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Tenascin N (TNN) (NM_022093) Human Untagged Clone
CNY 10,450.00
货期*
2周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | TN-W; TNW |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_022093 edited
GCCACCATGAGTCTCCAGGAGATGTTCCGCTTCCCTATGGGGCTCCTGCTTGGCTCTGTG CTCCTGGTGGCTTCGGCCCCAGCCACTCTGGAGCCTCCCGGCTGCAGCAACAAGGAGCAA CAGGTCACTGTCAGCCACACCTACAAGATCGATGTGCCCAAGTCTGCCTTGGTTCAGGTT GACGCTGACCCTCAGCCCCTCAGTGACGATGGGGCTTCGCTCTTGGCCCTGGGGGAGGCC AGGGAGGAACAGAACATCATCTTCAGGCACAACATCCGCCTTCAGACGCCACAGAAGGAC TGCGAGTTGGCAGGCAGTGTCCAGGACCTCCTGGCCCGGGTGAAGAAGCTGGAGGAAGAG ATGGTGGAGATGAAGGAACAGTGTAGTGCCCAGCGCTGCTGCCAGGGAGTCACTGATCTA AGCCGCCACTGCAGCGGCCACGGGACCTTCTCCCTGGAGACCTGCAGCTGCCACTGCGAA GAGGGCAGGGAGGGCCCCGCCTGCGAGCGGCTGGCCTGCCCCGGGGCGTGCAGCGGCCAC GGGCGTTGCGTGGACGGGCGCTGCCTGTGCCATGAGCCCTACGTGGGTGCCGACTGCGGC TACCCGGCCTGCCCTGAGAACTGCAGCGGACACGGCGAGTGCGTGCGCGGCGTGTGCCAG TGCCACGAAGACTTCATGTCGGAGGACTGCAGCGAGAAGCGCTGTCCCGGCGACTGCAGC GGCCACGGCTTCTGTGACACGGGCGAGTGCTACTGCGAGGAGGGCTTCACAGGCCTGGAC TGTGCCCAGGTGGTCACCCCACAGGGCCTGCAGCTGCTCAAGAACACGGAGGATTCTCTG CTGGTGAGCTGGGAGCCCTCCAGCCAGGTGGATCACTACCTCCTCAGCTACTACCCCCTG GGGAAGGAGCTCTCTGGGAAGCAGATCCAAGTGCCCAAGGAGCAGCACAGCTATGAGATT CTTGGTTTGCTGCCTGGAACCAAGTACATAGTCACCCTGCGTAACGTCAAGAATGAAGTT TCTAGCAGCCCACAGCATCTACTTGCCACCACAGACCTTGCTGTGCTTGGCACTGCCTGG GTGACAGATGAGACTGAGAACTCCCTTGACGTGGAGTGGGAAAACCCCTCAACTGAGGTG GACTACTACAAGCTGCGATATGGCCCCATGACAGGACAGGAGGTAGCTGAGGTCACTGTG CCCAAGAGCAGTGACCCCAAGAGCCGATATGACATCACTGGTCTGCACCCGGGGACTGAG TATAAGATCACGGTGGTGCCCATGAGAGGAGAGCTGGAGGGCAAGCCGATCCTCCTGAAT GGCAGGACAGAAATTGACAGTCCAACCAATGTTGTCACTGATCGAGTGACTGAAGACACA GCAACTGTCTCCTGGGACCCAGTGCAGGCTGTCATAGACAAGTATGTAGTGCGCTACACT TCTGCTGATGGGGACACCAAGGAAATGGCAGTGCACAAGGATGAGAGCAGCACTGTCCTG ACGGGCCTGAAGCCAGGAGAGGCATACAAGGTCTACGTGTGGGCTGAAAGGGGCAACCAG GGGAGCAAGAAAGCTGACACCAATGCCCTCACAGAAATTGACAGCCCAGCAAACCTGGTG ACTGACCGGGTGACTGAGAATACCGCCACCATCTCCTGGGACCCGGTACAGGCCACCATT GACAAGTACGTGGTGCGCTACACCTCTGCTGACGACCAAGAGACCAGAGAGGTTCTGGTG GGGAAGGAGCAGAGCAGCACTGTCCTGACAGGCCTGAGGCCAGGTGTGGAGTACACAGTG CATGTCTGGGCCCAGAAGGGGGACCGAGAGAGCAAGAAGGCTGACACCAACGCCCCGACA GATATTGACAGCCCCAAAAACCTGGTGACTGACCGGGTGACAGAGAATATGGCCACGGTC TCCTGGGACCCGGTGCAGGCCGCCATTGACAAGTACGTGGTGCGCTACACCTCTGCTGGT GGAGAGACCAGGGAGGTTCCGGTGGGGAAGGAGCAGAGCAGCACAGTCCTGACAGGCCTG AGACCGGGTATGGAGTACATGGTGCACGTGTGGGCCCAGAAGGGGGACCAGGAGAGCAAG AAGGCCGACACCAAGGCCCAGACAGACATTGACAGCCCCCAAAACCTGGTGACCGACCGG GTGACAGAGAATATGGCCACTGTCTCCTGGGACCCGGTGCGGGCCACCATTGACAGGTAT GTGGTGCGCTACACCTCTGCCAAGGACGGAGAGACCAGGGAGGTTCCGGTGGGGAAGGAG CAGAGTAGCACTGTCCTGACGGGCCTGAGGCCGGGTGTGGAGTACACGGTGCACGTGTGG GCCCAGAAGGGGGCCCAGGAGAGCAAGAAGGCTGACACCAAGGCCCAGACAGACATTGAC AGCCCCCAAAACCTGGTCACTGACTGGGTGACAGAGAATACAGCCACTGTCTCCTGGGAC CCGGTGCAGGCCACCATTGACAGGTATGTGGTGCACTACACGTCTGCCAACGGAGAGACC AGGGAGGTTCCAGTGGGGAAGGAGCAGAGCAGCACTGTCCTGACGGGCCTGAGGCCGGGC ATGGAGTACACGGTGCACGTGTGGGCCCAGAAGGGGAACCAGGAGAGCAAGAAGGCTGAC ACCAAGGCCCAGACAGAAATTGACGGCCCCAAAAACCTAGTGACTGACTGGGTGACGGAG AATATGGCCACTGTCTCCTGGGACCCGGTTCAGGCCACCATTGACAAGTACATGGTGCGC TACACCTCTGCTGACGGAGAGACCAGGGAGGTTCCGGTGGGGAAGGAGCACAGCAGCACT GTCCTGACGGGCCTGAGACCAGGCATGGAGTACATGGTGCACGTGTGGGCCCAGAAGGGG GCCCAGGAGAGCAAGAAGGCTGACACCAAGGCCCAGACAGAACTCGACCCTCCCAGAAAC CTTCGTCCATCTGCTGTAACGCAGTCTGGTGGCATATTGACCTGGACGCCCCCCTCTGCT CAGATCCACGGCTACATTCTGACTTACCAGTTCCCAGATGGCACAGTTAAGGAGATGCAG CTGGGACGGGAAGACCAGAGGTTTGCGTTGCAAGGCCTTGAGCAAGGCGCCACCTACCCT GTCTCCCTTGTTGCCTTTAAGGGTGGTCGCCGGAGCAGAAATGTATCCACCACCCTCTCC ACAGTTGGTGCCCGTTTCCCACACCCTTCGGACTGCAGTCAGGTTCAGCAGAACAGCAAT GCCGCCAGTGGTCTGTACACCATCTACCTGCATGGCGATGCCAGCCGGCCCCTGCAGGTG TACTGTGACATGGAAACGGACGGAGGTGGCTGGATTGTCTTCCAGAGGCGGAACACTGGG CAGCTGGATTTCTTCAAG:CGATGGAGGAGCTATGTGGAAGGCTTTGGGGACCCCATGAA GGAGTTCTGGCTTGGACTTGACAAGCTACACAACCTCACCACCGGCACTCCAGCGCGGTA TGAGGTGAGAGTGGATTTACAGACTGCCAATGAATCTGCCTATGCTATATATGATTTCTT CCAAGTGGCCTCCAGCAAGGAGCGGTATAAGCTGACAGTTGGGAAATACAGAGGCACGGC AGGGGATGCTCTTACTTACCACAATGGATGGAAGTTTACAACTTTTGACAGAGACAATGA TATCGCACTCAGCAACTGTGCCCTGACACATCATGGTGGCTGGTGGTATAAGAACTGCCA CTTGGCCAACCCTAATGGCAGATATGGGGAGACCAAGCACAGTGAGGGGGTGAACTGGGA GCCTTGGAAAGGACATGAATTCTCCATTCCTTACGTGGAGTTGAAAATCCGCCCTCATGG CTACAGCAGGGAGCCTGTCCTGGGCAGAAAGAAGCGGACGCTGAGAGGAAGGCTGCGAAC GTTCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_022093 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022093.1, NP_071376.1 |
| RefSeq Size | 5008 bp |
| RefSeq ORF | 3900 bp |
| Locus ID | 63923 |
| UniProt ID | Q9UQP3 |
| Protein Families | Druggable Genome |
| Protein Pathways | ECM-receptor interaction, Focal adhesion |
| Gene Summary | Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity) (PubMed:17909022). Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity). During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling (By similarity). In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022).[UniProtKB/Swiss-Prot Function] |
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