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NMDAR2C (GRIN2C) (NM_000835) Human Untagged Clone
CAT＃: SC300138
GRIN2C (untagged)-Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C)
CNY 12,888.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GluN2C; NMDAR2C; NR2C |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000835 edited
CATGGGTGGGGCCCTGGGGCCGGCCCTGTTGCTCACCTCGCTCTTCGGTGCCTGGGCAGG GCTGGGTCCGGGGCAGGGCGAGCAGGGCATGACGGTGGCCGTGGTGTTTAGCAGCTCAGG GCCGCCCCAGGCCCAGTTCCGTGCCCGCCTCACCCCCCAGAGCTTCCTGGACCTACCCCT GGAGATCCAGCCGCTCACAGTTGGGGTCAACACCACCAACCCCAGCAGCCTCCTCACCCA GATCTGCGGCCTCCTGGGTGCTGCCCACGTCCACGGCATTGTCTTTGAGGACAACGTGGA CACCGAGGCGGTGGCCCAGATCCTTGACTTCATCTCCTCCCAGACCCATGTGCCCATCCT CAGCATCAGCGGAGGCTCTGCTGTGGTCCTCACCCCCAAGGAGCCGGGCTCCGCCTTCCT GCAGCTGGGCGTGTCCCTGGAGCAGCAGCTGCAGGTGCTGTTCAAGGTGCTGGAAGAGTA CGACTGGAGCGCCTTCGCCGTCATCACCAGCCTGCACCCGGGCCACGCGCTCTTCCTGGA GGGCGTGCGCGCCGTCGCCGACGCCAGCCACGTGAGTTGGCGGCTGCTGGACGTGGTCAC GCTGGAGCTGGGCCCGGGAGGGCCGCGCGCGCGCACGCAGCGCCTGCTGCGCCAGCTCGA CGCGCCCGTGTTTGTGGCCTACTGCTCGCGCGAGGAGGCCGAGGTGCTCTTCGCCGAGGC GGCGCAGGCCGGTCTGGTGGGGCCCGGCCACGTGTGGCTGGTGCCCAACCTGGCGCTGGG CAGCACCGATGCGCCCCCCGCCACCTTCCCCGTGGGCCTCATCAGCGTCGTCACCGAGAG CTGGCGCCTCAGCCTGCGCCAGAAGGTGCGCGACGGCGTGGCCATTCTGGCCCTGGGCGC CCACAGCTACTGGCGCCAGCATGGAACCCTGCCAGCCCCGGCCGGGGACTGCCGTGTTCA CCCTGGGCCCGTCAGCCCTGCCCGGGAGGCCTTCTACAGGCACCTACTGAATGTCACCTG GGAGGGCCGAGACTTCTCCTTCAGCCCTGGTGGGTACCTGGTCCAGCCCACCATGGTGGT GATCGCCCTCAACCGGCACCGCCTCTGGGAGATGGTGGGGCGCTGGGAGCATGGCGTCCT ATACATGAAGTACCCCGTGTGGCCTCGCTACAGTGCCTCTCTGCAGCCTGTGGTGGACAG TCGGCACCTGACGGTGGCCACGCTGGAAGAGCGGCCCTTTGTCATCGTGGAGAGCCCTGA CCCTGGCACAGGAGGCTGTGTCCCCAACACCGTGCCCTGCCGCAGGCAGAGCAACCACAC CTTCAGCAGCGGGGACGTGGCCCCCTACACCAAGCTCTGCTGTAAGGGATTCTGCATCGA CATCCTCAAGAAGCTGGCCAGAGTGGTCAAATTCTCCTACGACCTGTACCTGGTGACCAA CGGCAAGCATGGCAAGCGGGTGCGCGGCGTATGGAACGGCATGATTGGGGAGGTGTACTA CAAGCGGGCAGACATGGCCATCGGCTCCCTCACCATCAATGAGGAACGCTCCGAGATCGT AGACTTCTCTGTACCCTTTGTGGAGACGGGCATCAGTGTGATGGTGGCTCGCAGCAATGG CACCGTCTCCCCCTCGGCCTTCTTGGAGCCATATAGCCCTGCAGTGTGGGTGATGATGTT TGTCATGTGCCTCACTGTGGTGGCCATCACCGTCTTCATGTTCGAGTACTTCAGCCCTGT CAGCTACAACCAGAACCTCACCAGAGGCAAGAAGTCCGGGGGCCCAGCTTTCACTATCGG CAAGTCCGTGTGGCTGCTGTGGGCGCTGGTCTTCAACAACTCAGTGCCCATCGAGAACCC GCGGGGCACCACCAGCAAGATCATGGTTCTGGTCTGGGCCTTCTTTGCTGTCATCTTCCT CGCCAGCTACACGGCCAACCTGGCCGCCTTCATGATCCAAGAGCAATACATCGACACTGT GTCGGGCCTCAGTGACAAGAAGTTTCAGCGGCCTCAAGATCAGTACCCACCTTTCCGCTT CGGCACGGTGCCCAACGGCAGCACGGAGCGGAACATCCGCAGTAACTACCGTGACATGCA CACCCACATGGTCAAGTTCAACCAGCGCTCGGTGGAGGACGCGCTCACCAGCCTCAAGAT GGGGAAGCTGGATGCCTTCATCTATGATGCTGCTGTCCTCAACTACATGGCAGGCAAGGA CGAGGGCTGCAAGCTGGTCACCATTGGGTCTGGCAAGGTCTTTGCTACCACTGGCTACGG CATCGCCATGCAGAAGGACTCCCACTGGAAGCGGGCCATAGACCTGGCGCTCTTGCAGTT CCTGGGGGACGGAGAGACACAGAAACTGGAGACAGTGTGGCTCTCAGGGATCTGCCAGAA TGAGAAGAACGAGGTGATGAGCAGCAAGCTGGACATCGACAACATGGCAGGCGTCTTCTA CATGCTGCTGGTGGCCATGGGGCTGGCCCTGCTGGTCTTCGCCTGGGAGCACCTGGTCTA CTGGAAGCTGCGCCACTCGGTGCCCAACTCATCCCAGCTGGACTTCCTGCTGGCTTTCAG CAGGGGCATCTACAGCTGCTTCAGCGGGGTGCAGAGCCTCGCCAGCCCACCGCGGCAGGC CAGCCCGGACCTCACGGCCAGCTCGGCCCAGGCCAGCGTGCTCAAGATGCTGCAGGCAGC CCGCGACATGGTGACCACGGCGGGCGTAAGCAGCTCCCTGGACCGCGCCACTCGCACCAT CGAGAATTGGGGTGGCGGCCGCCGTGCGCCCCCACCGTCCCCCTGCCCGACCCCGCGGTC TGGCCCCAGCCCATGCCTGCCCACCCCCGACCCGCCCCCAGAGCCGAGCCCCACGGGCTG GGGACCGCCAGACGGGGGTCGCGCGGCGCTTGTGCGCAGGGCTCCGCAGCCCCCGGGCCG CCCCCCGACGCCGGGGCCGCCCCTGTCCGACGTCTCCCGAGTGTCGCGCCGCCCAGCCTG GGAGGCGCGGTGGCCGGTGCGGACCGGGCACTGCGGGAGGCACCTCTCGGCCTCCGAGCG GCCCCTGTCGCCCGCGCGCTGTCACTACAGCTCCTTTCCTCGAGCCGACCGATCCGGCCG CCCCTTCCTCCCGCTCTTCCCGGAGCTGGAGGACCTGCCGCTGCTCGGTCCGGAGCAGCT GGCCCGGCGGGAGGCCCTGCTGCACGCGGCCTGGGCCCGGGGCTCGCGCCCGCGTCACGC TTCCCTGCCCAGCTCCGTGGCCGAGGCCTTCGCTCGGCCCAGCTCGCTGCCCGCTGGGTG CACCGGCCCCGCCTGCGCCCGCCCCGACGGCCACTCGGCCTGCAGGCGCTTGGCGCAGGC GCAGTCAATGTGCTTGCCGATCTACCGGGAGGCCTGCCAGGAGGGCGAGCAGGCAGGGGC CCCCGCCTGGCAGCACAGACAGCACGTCTGCCTGCACGCCCACGCCCACCTGCCATTTTG CTGGGGGGCTGTCTGTCCTCACCTTCCACCCTGTGCCAGCCACGGCTCCTGGCTCTCCGG GGCCTGGGGGCCTCTGGGGCACAGGGGCAGGACTCTGGGGCTGGGCACAGGCTACAGAGA CAGTGGGGGACTGGACGAGATCAGCAGGGTAGCCCGTGGGACGCAAGGCTTCCCGGGACC CTGCACCTGGAGACGGATCTCCAGTCTGGAGTCAGAAGTGTGAGTTATCAGCCACTCAGG CTCCGAGCCAGCTGGATTCTCTGCCTGCCACTGTCAGGGTTAAGCGGCAGGCAGGATTGG GCTTTTCTGGCTTCTACCATGAAATCCTGGCCATGGGACCCCAGTGACAGATGATGTCTT CCATGGTCATCAGTGACCTCAGTAGCCTCAAATCATGGTGAGGGCTGGGCTTTTGCTGTC CTCTTCTCACGCAGAGTTC >OriGene 5' read for NM_000835 unedited
GGGGTTTTGGGGAGGTTTGGCATTTGTNATACNACTCATATAGGCGGCCGCGATTCATGG GTGGGGCCCTGGGGCCGGCCCTGTTGCTCACCTCGCTCTTCGGTGCCTGGGCAGGGCTGG GTCCGGGGCAGGGCGAGCAGGGCATGACGGTGGCCGTGGTGTTTAGCAGCTCAGGGCCGC CCCAGGCCCAGTTCCGTGCCCGCCTCACCCCCCAGAGCTTCCTGGACCTACCCCTGGAGA TCCAGCCGCTCACAGTTGGGGTCAACACCACCAACCCCAGCAGCCTCCTCACCCAGATCT GCGGCCTCCTGGGTGCTGCCCACGTCCACGGCATTGTCTTTGAGGACAACGTGGACACCG AGGCGGTGGCCCAGATCCTTGACTTCATCTCCTCCCAGACCCATGTGCCCATCCTCAGCA TCAGCGGAGGCTCTGCTGTGGTCCTCACCCCCAAGGAGCCGGGCTCCGCCTTCCTGCAGC TGGGCGTGTCCCTGGAGCAGCAGCTGCAGGTGCTGTTCAAGGTGCTGGAAGAGTACGACT GGAGCGCCTTCGCCGTCATCACCAGCCTGCACCCGGGCCACGCGCTCTTCCTGGAGGGCG TGCGCGCCGTCGCCGACGCCAGCCACGTGAGTTGGCGGCTGCTGGACGTGGTCACGCTGG AGCTGGGCCCGGGAGGGCCGCGCGCGCGCACGCAGCGCCTGCTGCGCCAGCTCGACGCGC CCGTGTTTGTGGCCTACTGCTCGCGCGAGGAGGCCGAGGTGCTCTTCGCCGAGGCGGCGC ANGGCCGTCTGGTGGGGCCCGGCCACGTGTGGCTGGTGCCCAACCTGGCGCTGGGCAGCA CCGATGCGCCCCCCGCCACCTTTCCCCGTGGCCTCATCAGCGTCGTCACCGAAAGCTGG >OriGene 3' genomic read for NM_000835 unedited
GGGTTTTGGCCGCCCCATTGGANGATGGCACTTCCCAGGNCCAGNAAAGCACTGGGGNAG GGTCACAGGGATGCCACCCGGGTTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCT AGATGCATGCTCGAGCGGCCGCCAGTGTGATGGATATCTGCAGAATTCGCCCTTGAACTC TGCGTGAGAAGAGGACAGCAAAAGCCCAGCCCTCACCATGATTTGAGGCTACTGAGGTCA CTGATGACCATGGAAGACATCATCTGTCACTGGGGTCCCATGGCCAGGATTTCATGGTAG AAGCCAGAAAAGCCCAATCCTGCCTGCCGCTTAACCCTGACAGTGGCAGGCAGAGAATCC AGCTGGCTCGGAGCCTGAGTGGCTGATAACTCACACTTCTGACTCCAGACTGGAGATCCG TCTCCAGGTGCAGGGTCCCGGGAAGCCTTGCGTCCCACGGGCTACCCTGCTGATCTCGTC CAGTCCCCCACTGTCTCTGTAGCCTGTGCCCAGCCCCAGAGTCCTGCCCCTGTGCCCCAG AGGCCCCCAGGCCCCGGAGAGCCAGGAGCCGTGGCTGGCACAGGGTGGAAGGTGAGGACA GACAGCCCCCCAGCAAAATGGCAGGTGGGCGTGGGCGTGCAGGCAGACGTGCTGTCTGTG CTGCCAGGCGGGGGCCCCTGCCTGCTCGCCCTCCTGGCAGGCCTCCCGGTAGATCGGCAA GCACATTGACTGCGCCTGCGCCAAGCGCCTGCAGGCCGAGTGGCCGTCGGGGCGGGCGCA NGCGGNGCCCGTGCACCCAGCGGGCAGCGAGCTGGGCCGAGCGAAGGCCTNCGCCACGGA GCTGGGCAGGNAAGCGTGACGCGGGCGCGAGCCCCGGGCCCAGCCGCGTGCAGCATGCA |
| Restriction Sites | Please inquire |
| ACCN | NM_000835 |
| Insert Size | 3900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000835.3, NP_000826.2 |
| RefSeq Size | 4298 bp |
| RefSeq ORF | 3702 bp |
| Locus ID | 2905 |
| UniProt ID | Q14957 |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Long-term potentiation, Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
NYX-2925 is a novel NMDA receptor-specific spirocyclic-β-lactam that modulates synaptic plasticity processes associated with learning and memory
,Khan, MA;Houck, DR;Gross, AL;Zhang, XL;Cearley, C;Madsen, TM;Kroes, RA;Stanton, PK;Burgdorf, J;Moskal, JR;,
Int. J. Neuropsychopharmacol.2017
,PubMed ID 29099938
[GRIN2C]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211423 | GRIN2C (Myc-DDK-tagged)-Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C) |
CNY 12,880.00 |
|
| RC211423L1 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), Myc-DDK-tagged |
CNY 15,280.00 |
|
| RC211423L2 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), mGFP tagged |
CNY 14,160.00 |
|
| RC211423L3 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), Myc-DDK-tagged |
CNY 14,160.00 |
|
| RC211423L4 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), mGFP tagged |
CNY 15,280.00 |
|
| RG211423 | GRIN2C (tGFP-tagged) - Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C) |
CNY 14,480.00 |
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