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ATP2B3 (NM_001001344) Human Untagged Clone
CAT＃: SC300169
ATP2B3 (untagged)-Human ATPase, Ca++ transporting, plasma membrane 3 (ATP2B3), transcript variant 2
CNY 23,560.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CFAP39; CLA2; OPCA; PMCA3; PMCA3a; SCAX1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC300169 representing NM_001001344.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGCGACATGGCCAATAGTTCCATCGAGTTCCACCCCAAGCCCCAGCAGCAGCGGGATGTCCCCCAG GCTGGAGGCTTTGGGTGCACGCTGGCGGAGCTGCGCACCCTCATGGAGCTGCGAGGGGCCGAGGCGCTG CAGAAGATCGAGGAGGCCTACGGGGATGTCAGCGGGCTCTGCCGGAGGCTGAAGACCTCACCCACAGAG GGCCTGGCGGACAACACCAATGACCTGGAGAAGCGCAGGCAGATCTACGGGCAGAACTTCATCCCCCCA AAGCAACCCAAGACCTTCCTGCAGCTGGTGTGGGAGGCCCTGCAGGACGTGACCCTCATCATCCTGGAG GTGGCTGCCATCGTCTCTCTGGGCCTCTCGTTCTATGCGCCGCCAGGAGAGGAGAGTGAAGCCTGTGGG AATGTGTCGGGAGGCGCAGAAGATGAGGGCGAGGCCGAAGCTGGCTGGATCGAGGGGGCTGCCATCCTG CTGTCCGTCATCTGTGTGGTGCTGGTCACGGCCTTCAATGACTGGAGCAAGGAGAAGCAGTTCCGAGGC CTGCAGAGCCGAATTGAGCAGGAGCAGAAGTTCACGGTCATCCGGAACGGGCAGCTCCTCCAGGTCCCC GTGGCTGCGCTGGTGGTGGGGGACATTGCCCAGGTCAAGTACGGCGACCTGCTGCCAGCCGACGGCGTG CTCATCCAGGCCAATGACCTCAAGATCGACGAGAGCTCCCTGACGGGCGAGTCTGACCACGTGCGCAAG TCAGCTGACAAAGATCCCATGCTGCTCTCAGGCACTCATGTCATGGAAGGTTCTGGAAGAATGGTGGTG ACCGCCGTTGGCGTGAATTCCCAGACAGGCATCATCTTCACGCTGCTTGGAGCTGGCGGAGAGGAGGAA GAGAAGAAAGATAAGAAAGGCAAGCAGCAGGATGGGGCCATGGAGAGTAGCCAGACCAAAGCTAAGAAG CAGGATGGTGCAGTGGCCATGGAGATGCAGCCCCTGAAGAGCGCGGAGGGTGGGGAGATGGAGGAGCGG GAGAAGAAGAAAGCCAACGCACCCAAAAAGGAGAAGTCTGTCCTTCAGGGGAAGCTCACAAAGCTAGCC GTGCAGATCGGGAAAGCAGGGCTGGTGATGTCTGCCATCACCGTCATCATCCTGGTCCTCTACTTTGTG ATTGAGACGTTTGTCGTGGAAGGCCGGACATGGCTGGCAGAGTGCACGCCGGTCTATGTACAATACTTC GTGAAGTTCTTCATCATTGGTGTCACTGTGCTGGTCGTGGCTGTCCCAGAGGGCCTGCCTCTTGCTGTC ACCATCTCCTTAGCTTACTCTGTCAAGAAAATGATGAAAGACAACAACCTGGTGCGCCACCTGGATGCC TGCGAGACCATGGGCAACGCCACAGCCATCTGCTCCGACAAGACGGGCACGCTCACCACCAACCGTATG ACCGTGGTCCAGTCCTACCTAGGAGACACCCACTACAAAGAGATTCCGGCCCCCAGCGCCCTGACCCCT AAGATCCTCGACCTCCTGGTCCATGCCATCTCCATCAACAGTGCCTATACCACCAAAATACTACCTCCT GAGAAGGAAGGCGCCCTCCCACGCCAGGTGGGCAATAAGACGGAGTGCGCCCTGCTGGGCTTCGTCTTG GACCTGAAGCGGGACTTCCAGCCCGTGCGCGAGCAGATCCCGGAAGACAAGCTTTACAAAGTGTACACC TTCAACTCGGTCCGCAAGTCCATGAGCACAGTCATCCGCATGCCCGACGGTGGCTTCCGCCTCTTCAGC AAGGGGGCCTCAGAGATCCTCTTGAAAAAGTGCACCAACATCTTGAACAGCAATGGCGAACTCCGGGGC TTTCGGCCTCGGGACCGGGACGACATGGTGAGGAAGATCATCGAGCCGATGGCTTGCGATGGCCTCCGC ACCATCTGCATCGCCTACCGGGACTTCTCTGCAGGCCAGGAGCCCGACTGGGACAACGAGAATGAGGTC GTGGGTGACCTCACCTGCATAGCTGTCGTGGGCATTGAGGACCCTGTGCGGCCCGAGGTCCCTGAAGCT ATCCGAAAATGCCAGCGTGCTGGCATCACAGTCCGCATGGTGACTGGGGACAACATCAACACGGCCCGG GCCATCGCAGCCAAATGCGGCATCATCCAGCCCGGGGAGGACTTCCTGTGCCTAGAAGGGAAGGAGTTC AACCGGCGGATCCGCAATGAGAAAGGCGAGATAGAACAGGAGCGGCTGGACAAGGTGTGGCCCAAGCTG AGGGTGCTGGCCCGGTCGTCTCCCACCGACAAGCACACACTGGTCAAAGGGATTATCGACAGCACCACT GGTGAGCAGCGGCAGGTGGTGGCTGTGACAGGGGATGGCACCAACGATGGGCCGGCCCTCAAGAAGGCG GACGTGGGCTTCGCCATGGGCATCGCAGGGACCGACGTGGCCAAGGAGGCCTCCGACATCATCCTGACC GATGACAACTTCACCAGCATCGTCAAGGCAGTCATGTGGGGCCGTAACGTCTATGACAGCATCTCCAAG TTCCTGCAGTTTCAACTGACGGTCAATGTGGTGGCTGTGATCGTGGCCTTCACAGGTGCCTGCATTACT CAGGACTCTCCTCTCAAAGCCGTGCAGATGTTGTGGGTGAACTTGATCATGGACACATTTGCCTCTCTG GCCCTGGCGACGGAGCCACCCACAGAGTCGCTGCTGCTGCGGAAGCCGTACGGCCGCGACAAGCCCCTC ATCTCCCGCACCATGATGAAGAACATTCTGGGCCACGCCGTGTACCAGCTCGCCATCATCTTCACCCTG CTGTTTGTCGGGGAGCTCTTCTTCGACATCGACAGCGGGAGGAATGCGCCCCTGCACTCGCCACCCTCA GAGCACTACACCATCATCTTCAACACGTTCGTCATGATGCAGCTCTTTAACGAGATCAACGCCCGCAAG ATCCACGGCGAGAGGAACGTGTTCGACGGCATCTTCAGCAACCCCATCTTCTGCACCATCGTTTTGGGC ACTTTCGGGATTCAGATTGTCATCGTCCAGTTTGGCGGGAAGCCCTTCAGCTGCTCCCCACTATCCACA GAACAGTGGCTCTGGTGCCTGTTTGTTGGTGTTGGGGAGCTGGTCTGGGGACAGGTCATTGCCACCATC CCCACCAGCCAGCTCAAGTGCCTGAAGGAAGCCGGGCACGGGCCCGGGAAGGACGAGATGACCGACGAG GAGCTGGCCGAAGGCGAGGAAGAGATCGACCATGCCGAGCGGGAGCTCCGCAGGGGCCAGATCCTCTGG TTCCGGGGCCTGAACCGGATTCAGACGCAGATCCGGGTGGTGAAAGCGTTCCGTAGCTCGCTCTATGAA GGCCTGGAGAAACCAGAATCCAAGACCTCCATTCACAACTTCATGGCCACGCCCGAGTTTCTGATCAAT GACTACACCCACAACATCCCGCTCATTGACGACACGGACGTGGACGAGAACGAGGAGCGCCTCCGGGCC CCCCCGCCCCCGTCCCCCAACCAGAACAACAACGCCATAGACAGCGGCATCTACCTGACCACGCATGTC ACCAAGTCAGCTACCTCTTCAGTGTTTTCCTCCAGTCCCGGGAGCCCGCTCCACAGCGTGGAGACGTCC CTCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001001344 |
| Insert Size | 3663 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001001344.2 |
| RefSeq Size | 6420 bp |
| RefSeq ORF | 3663 bp |
| Locus ID | 492 |
| UniProt ID | Q16720 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Calcium signaling pathway |
| MW | 134.2 kDa |
| Gene Summary | The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an exon in the coding region, which leads to a frameshift, compared to variant 1. The resulting isoform (3b) contains a longer and distinct C-terminus compared to isoform 3a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213737 | ATP2B3 (Myc-DDK-tagged)-Human ATPase, Ca++ transporting, plasma membrane 3 (ATP2B3), transcript variant 2 |
CNY 8,496.00 |
|
| RC213737L3 | Lenti ORF clone of Human ATPase, Ca++ transporting, plasma membrane 3 (ATP2B3), transcript variant 2, Myc-DDK-tagged |
CNY 14,060.00 |
|
| RC213737L4 | Lenti ORF clone of Human ATPase, Ca++ transporting, plasma membrane 3 (ATP2B3), transcript variant 2, mGFP tagged |
CNY 14,060.00 |
|
| RG213737 | ATP2B3 (tGFP-tagged) - Human ATPase, Ca++ transporting, plasma membrane 3 (ATP2B3), transcript variant 2 |
CNY 13,400.00 |
