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SOCS7 (NM_014598) Human Untagged Clone
CAT＃: SC304138
SOCS7 (untagged)-Human suppressor of cytokine signaling 7 (SOCS7)
CNY 9,310.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NAP4; NCKAP4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC304138 representing NM_014598.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCC TCGGAACTGCTGTGTCCCCGGCACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTC GAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTGGCGGCTCTGGGGCTCGGGCAGCCGGCG GGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCCCCTCCG CAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTG GTCCTGGAGGGCTTGGAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGC AGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTTCTGCTGCAGCCCCCAGGCCCTGAATTACCTCCG GTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAGCAGCAGCAGCAG CAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAG GGCTCCTTCAAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGG GATGGGACCGGCAAGAGGCCTTCTGGAGAGCTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGC TCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACTCAAAGTGCCTTTTCTCCG GTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGC CTGACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATC AGTGGGACGCTGCCTACATCTGTCCTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCT CCGCCTCCTCCACCCCATGCCCCAGATGCATTTCCCCGGATTGCTCCCATCCGAGCAGCTGAATCCCTG CACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCCAGC CTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTG AAAGGGAAACCAGATGGTTCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGT TTCCGATCACAGGGTATCACCCACCACACTAGAATGGAGCACTACAGAGGAACCTTCAGCCTGTGGTGT CATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATGCACTCCAAG AATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGGACTGCCACCAACTCCTGTCCAGCTGCTC TATCCAGTGTCCCGATTCAGCAATGTCAAATCCCTCCAGCACCTTTGCAGATTCCGGATACGACAGCTC GTCAGGATAGATCACATCCCAGATCTCCCACTGCCTAAACCTCTGATCTCTTATATCCGAAAGTTCTAC TACTATGATCCTCAGGAAGAGGTATACCTGTCTCTAAAGGAAGCGCAGCTCATTTCCAAACAGAAGCAA GAGGTGGAACCCTCCACGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_014598 |
| Insert Size | 1746 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014598.3 |
| RefSeq Size | 7978 bp |
| RefSeq ORF | 1746 bp |
| Locus ID | 30837 |
| UniProt ID | O14512 |
| Protein Families | Druggable Genome |
| Protein Pathways | Jak-STAT signaling pathway |
| MW | 63 kDa |
| Gene Summary | Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211558 | SOCS7 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 7 (SOCS7) |
CNY 4,328.00 |
|
| RC211558L3 | Lenti ORF clone of Human suppressor of cytokine signaling 7 (SOCS7), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC211558L4 | Lenti ORF clone of Human suppressor of cytokine signaling 7 (SOCS7), mGFP tagged |
CNY 6,460.00 |
|
| RG211558 | SOCS7 (tGFP-tagged) - Human suppressor of cytokine signaling 7 (SOCS7) |
CNY 5,040.00 |
