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PIK3C2B (NM_002646) Human Untagged Clone
CAT＃: SC303232
PIK3C2B (untagged)-Human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B)
CNY 16,776.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C2-PI3K |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002646 edited
CCCTCCAGAACTGACGTTGGCAGGAAGTAGAGACTTTGTTGCCTGTGTCCCCCATCCTCA CCATGTCTTCGACTCAGGGCAATGGGGAACACTGGAAGTCCCTGGAGTCAGTGGGCATCA GCCGCAAAGAGCTAGCGATGGCCGAAGCCCTGCAGATGGAGTATGATGCCCTGTCCCGGC TCCGGCATGACAAGGAGGAGAACAGAGCCAAGCAGAACGCAGACCCCTCTCTCATCAGCT GGGATGAGCCTGGGGTAGACTTTTACAGCAAGCCAGCAGGAAGGCGGACCGACCTCAAGC TGTTACGCGGTCTCTCTGGCTCTGATCCTACCCTTAACTACAACTCACTCTCCCCACAGG AAGGGCCGCCCAACCACTCTACCTCCCAAGGGCCACAGCCTGGCTCAGATCCCTGGCCCA AAGGCTCCCTGTCTGGAGACTATCTCTACATTTTTGATGGTTCAGATGGGGGAGTCTCTT CGTCCCCAGGACCAGGGGACATAGAGGGCTCTTGCAAGAAACTATCCCCACCTCCTCTGC CTCCCCGAGCTTCTATCTGGGATACCCCTCCCCTGCCTCCCAGAAAGGGGTCCCCCTCAT CCTCCAAGATCTCCCAGCCCAGTGACATCAACACTTTCTCTTTGGTCGAACAATTGCCGG GCAAACTGCTAGAGCATCGGATCCTAGAAGAGGAAGAGGTGCTGGGAGGTGGGGGTCAGG GGCGCCTACTGGGGTCTGTGGACTATGATGGTATCAATGATGCAATTACTAGGCTCAACT TGAAATCGACCTATGATGCGGAGATGTTGCGGGATGCCACCAGGGGCTGGAAGGAGGGCC GAGGGCCGCTGGACTTCAGCAAAGACACCTCTGGAAAACCCGTGGCCAGGAGCAAGACTA TGCCCCCTCAGGTGCCCCCCCGCACCTATGCCTCCCGCTATGGCAACCGAAAGAATGCGA CGCCTGACAAGAACCGCCGGATTTCTGCAGCCCCGGTGGGCTCCCGGCCCCACACTGTTG CCAATGGCCATGAGTTGTTTGAGGTCTCAGAAGAGAGAGATGAGGAGGTTGCTGCATTTT GCCACATGCTGGATATCCTTCGATCTGGCTCTGACATCCAAGACTACTTCCTCACTGGCT ATGTCTGGAGTGCTGTCACCCCTAGCCCAGAGCACCTCGGGGATGAGGTCAACCTGAAGG TGACTGTGTTGTGTGACAGGCTTCAAGAGGCACTCACTTTCACCTGCAACTGTTCCTCCA CTGTAGACTTGCTTATCTACCAGACCCTGTGCTACACCCATGATGACCTGAGGAATGTGG ACGTGGGTGACTTTGTGCTAAAGCCCTGCGGGCTGGAGGAGTTCCTGCAGAACAAGCATG CCTTGGGCAGTCATGAGTACATCCAATACTGCCGCAAGTTTGACATTGACATTCGGCTAC AGCTGATGGAGCAGAAGGTTGTGCGCAGTGACCTGGCCCGGACGGTGAATGATGACCAGA GCCCCTCCACCTTGAACTACCTCGTCCATCTCCAAGAGAGGCCTGTCAAGCAGACCATCA GCAGGCAGGCCCTGAGTCTTCTGTTCGACACTTACCACAATGAGGTGGATGCCTTCCTGC TGGCTGATGGAGACTTCCCACTGAAGGCTGACAGGGTGGTCCAGTCCGTCAAGGCCATCT GCAACGCCCTGGCCGCCGTGGAAACCCCTGAGATCACCAGTGCTCTCAACCAGCTGCCCC CCTGCCCCTCCCGCATGCAGCCTAAAATTCAGAAGGATCCCAGTGTCTTGGCTGTGAGGG AAAACCGAGAGAAGGTCGTGGAAGCCCTGACCGCTGCCATCTTGGACCTGGTGGAGCTGT ACTGCAACACATTCAACGCAGACTTCCAGACGGCAGTGCCCGGGAGCCGCAAGCATGACC TGGTCCAGGAGGCCTGCCATTTCGCCAGGTCCCTGGCCTTTACTGTCTATGCCACCCACC GCATCCCCATCATCTGGGCTACCAGCTATGAAGATTTCTACCTCTCCTGCTCCCTCAGCC ATGGCGGCAAGGAGCTGTGCAGCCCCCTGCAGACCCGAAGAGCTCACTTCTCCAAGTACC TCTTCCACCTCATCGTCTGGGACCAGCAGATCTGCTTCCCAGTGCAGGTGAACCGGCTGC CTCGGGAGACACTGCTGTGTGCCACTCTCTATGCTCTGCCCATCCCCCCACCGGGGAGCT CCTCAGAGGCCAATAAGCAGCGGCGGGTGCCTGAAGCCCTGGGCTGGGTCACTACCCCAC TCTTCAACTTCAGGCAGGTCCTGACCTGTGGCCGGAAGCTTCTGGGTTTGTGGCCAGCAA CACAGGAAAATCCCAGCGCCCGTTGGAGTGCACCTAATTTCCACCAGCCAGACAGTGTCA TCCTGCAGATTGACTTCCCCACCTCGGCCTTTGACATCAAGTTCACCAGCCCCCCTGGAG ACAAGTTCAGCCCCCGCTATGAGTTTGGCAGCCTCCGGGAAGAAGACCAGCGCAAGCTTA AAGACATCATGCAGAAAGAGTCCTTGTACTGGCTCACTGATGCTGACAAGAAGCGCCTGT GGGAGAAGCGATATTACTGCCACTCGGAGGTGAGCTCGCTCCCCCTGGTGCTCGCCAGCG CCCCCAGCTGGGAGTGGGCTTGCCTGCCTGACATCTATGTTCTCCTGAAGCAGTGGACCC ACATGAACCACCAGGATGCCCTGGGGCTCCTGCATGCCACCTTCCCGGACCAGGAGGTGC GTCGTATGGCTGTGCAGTGGATTGGCTCACTCTCAGATGCTGAGCTGCTAGACTACCTGC CCCAGCTGGTACAGGCCCTGAAGTATGAATGCTACCTGGACAGCCCGTTGGTGCGCTTCC TCCTGAAACGAGCTGTGTCTGACTTGAGAGTGACTCACTACTTCTTCTGGTTACTGAAGG ACGGCCTCAAGGACTCTCAGTTCAGCATCCGCTACCAGTATCTGCTGGCAGCCTTACTGT GCTGCTGTGGCAAGGGGCTGAGAGAAGAGTTTAACCGCCAGTGCTGGCTTGTCAATGCCC TGGCCAAACTGGCCCAGCAGGTCCGGGAGGCAGCCCCATCTGCAAGGCAGGGAATCCTCC GCACGGGCCTGGAGGAGGTGAAGCAGTTCTTTGCCCTCAATGGCTCGTGCCGCTTGCCAC TCAGCCCCAGTCTGCTGGTTAAGGGAATTGTGCCCAGGGACTGTTCCTACTTCAACTCCA ATGCTGTCCCCCTCAAACTCTCCTTCCAAAATGTGGATCCCCTGGGTGAGAACATCCGTG TCATCTTCAAGTGTGGGGACGACCTTCGCCAGGACATGCTAACGCTGCAGATGATTCGCA TCATGAGCAAGATCTGGGTCCAGGAGGGGCTGGACATGCGCATGGTCATCTTCCGCTGCT TCTCCACCGGCCGGGGCAGAGGGATGGTGGAGATGATCCCTAATGCTGAGACCCTGCGTA AGATCCAGGTGGAGCATGGGGTGACCGGCTCGTTCAAGGACCGGCCCCTGGCAGACTGGC TGCAGAAACACAACCCTGGGGAGGACGAGTATGAGAAGGCTGTGGAGAACTTTATCTACT CCTGCGCTGGCTGCTGCGTGGCCACGTACGTCTTGGGCATCTGTGACCGACATAACGACA ACATCATGCTGAAGACCACTGGTCACATGTTCCACATTGATTTTGGCCGCTTCCTGGGCC ATGCCCAGATGTTTGGCAACATCAAGCGGGACCGTGCCCCCTTTGTCTTCACCTCGGACA TGGCGTATGTCATCAACGGGGGTGACAAGCCTTCCAGCCGCTTCCATGATTTTGTTGACC TTTGCTGCCAAGCCTACAACCTCATTCGCAAGCACACCCACCTCTTCCTCAACCTTCTGG GCCTGATGTTGTCCTGTGGGATCCCTGAACTCTCAGACCTGGAGGACCTCAAGTATGTGT ACGATGCCCTGAGGCCTCAGGATACAGAGGCCAATGCCACTACCTACTTCACTAGGTTGA TTGAGTCCAGCCTGGGCAGTGTAGCCACAAAGCTCAATTTTTTCATCCATAATCTGGCTC AGATGAAGTTCACGGGCTCAGATGACCGGCTGACCCTCTCCTTTGCCTCCCGAACACACA CTCTCAAGAGCTCTGGCCGAATCAGTGATGTTTTCCTCTGCCGCCATGAGAAGATCTTCC ACCCCAACAAAGGCTATATATATGTGGTAAAGGTGATGCGAGAGAACACTCACGAGGCCA CCTACATCCAGCGGACCTTTGAGGAGTTCCAGGAATTACACAATAAGTTGCGGCTGCTCT TCCCTTCTTCCCACTTGCCCAGCTTCCCTAGTCGCTTCGTGATCGGCCGCTCCCGGGGAG AGGCGGTGGCCGAGCGGCGGAGGGAGGAGCTAAACGGTTACATCTGGCACTTGATCCACG CACCCCCTGAGGTGGCCGAGTGTGATTTGGTGTACACCTTCTTCCACCCACTGCCCCGGG ATGAGAAGGCTATGGGCACCAGCCCAGCTCCTAAGTCCTCAGATGGCACATGGGCCCGGC CCGTCGGAAAGGTGGGAGGGGAGGTGAAGCTGTCCATCTCCTACAAAAACAATAAACTCT TCATCATGGTGATGCATATTCGGGGCTTGCAACTGCTCCAGGATGGAAATGACCCTGACC CCTATGTGAAAATTTACCTCCTTCCTGACCCTCAGAAAACCACTAAGAGGAAAACCAAAG TGGCCCGGAAAACCTGCAATCCTACCTACAATGAGATGTTGGTATATGATGGGATCCCCA AGGGTGACCTGCAGCAGCGGGAGCTCCAGCTGAGCGTGCTGAGTGAGCAGGGATTCTGGG AGAACGTCCTCCTCGGTGAGGTGAACATCCGCCTGCGAGAGCTGGACCTGGCTCAGGAGA AGACCGGCTGGTTCGCCCTGGGATCTCGAAGTCATGGCACCTTGTGAG >OriGene 5' read for NM_002646 unedited
NGGGGGTCAAATTTGTATACGACTCATATAGGGCGGCCGCGAATCGCCCTTCCCTCCAAA ACTGACGTTGGCAGGAAGTAGAGACTTTGTTGCCTGTGTCCCCCATCCTCACCATGTCTT CGACTCAGGGCAATGGGGAACACTGGAAGTCCCTGGAGTCAGTGGGCATCAGCCGCAAAG AGCTAGCGATGGCCGAAGCCCTGCAGATGGAGTATGATGCCCTGTCCCGGCTCCGGCATG ACAAGGAGGAGAACAGAGCCAAGCAGAACGCAGACCCCTCTCTCATCAGCTGGGATGAGC CTGGGGTAGACTTTTACAGCAAGCCAGCAGGAAGGCGGACCGACCTCAAGCTGTTACGCG GTCTCTCTGGCTCTGATCCTACCCTTAACTACAACTCACTCTCCCCACAGGAAGGGCCGC CCAACCACTCTACCTCCCAAGGGCCACAGCCTGGCTCAGATCCCTGGCCCAAAGGCTCCC TGTCTGGAGACTATCTCTACATTTTTGATGGTTCAGATGGGGGAGTCTCTTCGTCCCCAG GACCAGGGGACATAGAGGGCTCTTGCAAGAAACTATCCCCACCTCCTCTGCCTCCCCGAG CTTCTATCTGGGATACCCCTCCCCTGCCTCCCAGAAAGGGGTCCCCCTCATCCTCCAAGA TCTCCCAGCCCAGTGACATCAACACTTTCTCTTTGGTCGAACAATTGCCGGGCAAACTGC TAGAGCATCGGATCCTANAAGAGGAAGAGGTGCTGGGAGGTGGGGGTCAGGGGCGCCTAC TGGGGTCTGTGGACTATGATGGTATCAATGATGCAATTACTANGCTCAACTTGAAATCGA CCTATGATGCGGAGATGTTGCGGGATGCCACCAGGGGCTGG >OriGene 3' read for NM_002646 unedited
NCATTGGGATGGCACTTCAGGCCAGGAGAGCACTGGGGAGGGTCACAGGGTGCCACCCGG GATCTGTTCAGAAACAGCTATGACCGCGGCCGCAATCTAGACTCACAAGGTGCCATGACT TCGAGATCCCAGGGCGAACCAGCCGGTCTTCTCCTGAGCCAGGTCCAGCTCTCGCAGGCG GATGTTCACCTCACCGAGGAGGACGTTCTCCCAGAATCCCTGCTCACTCAGCACGCTCAG CTGGAGCTCCCGCTGCTGCAGGTCACCCTTGGGGATCCCATCATATACCAACATCTCATT GTAGGTAGGATTGCAGGTTTTCCGGGCCACTTTGGTTTTCCTCTTAGTGGTTTTCTGAGG GTCAGGAAGGAGGTAAATTTTCACATAGGGGTCAGGGTCATTTCCATCCTGGAGCAGTTG CAAGCCCCGAATATGCATCACCATGATGAAGAGTTTATTGTTTTTGTAGGAGATGGACAG CTTCACCTCCCCTCCCACCTTTCCGACGGGCCGGGCCCATGTGCCATCTGAGGACTTAGG AGCTGGGCTGGTGCCCATAGCCTTCTCATCCCGGGGCAGTGGGTGGAAGAAGGTGTACAC CANATCACACTCGGCCACCTCAGGGGGTGCGTGGATCAAGTGCCAGATGTAACCGTTTAG CTNCTCCCTCCGCCGCTCGGCCACCGCCTCTCCCCGGGGAGCGCCGATCACGAAGCGACT AAGGAAGCTGGGCCAGTGGGAAGAAGGGGAGAGCAGCCGCCACCTTATTGTGTAATCCTG GAACTTCTCAAAGGTCCGCTGGAAGTAAGTGGGCCCTCTGAGTGTTCTCTCCGAAAACCT TACCACATATTTTAGCCTTTGTGGGGGTGGAAGATCTTCTCAGGGGCGCAGAGAAAAACT CG |
| Restriction Sites | Please inquire |
| ACCN | NM_002646 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002646.2, NP_002637.2 |
| RefSeq Size | 7618 bp |
| RefSeq ORF | 4905 bp |
| Locus ID | 5287 |
| UniProt ID | O00750 |
| Protein Families | Druggable Genome |
| Protein Pathways | Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
| Gene Summary | The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218354 | PIK3C2B (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B) |
CNY 16,768.00 |
|
| RC218354L1 | Lenti-ORF clone of PIK3C2B (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B) |
CNY 19,168.00 |
|
| RC218354L2 | Lenti-ORF clone of PIK3C2B (mGFP-tagged)-Human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B) |
CNY 18,240.00 |
|
| RC218354L3 | Lenti-ORF clone of PIK3C2B (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B) |
CNY 18,240.00 |
|
| RC218354L4 | Lenti-ORF clone of PIK3C2B (mGFP-tagged)-Human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B) |
CNY 18,240.00 |
|
| RG218354 | PIK3C2B (tGFP-tagged) - Human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B) |
CNY 18,368.00 |
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