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Nicotinic Acetylcholine Receptor beta 2 (CHRNB2) (NM_000748) Human Untagged Clone
CAT＃: SC309051
CHRNB2 (untagged)-Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2)
CNY 3,744.00
CNY 7,220.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EFNL3; nAChRB2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000748 edited
CCCAGGAACCACCGCGGCGGCCGGCACCACCTGGACCCAGCTCCAGGCGGGCGCGGCTTC AGCACCACGGACAGCGCCCCACCCGCGGCCCTCCCCCCGGCGGCGCGCTCCAGCCGGTGT AGGCGAGGCAGCGAGCTATGCCCGCGGCATGGCCCGGCGCTGCGGCCCCGTGGCGCTGCT CCTTGGCTTCGGCCTCCTCCGGCTGTGCTCAGGGGTGTGGGGTACGGATACAGAGGAGCG GCTGGTGGAGCATCTCCTGGATCCTTCCCGCTACAACAAGCTTATCCGCCCAGCCACCAA TGGCTCTGAGCTGGTGACAGTACAGCTTATGGTGTCACTGGCCCAGCTCATCAGTGTGCA TGAGCGGGAGCAGATCATGACCACCAATGTCTGGCTGACCCAGGAGTGGGAAGATTATCG CCTCACCTGGAAGCCTGAAGAGTTTGACAACATGAAGAAAGTTCGGCTCCCTTCCAAACA CATCTGGCTCCCAGATGTGGTCCTGTACAACAATGCTGACGGCATGTACGAGGTGTCCTT CTATTCCAATGCCGTGGTCTCCTATGATGGCAGCATCTTCTGGCTGCCGCCTGCCATCTA CAAGAGCGCATGCAAGATTGAAGTAAAGCACTTCCCATTTGACCAGCAGAACTGCACCAT GAAGTTCCGTTCGTGGACCTACGACCGCACAGAGATCGACTTGGTGCTGAAGAGTGAGGT GGCCAGCCTGGACGACTTCACACCTAGTGGTGAGTGGGACATCGTGGCGCTGCCGGGCCG GCGCAACGAGAACCCCGACGACTCTACGTACGTGGACATCACGTATGACTTCATCATTCG CCGCAAGCCGCTCTTCTACACCATCAACCTCATCATCCCCTGTGTGCTCATCACCTCGCT AGCCATCCTTGTCTTCTACCTGCCATCCGACTGTGGCGAGAAGATGACGTTGTGCATCTC AGTGCTGCTGGCGCTCACGGTCTTCCTGCTGCTCATCTCCAAGATCGTGCCTCCCACCTC CCTCGACGTGCCGCTCGTCGGCAAGTACCTCATGTTCACCATGGTGCTTGTCACCTTCTC CATCGTCACCAGCGTGTGCGTGCTCAACGTGCACCACCGCTCGCCCACCACGCACACCAT GGCGCCCTGGGTGAAGGTCGTCTTCCTGGAGAAGCTGCCCGCGCTGCTCTTCATGCAGCA GCCACGCCATCATTGCGCCCGTCAGCGCCTGCGCCTGCGGCGACGCCAGCGTGAGCGCGA GGGCGCTGGAGCCCTCTTCTTCCGCGAAGCCCCAGGGGCCGACTCCTGCACGTGCTTCGT CAACCGCGCGTCGGTGCAGGGGTTGGCCGGGGCCTTCGGGGCTGAGCCTGCACCAGTGGC GGGCCCCGGGCGCTCAGGGGAGCCGTGTGGCTGTGGCCTCCGGGAGGCGGTGGACGGCGT GCGCTTCATCGCAGACCACATGCGGAGCGAGGACGATGACCAGAGCGTGAGTGAGGACTG GAAGTACGTCGCCATGGTGATCGACCGCCTCTTCCTCTGGATCTTTGTCTTTGTCTGTGT CTTTGGCACCATCGGCATGTTCCTGCAGCCTCTCTTCCAGAACTACACCACCACCACCTT CCTCCACTCAGACCACTCAGCCCCCAGCTCCAAGTGAGGCCCTTCCTCATCTCCATGCTC TTTCTCGAGCGGAAGGGCGAATTCAGATCTGGTACCGATATCAAGCTTGTCGACTCTAGA TTGCGGCCGCGGTCATAGCTGTTTC >OriGene 5' read for NM_000748 unedited
GGGGGTGTTCAGATATTTGTAAACGACTTACTATAGGGNNCGGCCGCGCAATTCCTCATA CCAGGATAGGCAAGAAGCTGGTTTCTCCTCGCAGCCGGCTCCCTGAGGCCCAGGAACCAC CGCGGCGGCCGGCACCACCTGGACCCAGCTCCAGGCGGGCGCGGCTTCAGCACCACGGAC AGCGCCCCACCCGCGGCCCTCCCCCCGGCGGCGCGCTCCAGCCGGTGTAGGCGAGGCAGC GAGCTATGCCCGCGGCATGGCCCGGCGCTGCGGCCCCGTGGCGCTGCTCCTTGGCTTCGG CCTCCTCCGGCTGTGCTCAGGGGTGTGGGGTACGGATACAGAGGAGCGGCTGGTGGAGCA TCTCCTGGATCCTTCCCGCTACAACAAGCTTATCCGCCCAGCCACCAATGGCTCTGAGCT GGTGACAGTACAGCTTATGGTGTCACTGGCCCAGCTCATCAGTGTGCATGAGCGGGAGCA GATCATGACCACCAATGTCTGGCTGACCCAGGAGTGGGAAGATTATCGCCTCACCTGGAA GCCTGAAGAGTTTGACAACATGAAGAAAGTTCGGCTCCCTTCCAAACACATCTGGCTCCC AGATGTGGTCCTGTACAACAATGCTGACGGCATGTACGAGGTGTCCTTCTATTCCAATGC CGTGGTCTCCTATGATGGCAGCATCTTCTGGCTGCCGCCTGCCATCTACAAGAGCGCATG CAAGATTGAAGTAAAGCACTTCCCATTTGACCAGCAGAACTGCACCATGAAGTTCCGTTC GTGGACCTACGACCGCACAGAGATCGACTTGGTGCTGAAGAGTGAGGTGGCCAGCCTGGA CGACTTCACACCTAGTGGTGAGTGGGACATCGTGGCGCTGCCGGGCCGGCGCAACGAGAA CCCCGACGACTCTACG >OriGene 3' read for NM_000748 unedited
CTGGGAGGCACTTCAGGCCAGAGAGATGGGAGGGTCACAGGGTGCCCCCGGGATCGTTCA GAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACAAGCTTGATATCGGTACCAGATC TGAATTCGCCCTTCCGCTCGAGAAAGAGCATGGAGATGAGGAAGGGCCTCACTTGGAGCT GGGGGCTGAGTGGTCTGAGTGGAGGAAGGTGGTGGTGGTGTAGTTCTGGAAGAGAGGCTG CAGGAACATGCCGATGGTGCCAAAGACACAGACAAAGACAAAGATCCAGAGGAAGAGGCG GTCGATCACCATGGCGACGTACTTCCAGTCCTCACTCACGCTCTGGTCATCGTCCTCGCT CCGCATGTGGTCTGCGATGAAGCGCACGCCGTCCACCGCCTCCCGGAGGCCACAGCCACA CGGCTCCCCTGAGCGCCCGGGGCCCGCCACTGGTGCAGGCTCAGCCCCGAAGGCCCCGGC CAACCCCTGCACCGACGCGCGGTTGACGAAGCACGTGCAGGAGTCAGCCCCTGGGGCTTC GCGGAAGAAGAGGGCTCCAGCGCCCTCGCGCTCACGCTGGCGTCGCCGCAGGCGCAAGCG CTGACGGGCGCAATGATGGCGTGGCTGCTGCATGAAGAGCAGCGCGGGCAGCTTCTCCAG GAAGACGACCTTCACCCATGGCGCCATGGTGTGGCTTGGTGGCCGACCGGTGGTGCACGT TTAAGCCGCCCCACGCTGGTGACCAATGGAGAAGGTGACCAAGCCCCATGGTGGACATTG AGGTAACTTGCCGCCCAAGCGGCACGTCCAG |
| Restriction Sites | Please inquire |
| ACCN | NM_000748 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000748.1, NP_000739.1 |
| RefSeq Size | 2448 bp |
| RefSeq ORF | 1509 bp |
| Locus ID | 1141 |
| UniProt ID | P17787 |
| Domains | Neur_chan_memb, Neur_chan_LBD |
| Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
| Gene Summary | Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
α6-Containing Nicotinic Acetylcholine Receptor Reconstitution Involves Mechanistically Distinct Accessory Components
,Gu, S;Matta, JA;Davini, WB;Dawe, GB;Lord, B;Bredt, DS;,
Cell Rep
,PubMed ID 30673609
[CHRNB2]
|
|
Crystal Structures of Human GlyRα3 Bound to Ivermectin
,Huang, X;Chen, H;Shaffer, PL;,
Structure
,PubMed ID 28479061
[CHRNB2]
|
Documents
| Product Manuals |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210408 | CHRNB2 (Myc-DDK-tagged)-Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2) |
CNY 3,736.00 |
|
| RC210408L1 | Lenti ORF clone of Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210408L2 | Lenti ORF clone of Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2), mGFP tagged |
CNY 5,890.00 |
|
| RC210408L3 | Lenti ORF clone of Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210408L4 | Lenti ORF clone of Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2), mGFP tagged |
CNY 5,890.00 |
|
| RG210408 | CHRNB2 (tGFP-tagged) - Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2) |
CNY 4,370.00 |
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