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ARHGEF11 (NM_014784) Human Untagged Clone
CAT＃: SC309607
ARHGEF11 (untagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 1
CNY 29,260.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GTRAP48; PDZ-RHOGEF |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_014784, the custom clone sequence may differ by one or more nucleotides
ATGAGTGTAAGGTTACCCCAGAGTATAGACAGGTTAAGTAGCCTGTCTTCTCTGGGAGAT TCTGCACCAGAGCGCAAGTCCCCTTCCCACCATCGCCAGCCTTCGGATGCCTCTGAGACA ACAGGTCTCGTTCAACGCTGTGTCATTATCCAAAAGGACCAGCATGGCTTCGGCTTCACA GTCAGTGGGGATCGCATTGTTCTGGTGCAGTCTGTGCGGCCTGGAGGTGCAGCCATGAAG GCCGGTGTGAAAGAGGGCGACCGGATCATCAAAGTCAACGGCACCATGGTGACCAATAGC TCACACCTGGAAGTGGTAAAGCTGATCAAATCTGGCGCCTATGTCGCACTCACCCTCCTG GGCTCTTCACCTTCATCCATGGGCATCTCTGGGCTCCAGCAGGACCCATCCCCAGCAGGA GCTCCCCGAATCACGTCAGTGATCCCCTCACCACCACCTCCTCCACCTCTACCACCTCCA CAACGCATCACAGGACCCAAACCTCTGCAGGATCCCGAAGTTCAAAAACATGCCACCCAG ATCCTCAGGAATATGCTGAGGCAGGAAGAAAAAGAATTACAGGACATACTTCCACTATAT GGTGACACCAGCCAGAGACCATCAGAAGGCCGGCTCTCTCTGGATTCCCAGGAGGGGGAC AGTGGCTTGGACTCTGGGACAGAACGCTTTCCTTCCCTCAGTGAGTCATTGATGAATCGG AACTCGGTACTGTCAGACCCTGGGCTAGACAGTCCTCGAACCTCCCCTGTGATCATGGCC AGGGTGGCCCAGCACCACAGGCGGCAGGGCTCGGATGCAGCAGTCCCCTCAACCGGTGAC CAGGGTGTAGATCAAAGCCCAAAGCCTTTAATTATTGGCCCAGAGGAAGACTATGACCCG GGTTATTTCAACAACGAGAGCGACATCATATTCCAGGATCTGGAGAAACTGAAGTCTCGG CCAGCTCACCTGGGGGTTTTTCTACGTTACATCTTCTCTCAGGCGGACCCCAGTCCACTG CTTTTTTACCTGTGTGCAGAAGTTTATCAGCAGGCAAGCCCCAAGGATTCCCGAAGCTTG GGGAAAGACATCTGGAATATTTTCCTGGAGAAAAATGCGCCTCTGAGAGTGAAGATCCCT GAGATGCTACAGGCTGAAATTGACTCGCGCCTGCGGAACAGCGAAGATGCCCGTGGTGTT CTCTGTGAAGCTCAAGAGGCAGCCATGCCTGAGATCCAAGAGCAGATCCACGACTACAGA ACGAAGCGCACACTGGGGCTGGGCAGCCTGTATGGTGAAAATGACCTGCTGGACCTGGAT GGGGACCCTCTCCGAGAGCGCCAAGTGGCTGAGAAGCAGCTGGCTGCCCTTGGAGATATT TTGTCCAAGTATGAGGAAGACAGGAGCGCCCCCATGGACTTCGCCCTCAATACCTACATG AGCCATGCTGGGATCCGTCTTCGAGAGGCACGACCTTCCAACACAGCTGAAAAGGCCCAG TCTGCTCCTGACAAGGACAAGTGGCTACCGTTCTTCCCTAAGACCAAGAAGAGCAGCAAT TCCAAGAAAGAAAAGGATGCCTTGGAGGACAAGAAGCGAAACCCTATCCTCAAATACATT GGGAAGCCCAAAAGCTCTTCTCAAAGCACATTTCATATTCCCTTGTCCCCTGTGGAAGTC AAACCAGGCAATGTGAGGAACATCATTCAGCACTTTGAGAACAACCAGCAGTATGATGCC CCAGAACCTGGGACACAACGACTCTCGACCGGAAGCTTTCCTGAGGACCTGCTGGAGAGT GACAGTTCACGCTCAGAGATTCGCCTGGGCCGCTCTGAAAGCCTCAAGGGCCGGGAAGAG ATGAAACGGTCTCGAAAGGCAGAGAACGTGCCCCGCTCTCGCAGTGATGTTGACATGGAT GCTGCTGCGGAGGCTACTCGCCTGCACCAGTCAGCCTCGTCCTCTACCTCCAGCCTCTCC ACCAGGTCTCTTGAGAACCCAACCCCTCCATTCACTCCCAAAATGGGCCGCAGGAGCATT GAGTCCCCCAGTTTGGGGTTCTGCACAGATACCCTCCTTCCCCACCTCCTAGAGGATGAT CTGGGCCAGCTGTCTGACCTGGAGCCAGAGCCAGATGCCCAAAATTGGCAGCATACAGTG GGCAAGGATGTGGTGGCTGGGCTAACCCAGCGGGAGATTGACCGGCAAGAGGTCATCAAT GAGCTGTTTGTGACTGAAGCTTCCCACCTGCGCACACTCCGGGTCCTGGACCTGATCTTC TACCAGCGAATGAAGAAGGAGAACCTGATGCCCCGGGAGGAGCTGGCCCGGCTCTTCCCG AACCTGCCTGAACTCATAGAGATTCACAATTCCTGGTGTGAAGCCATGAAGAAGCTCCGG GAGGAAGGCCCCATCATCAAAGAGATCAGTGACCTCATGCTGGCCCGGTTTGATGGCCCT GCCCGAGAGGAACTCCAGCAAGTGGCTGCACAGTTCTGTTCCTATCAGTCAATAGCCCTA GAGCTAATCAAGACCAAGCAACGCAAGGAGAGTCGATTCCAGCTCTTCATGCAGGAGGCT GAGAGCCACCCTCAGTGTCGGCGGCTGCAGCTGAGAGACCTCATCATCTCTGAGATGCAG CGGCTCACCAAGTACCCGCTGCTGCTGGAGAGCATCATCAAGCACACAGAGGGTGGCACC TCTGAGCATGAGAAGCTGTGCCGGGCCCGGGACCAGTGCCGGGAGATTCTCAAGTATGTG AATGAAGCGGTAAAACAAACAGAGAACCGCCACCGTTTAGAGGGCTACCAGAAACGCCTG GATGCCACCGCCCTGGAGAGGGCCAGCAACCCCCTGGCAGCAGAGTTCAAGAGCCTGGAT CTTACAACCAGAAAAATGATCCATGAGGGACCCCTGACCTGGAGGATCAGCAAGGATAAG ACCTTGGACCTCCACGTGCTGCTGCTGGAGGACCTCCTAGTGCTGCTACAGAAACAGGAT GAGAAGCTATTGCTGAAGTGCCACAGCAAGACTGCTGTGGGCTCCTCAGACAGCAAGCAG ACCTTCAGCCCCGTGCTCAAGCTCAATGCTGTGCTCATCCGCTCTGTGGCCACAGATAAA CGGGCCTTCTTCATCATCTGCACCTCCAAGCTGGGCCCACCCCAGATCTATGAGCTGGTT GCATTGACGTCATCAGACAAGAACACATGGATGGAGCTCTTAGAAGAGGCCGTGCGGAAT GCCACCAGGCACCCCGGAGCTGCCCCAATGCCCGTCCATCCTCCACCCCCAGGTCCCCGG GAGCCAGCCCAGCAGGGCCCCACACCCAGCAGGGTAGAACTGGATGACTCAGACGTGTTC CATGGTGAACCTGAACCTGAGGAGCTGCCTGGAGGCACTGGGTCCCAGCAGAGGGTCCAA GGGAAGCACCAGGTCCTGCTAGAGGACCCTGAGCAGGAGGGCAGTGCAGAGGAAGAGGAA CTGGGTGTCCTGCCTTGCCCTTCCACATCCCTGGATGGAGAGAACAGGGGCATCAGGACA AGGAACCCCATCCACTTGGCCTTCCCAGGCCCTCTGTTCATGGAAGGGCTCGCTGACTCC GCTCTGGAAGATGTGGAGAACCTGCGACATCTGATCCTGTGGAGCCTGCTGCCAGGTCAC ACCATGGAAACTCAGGCTGCCCAGGAGCCCGAGGACGACCTGACACCCACACCTTCTGTC ATCAGCGTCACCTCTCACCCCTGGGACCCAGGCTCCCCAGGGCAAGCACCCCCTGGGGGT GAAGGGGACAACACCCAGCTTGCAGGGCTGGAGGGGGAACGGCCAGAGCAGGAAGACATG GGTCTCTGTTCTCTGGAACACCTACCCCCAAGGACCAGAAATTCTGGGATATGGGAGTCT CCAGAACTGGACAGGAATCTGGCTGAAGATGCTTCAAGCACAGAGGCAGCAGGAGGTTAC AAAGTTGTGAGAAAAGCTGAGGTGGCAGGCAGCAAGGTTGTCCCTGCACTACCAGAGAGT GGCCAGTCAGAGCCTGGGCCACCTGAAGTGGAAGGCGGAACAAAGGCTACGGGGAACTGC TTTTATGTCAGCATGCCATCAGGACCCCCGGACTCAAGCACCGACCACTCAGAGGCACCC ATGAGCCCCCCTCAGCCTGACAGCCTCCCTGCAGGGCAGACAGAGCCTCAGCCTCAGCTG CAGGGAGGCAACGATGATCCAAGACGCCCCAGCCGCTCTCCTCCAAGCCTGGCCCTCAGG GACGTGGGCATGATCTTCCATACCATTGAGCAGCTCACTCTCAAGCTCAACAGGCTCAAG GATATGGAGCTGGCCCACAGAGAGCTGCTCAAGTCCCTTGGGGGAGAGTCATCTGGTGGC ACCACGCCTGTGGGCAGTTTCCACACAGAAGCAGCTAGATGGACAGATGGCTCCCTCTCA CCTCCCGCTAAGGAGCCCCTAGCTTCTGACTCCAGGAACAGCCATGAACTGGGGCCCTGC CCTGAGGATGGCTCTGACGCCCCCCTGGAAGACAGCACAGCAGACGCAGCCGCGTCACCA GGACCATAA |
| Restriction Sites | Please inquire |
| ACCN | NM_014784 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014784.2, NP_055599.1 |
| RefSeq Size | 6784 bp |
| RefSeq ORF | 4569 bp |
| Locus ID | 9826 |
| UniProt ID | O15085 |
| Domains | RhoGEF, RGS, PDZ, PH |
| Protein Families | Druggable Genome |
| Protein Pathways | Vascular smooth muscle contraction |
| Gene Summary | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the predominant isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217976 | ARHGEF11 (Myc-DDK-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 1 |
CNY 15,200.00 |
|
| RC217976L3 | Lenti-ORF clone of ARHGEF11 (Myc-DDK-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 1 |
CNY 17,100.00 |
|
| RC217976L4 | Lenti-ORF clone of ARHGEF11 (mGFP-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 1 |
CNY 17,100.00 |
|
| RG217976 | ARHGEF11 (tGFP-tagged) - Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 1 |
CNY 16,720.00 |
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