAGTCAGAAAGAGAAGGTTAAGCTCTTACCAGATTTCAATGGA GATGCTGGAGGATTCCTCTGGAAGGCAAAGAGCCGTGAGCATAGCCAGCATTCTGACCAA CACAATGGAAGAACTTGAAGAATCTAGACAGAAATGTCCGCCATGCTGGTATAGATTTGC CAATGTGTTCTTGATCTGGGACTGCTGTGATGCATGGTTAAAAGTAAAACATCTTGTGAA TTTAATTGTTATGGATCCATTTGTTGATCTTGCCATCACTATTTGCATTGTCTTAAATAC CCTCTTTATGGCCATGGAGCACTACCCCATGACTGAGCAATTCAGTAGTGTGTTGACTGT AGGAAACCTGGTCTTTACTGGGATTTTCACAGCAGAAATGGTTCTCAAGATCATTGCCAT GGATCCTTATTACTATTTCCAAGAAGGCTGGAATATCTTTGATGGAATTATTGTCAGCCT CAGTTTAATGGAGCTTGGTCTGTCAAATGTGGAGGGATTGTCTGTACTGCGATCATTCAG ACTGCTTAGAGTTTTCAAGTTGGCAAAATCCTGGCCCACACTAAATATGCTAATTAAGAT CATTGGCAATTCTGTGGGGGCTCTAGGAAACCTCACCTTGGTGTTGGCCATCATCGTCTT CATTTTTGCTGTGGTCGGCATGCAGCTCTTTGGTAAGAGCTACAAAGAATGTGTCTGCAA GATCAATGATGACTGTACGCTCCCACGGTGGCACATGAACGACTTCTTCCACTCCTTCCT GATTGTGTTCCGCGTGCTGTGTGGAGAGTGGATAGAGACCATGTGGGACTGTATGGAGGT CGCTGGCCAAACCATGTGCCTTATTGTTTTCATGTTGGTCATGGTCATTGGAAACCTTGT GGTTCTGAACCTCTTTCTGGCCTTATTGTTGAGTTCATTTAGCTCAGACAACCTTGCTGC TACTGATGATGACAATGAAATGAATAATCTGCAGATTGCAGTAGGAAGAATGCAAAAGGG AATTGATTATGTGAAAAATAAGATGCGGGAGTGTTTCCAAAAAGCCTTTTTTAGAAAGCC AAAAGTTATAGAAATCCATGAAGGCAATAAGATAGACAGCTGCATGTCCAATAATACTGG AATTGAAATAAGCAAAGAGCTTAATTATCTTAGAGATGGGAATGGAACCACCAGTGGTGT AGGTACTGGAAGCAGTGTTGAAAAATACGTAATCGATGAAAATGATTATATGTCATTCAT AAACAACCCCAGCCTCACCGTCACAGTGCCAATTGCTGTTGGAGAGTCTGACTTTGAAAA CTTAAATACTGAAGAGTTCAGCAGTGAGTCAGAACTAGAAGAAAGCAAAGAGAAATTAAA TGCAACCAGCTCATCTGAAGGAAGCACAGTTGATGTTGTTCTACCCCGAGAAGGTGAACA AGCTGAAACTGAACCCGAAGAAGACCTTAAACCGGAAGCTTGTTTTACTGAAGGATGTAT TAAAAAGTTTCCATTCTGTCAAGTAAGTACAGAAGAAGGCAAAGGGAAGATCTGGTGGAA TCTTCGAAAAACCTGCTACAGTATTGTTGAGCACAACTGGTTTGAGACTTTCATTGTGTT CATGATCCTTCTCAGTAGTGGTGCATTGGCCTTTGAAGATATATACATTGAACAGCGAAA GACTATCAAAACCATGCTAGAATATGCTGACAAAGTCTTTACCTATATATTCATTCTGGA AATGCTTCTCAAATGGGTTGCTTATGGATTTCAAACATATTTCACTAATGCCTGGTGCTG GCTAGATTTCTTGATCGTTGATGTTTCTTTGGTTAGCCTGGTAGCCAATGCTCTTGGCTA CTCAGAACTCGGTGCCATCAAATCATTACGGACATTAAGAGCTTTAAGACCTCTAAGAGC CTTATCCCGGTTTGAAGGCATGAGGGTGGTTGTGAATGCTCTTGTTGGAGCAATTCCCTC TATCATGAATGTGCTGTTGGTCTGTCTCATCTTCTGGTTGATCTTTAGCATCATGGGTGT GAATTTGTTTGCTGGCAAGTTCTACCACTGTGTTAACATGACAACGGGTAACATGTTTGA CATTAGTGATGTTAACAATTTGAGTGACTGTCAGGCTCTTGGCAAGCAAGCTCGGTGGAA AAACGTGAAAGTAAACTTTGATAATGTTGGCGCTGGCTATCTTGCACTGCTTCAAGTGGC CACATTTAAAGGCTGGATGGATATTATGTATGCAGCTGTTGATTCACGAGATGTTAAACT TCAGCCTGTATATGAAGAAAATCTGTACATGTATTTATACTTTGTCATCTTTATCATCTT TGGGTCATTCTTCACTCTGAATCTATTCATTGGTGTCATCATAGATAACTTCAACCAGCA GAAAAAGAAGTTTGGAGGTCAAGACATCTTTATGACAGAGGAACAGAAAAAATATTACAA TGCAATGAAGAAACTTGGATCCAAGAAACCTCAGAAACCCATACCTCGCCCAGCAAACAA ATTCCAAGGAATGGTCTTTGATTTTGTAACCAGACAAGTCTTTGATATCAGCATCATGAT CCTCATCTGCCTCAACATGGTCACCATGATGGTGGAAACGGATGACCAGGGCAAATACAT GACCCTAGTTTTGTCCCGGATCAACCTAGTGTTCATTGTTCTGTTCACTGGAGAATTTGT GCTGAAGCTCGTCTCCCTCAGACACTACTACTTCACTATAGGCTGGAACATCTTTGACTT TGTGGTGGTGATTCTCTCCATTGTAGGTATGTTTCTGGCTGAGATGATAGAAAAGTATTT TGTGTCCCCTACCTTGTTCCGAGTGATCCGTCTTGCCAGGATTGGCCGAATCCTACGTCT GATCAAAGGAGCAAAGGGGATCCGCACGCTGCTCTTTGCTTTGATGATGTCCCTTCCTGC GTTGTTTAACATCGGCCTCCTGCTCTTCCTGGTCATGTTTATCTATGCCATCTTTGGGAT GTCCAACTTTGCCTATGTTAAAAAGGAAGCTGGAATTGATGACATGTTCAACTTTGAGAC CTTTGGCAACAGCATGATCTGCTTGTTCCAAATTACAACCTCTGCTGGCTGGGATGGATT GCTAGCACCTATTCTTAATAGTGCACCACCCGACTGTGACCCTGACACAATTCACCCTGG CAGCTCAGTTAAGGGAGACTGTGGGAACCCATCTGTTGGGATTTTCTTTTTTGTCAGTTA CATCATCATATCCTTCCTGGTTGTGGTGAACATGTACATCGCGGTCATCCTGGAGAACTT CAGTGTTGCTACTGAAGAAAGTGCAGAGCCCCTGAGTGAGGATGACTTTGAGATGTTCTA TGAGGTTTGGGAAAAGTTTGATCCCGATGCGACCCAGTTTATAGAGTTCTCTAAACTCTC TGATTTTGCAGCTGCCCTGGATCCTCCTCTTCTCATAGCAAAACCCAACAAAGTCCAGCT TATTGCCATGGATCTGCCCATGGTCAGTGGTGACCGGATCCACTGTCTTGATATTTTATT TGCCTTTACAAAGCGTGTTTTGGGTGAGAGTGGAGAGATGGATGCCCTTCGAATACAGAT GGAAGACAGGTTTATGGCATCAAACCCCTCCAAAGTCTCTTATGAGCCTATTACAACCAC TTTGAAACGTAAACAAGAGGAGGTGTCTGCCGCTATCATTCAGCGTAATTTCAGATGTTA TCTTTTAAAGCAAAGGTTAAAAAATATATCAAGTAACTATAACAAAGAGGCAATTAAAGG GAGGATTGACTTACCTATAAAACAAGACATGATTATTGACAAACTAAATGGGAACTCCAC TCCAGAAAAAACAGATGGGAGTTCCTCTACCACCTCTCCTCCTTCCTATGATAGTGTAAC AAAACCAGACAAGGAAAAGTTTGAGAAAGACAAACCAGAAAAAGAAAGCAAAGGAAAAGA GGTCAGAGAAAATCAAAAGTAAAAAGAAACAAAGAATTATCTTTGTGATCAATTGTTTAC AGCCTATGAAGGTAAAGTATATGTGTCAACTGGACTTCAAGAGGAGGTCCATGCCAAACT GACTGTTTTAACAAATACTCATAGTCAGTGCCTATACAAGACAGTGAAGTGACCTCTCTG TCACTGCAACTCTGTGAAGCAGGGTATCAACATTGACAAGAGGTTGCTGTTTTTATTACC AGCTGACACTGCTGAGGAGAAACCCAATGGCTACCTAGACTATAGGGATAGTTGTGCAAA GTGAACATTGTAACTACACCAAACACCTTTAGTACAGTCCTTGCATCCATTCTATTTTTA ACTTCCATATCTGCCATATTTTTACAAAATTTGTTCTAGTGCATTTCCATGGTCCCCAAT TCATAGTTTATTCATAATGCTATGTCACTATTTTTGTAAATGAGGTTTACGTTGAAGAAA CAGTATACAAGAACCCTGTCTCTCAAATGATCAGACAAAGGTGTTTTGCCAGAGAGATAA AATTTTTGCTCAAAACCAGAAAAAGAATTGTAATGGCTACAGTTTCAGTTACTTCCATTT TCTAGATGGCTTTAATTTTGAAAGTATTTTAGTCTGTTATGTTTGTTTCTATCTGAACAG TTATGTGCCTGTAAAGTCTCCTCTAATATTTAAAGGATTATTTTTATGCAAAGTATTCTG TTTCAGCAAGTGCAAATTTTATTCTAAGTTTCAGAGCTCTATATTTAATTTAGGTCAAAT GCTTTCCAAAAAGTAATCTAATAAATCCATTCTAGAAAAATATATCTAAAGTATTGCTTT AGAATAGTTGTTCCACTTTCTGCTGCAGTATTGCTTTGCCATCTTCTGCTCTCAGCAAAG CTGATAGTCTATGTCAATTAAATACCCTATGTTATGTAAATAGTTATTTTATCCTGTGGT GCATGTTTGGGCAAATATATATATAGCCTGATAAACAACTTCTATTAAATCAAATATGTA CCACAGTGTATGTGTCTTTTGCAAGCTTCCAACAGGGATGTATCCTGTATCATTCATTAA ACATAGTTTAAAGGCTATCACTAATGCATGTTAATATTGCCTATGCTGCTCTATTTTACT CAATCCATTCTTCACAAGTCTTGGTTAAAGAATGTCACATATTGGTGATAGAATGAATTC AACCTGCTCTGTCCATTATGTCAAGCAGAATAATTTGAAGCTATTTACAAACACCTTTAC TTTTGCACTTTTAATTCAACATGAGTATCATATGGTATCTCTCTAGATTTCAAGGAAACA CACTGGATACTGCCTACTGACAAAACCTATTCTTCATATTTTGCTAAAAATATGTCTAAA ACTTGTTTAAATATAAATAATGTAAAAATATAATCAACTTTATTTGTCAGCATTTTGTAC ATAAGAAAATTATTTTCAGGTTGATGACATCACAATTTATTTTACTTTATGCTTTTGCTT TTGATTTTTAATCACAATTCCAAACTTTTGAATCCATAAGATTTTTCAATGGATAATTTC CTAAAATAAAAGTTAGATAATGGGTTTTATGGATTTCTTTGTTATAATATATTTTCTACC ATTCCAATAGGAGATACATTGGTCAAACACTCAAACCTAGATCATTTTCTACCAACTATG GTTGCCTCAATATAACCTTTTATTCATAGATGTTTTTTTTTATTCAACTTTTGTAGTATT TACGTATGCAGACTAGTCTTATTTTTTTAATTCCTGCTGCACTAAAGCTATTACAAATAT AACATGGACTTTGTTCTTTTTAGCCATGAACAAAGTGGCAAAGTTGTGCAATTACCTAAC ATGATATAAATTTTTGTTTTTTGCACAAACCAAAAGTTTAATGTTAATTCTTTTTACAAA ACTATTTACTGTAGTGTATTGAAGAACTGCATGCAGGGAATTGCTATTGCTAAAAAGAAT GGTGAGCTACGTCATTATTGAGCCAAAAGAATAAATTTCATTTTTTATTGCATTTCACTT ATTGGCCTCTGGGGTTTTTTGTTTTTGTTTTTTGCTGTTGGCAGTTTAAAATATATATAA TTAATAAAACCTGTGCTTGATCTGACATTTGTATACATAAAAGTTTACATGAATTTTACA ACAAACTAGTGCATGATTCACCAAGCAGTACTACAGAACAAAGGCAAATTAAAAGCAGCT TTGTGAACTTTTATGTGTGCAAAGGATCAAGTTCACATGTTCCAACTTTCAGGTTTGATA ATAATAGTAGTAACCACCTACAATAGCTTTCAATTTCAATTAACTCCCTTGGCTATAAGC ATCTAAACTCATCTTCTTTCAATATAATTGATGCTATCTCCTAATTACTTGGTGGCTAAT AAATGTTACATTCTTTGTTACTTAAATGCATTATATAAACTCCTATGTATACATAAGGTA TTAATGATATAGTTATTGAGAATTTATATTAACTTTTTTTTCAAGAACCCTTGGATTTAT GTGAGGTCAAAACCAAACTCTTATTCTCAGTGGAAAACTCCAGTTGTAATGCATATTTTT AAAGACAATTTGGATCTAAATATGTATTTCATAATTCTCCCATAATAAATTATATAAGGT GGCCAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001081676 |
| Insert Size | 8900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. This clone may be unstable or toxic at high copy number in common E. coli strain. We recommend using a lower copy number E. coli strain, such as CopyCutter strain (http://www.epibio.com/item.asp?ID=435) for transformation and plasmid preparation. Please be aware that the DNA yield could be low. Additional aliquots of this clone can be ordered from OriGene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001081676.1, NP_001075145.1 |
| RefSeq Size | 8994 bp |
| RefSeq ORF | 5856 bp |
| Locus ID | 6328 |
| UniProt ID | Q9NY46 |
| Protein Families | Druggable Genome, Ion Channels: Sodium, Transmembrane |
| Gene Summary | Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2), also known as 12v1, SCN3A-s, or the adult form, uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in a shorter protein (isoform 2). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Propranolol Blocks Cardiac and Neuronal Voltage-Gated Sodium Channels
,null,
Frontiers in Pharmacology
,PubMed ID 21833183
[SCN3A]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212211 | SCN3A (Myc-DDK-tagged)-Human sodium channel, voltage-gated, type III, alpha subunit (SCN3A), transcript variant 2 |
CNY 18,990.00 |
|
| RC212211L1 | Lenti ORF clone of Human sodium channel, voltage-gated, type III, alpha subunit (SCN3A), transcript variant 2, Myc-DDK-tagged |
CNY 20,890.00 |
|
| RG212211 | SCN3A (tGFP-tagged) - Human sodium channel, voltage-gated, type III, alpha subunit (SCN3A), transcript variant 2 |
CNY 20,900.00 |
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