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Factor XIII (F13B) (NM_001994) Human Untagged Clone
CAT＃: SC303105
F13B (untagged)-Human coagulation factor XIII, B polypeptide (F13B)
CNY 10,550.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FXIIIB |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC303105 representing NM_001994.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAGGTTGAAAAACCTGACTTTTATCATCATATTGATAATCTCAGGAGAACTCTATGCAGAAGAGAAA CCCTGTGGTTTTCCTCATGTGGAAAATGGAAGAATTGCCCAATATTACTATACTTTTAAAAGCTTTTAC TTTCCAATGAGCATAGACAAAAAATTGTCATTTTTCTGCTTGGCTGGTTATACCACTGAAAGTGGAAGA CAAGAAGAGCAAACCACGTGTACAACAGAAGGCTGGTCTCCAGAGCCAAGGTGCTTCAAAAAATGCACT AAGCCTGACCTGAGTAATGGTTACATCTCTGATGTAAAGTTATTGTATAAAATTCAAGAGAACATGCGT TATGGTTGCGCTTCAGGGTACAAAACCACTGGAGGGAAGGATGAAGAAGTGGTTCAATGTCTCTCTGAT GGATGGTCTTCTCAACCAACCTGTAGGAAAGAACATGAAACATGTTTGGCTCCTGAATTATATAATGGA AATTATTCCACAACACAGAAAACATTCAAAGTGAAGGACAAAGTACAATACGAATGTGCTACTGGCTAC TACACAGCTGGAGGAAAGAAGACAGAGGAGGTAGAATGTCTCACATACGGATGGTCTCTCACACCAAAA TGTACCAAATTAAAGTGCTCTTCTTTAAGATTAATTGAAAATGGTTATTTTCATCCTGTAAAGCAAACC TATGAAGAAGGAGATGTCGTTCAGTTTTTCTGTCATGAAAATTATTATCTAAGTGGATCTGATTTAATT CAATGCTATAACTTTGGTTGGTACCCAGAATCTCCTGTATGCGAAGGAAGAAGAAACAGATGTCCTCCT CCACCTCTGCCCATAAACTCCAAAATTCAAACACATTCAACAACTTATCGTCATGGAGAAATAGTTCAT ATAGAATGTGAACTTAATTTTGAGATCCATGGGTCAGCAGAAATACGTTGTGAAGATGGAAAATGGACA GAACCTCCAAAATGCATTGAAGGACAGGAGAAGGTAGCCTGTGAGGAACCACCCTTCATTGAAAATGGT GCAGCAAATTTACACTCTAAGATTTATTACAATGGGGATAAAGTGACATATGCATGTAAAAGCGGCTAC CTTCTCCATGGATCGAATGAGATAACTTGTAATCGTGGAAAATGGACACTTCCTCCTGAGTGTGTTGAA AATAATGAGAATTGTAAGCATCCTCCTGTTGTAATGAATGGGGCTGTTGCAGACGGGATATTGGCAAGC TATGCAACAGGATCCTCAGTGGAATATAGATGCAATGAATATTACTTACTGAGGGGATCAAAAATATCT CGTTGCGAACAAGGAAAATGGTCATCCCCACCTGTTTGCTTGGAACCATGTACTGTTAATGTGGATTAC ATGAACAGAAATAACATAGAAATGAAGTGGAAATATGAAGGGAAAGTCTTACATGGAGATTTAATAGAT TTTGTATGTAAACAGGGATATGACTTATCTCCATTAACCCCATTGTCTGAATTATCTGTGCAGTGCAAC AGAGGAGAAGTGAAATATCCTTTATGTACTAGAAAAGAATCTAAAGGAATGTGCACATCTCCTCCTCTT ATTAAACATGGAGTCATTATTAGTTCAACAGTAGACACCTATGAAAATGGCTCTTCAGTAGAATACAGA TGTTTTGATCACCATTTCCTAGAAGGATCTAGGGAGGCCTATTGTTTAGATGGAATGTGGACTACACCA CCATTGTGTTTAGAGCCATGCACATTATCTTTTACTGAAATGGAAAAGAATAATTTACTTCTGAAATGG GATTTTGACAATAGACCACACATTTTGCATGGTGAATATATTGAGTTTATTTGTAGAGGAGATACTTAT CCAGCTGAATTATATATTACTGGATCTATACTTAGAATGCAATGTGACAGAGGGCAGTTAAAATATCCA AGATGTATTCCAAGACAAAGCACTCTGTCTTATCAAGAACCCTTAAGAACATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001994 |
| Insert Size | 1986 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001994.2 |
| RefSeq Size | 2217 bp |
| RefSeq ORF | 1986 bp |
| Locus ID | 2165 |
| UniProt ID | P05160 |
| Protein Families | Druggable Genome |
| Protein Pathways | Complement and coagulation cascades |
| MW | 75.5 kDa |
| Gene Summary | This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219609 | F13B (Myc-DDK-tagged)-Human coagulation factor XIII, B polypeptide (F13B) |
CNY 4,560.00 |
|
| RC219609L3 | Lenti ORF clone of Human coagulation factor XIII, B polypeptide (F13B), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC219609L4 | Lenti ORF clone of Human coagulation factor XIII, B polypeptide (F13B), mGFP tagged |
CNY 6,460.00 |
|
| RG219609 | F13B (tGFP-tagged) - Human coagulation factor XIII, B polypeptide (F13B) |
CNY 5,040.00 |
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