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CD1 (CD1D) (NM_001766) Human Untagged Clone
CAT＃: SC128240
CD1D (untagged)-Human CD1d molecule (CD1D)
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD1A; R3; R3G1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001766 edited
ATGGGGTGCCTGCTGTTTCTGCTGCTCTGGGCGCTCCTCCAGGCTTGGGGAAGCGCTGAA GTCCCGCAAAGGCTTTTCCCCCTCCGCTGCCTCCAGATCTCGTCCTTCGCCAATAGCAGC TGGACGCGCACCGACGGCTTGGCGTGGCTGGGGGAGCTGCAGACGCACAGCTGGAGCAAC GACTCGGACACCGTCCGCTCTCTGAAGCCTTGGTCCCAGGGCACGTTCAGCGACCAGCAG TGGGAGACGCTGCAGCATATATTTCGGGTTTATCGAAGCAGCTTCACCAGGGACGTGAAG GAATTCGCCAAAATGCTACGCTTATCCTATCCCTTGGAGCTCCAGGTGTCCGCTGGCTGT GAGGTGCACCCTGGGAACGCCTCAAATAACTTCTTCCATGTAGCATTTCAAGGAAAAGAT ATCCTGAGTTTCCAAGGAACTTCTTGGGAGCCAACCCAAGAGGCCCCACTTTGGGTAAAC TTGGCCATTCAAGTGCTCAACCAGGACAAGTGGACGAGGGAAACAGTGCAGTGGCTCCTT AATGGCACCTGCCCCCAATTTGTCAGTGGCCTCCTTGAGTCAGGGAAGTCGGAACTGAAG AAGCAAGTGAAGCCCAAGGCCTGGCTGTCCCGTGGCCCCAGTCCTGGCCCTGGCCGTCTG CTGCTGGTGTGCCATGTCTCAGGATTCTACCCAAAGCCTGTATGGGTGAAGTGGATGCGG GGTGAGCAGGAGCAGCAGGGCACTCAGCCAGGGGACATCCTGCCCAATGCTGACGAGACA TGGTATCTCCGAGCAACCCTGGATGTGGTGGCTGGGGAGGCAGCTGGCCTGTCCTGTCGG GTGAAGCACAGCAGTCTAGAGGGCCAGGACATCGTCCTCTACTGGGGTGGGAGCTACACC TCCATGGGCTTGATTGCCTTGGCAGTCCTGGCGTGCTTGCTGTTCCTCCTCATTGTGGGC TTTACCTCCCGGTTTAAGAGGCAAACTTCCTATCAGGGCGTCCTGTGA >OriGene 5' read for NM_001766 unedited
NTTTGGGGAGTCAAAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGG GTGAGGTGATGTCAAAAGGTAGACACCAGGGCTAGAGGGCGCATAATCTTGCAGGCCGTG CTAATGATTTTGTTTTCTACCCAAGAATGCTACTTCAGGAGATCAGTCAAAAGGTTAGGG TGATGGTGACGGTGGAAATATAGAAAAAGGAATTTATTCAAGAGGTATTCAAAAAGAAGT GAAATAGAGATGAGTTGGAGATAGATTGGATAAAAAGAGTGAGGGAGAGGGAGGTGTCAG GCTGCAGCCCAGGTTCTGAGTTGCCAAAGAGGAGTCTTTTCCTCCAGGAAATTGAGACAC GCCGGTTGTGAAACCTACTGAAGTGAGCGGCGGCGCCAGGATTCCTGGGACCCCGACCTC TTTGCAGCTCGCACAGCTAAGGGCGAGGGCGCCCTTCGGCAGAAGCAGCAAACCGCCGGC AAGCCCAGCGAGGAGGGCTGCCGGGGTCTGGGCTTGGGAATTGGCTGGCACCCAGCGAAN AGGGACGTGAGCTGAGCGGGCGGGGAAGAGAGTGCGCAGGTCAGAAGGCGGCGCGCAGCG GCGCTCCGCGAGGTCCCCACGCCCGGCGATATGGGGTGCCTGCTGTTTCTGCTGCTCTGG GCGCTCCTCCAGGCTTGGGGAAGCGCTGAAGTCCCGCAAAGGCTTTTCCCCCTNCGCTGC CTNCAGATCTCGTCCTTTGGCCATAGCAGCTGGACGCGCACCGACGCTTGGCCGTGCTGG GGAAGCTGCANACGCACAGCTGGAGCACGACTCGGACACCGTCCGGTCTCTGGACCCTGG TCCCAGGGCACGTCCACCGACAACAATGGGAGACGCTTCACATTATTTTCGGTTTTATTC GAGCACTTCN >Forward primer walk for NM_001766 unedited
NTTTTTCTTGGCCCCGATCCTGGCCCTGGCCGTCTGCTGCTGGTGTGCCATGTCTCAGGA TTCTACCCAAAGCCTGTATGGGTGAAGTGGATGCGGGGTGAGCAGGAGCAGCAGGGCACT CAGCCAGGGGACATCCTGCCCAATGCTGACGAGACATGGTATCTCCGAGCAACCCTGGAT GTGGTGGCTGGGGAGGCAGCTGGCCTGTCCTGTCGGGTGAAGCACAGCAGTCTAGAGGGC CAGGACATCGTCCTCTACTGGGGTGGGAGCTACACCTCCATGGGCTTGATTGCCTTGGCA GTCCTGGCGTGCTTGCTGTTCCTCCTCATTGTGGGCTTTACCTCCCGGTTTAAGAGGCAA ACTTCCTATCAGGGCGTCCTGTGACTCGCCTTGCCACATCTGTGTCTCTGGAACCCAGGA CCTCTGGACCTCAGGTTCCCAAGACTTCAGTCCTGGTCTGCTCAGGAATTGAAGATGTAA GGAATTGAAGATAGGAGAGATACCTTGAAAAAGTAGAGAACAGTCATGAGGCAGCTTTCA TCACACCCTTTTAACATTTATCTAAAAGAATTTAAATTCTTTTTCAAAAATTACACTACA AGTTTATAAGCCCAAATGGCTCTGTGAAATCAGAAGTGCAAAGGTGTGCAAACTTGTATC TGAAGACCTACCAGGGACAAGCAGGTAAGAGCTGATGTGAGTGTGTGTGATGGGATCTGT AAGGAACTGNGACACACATGTCCTATCCAAAGGAATCAGCTGCAGCTGCTTGTTGTCAAG TATAAAGTCAGGACCTGGCTTGGGCTTNACCGTTTTTCAAGAAACTGGAAATCTGGATTT TCAGCGAACATGCCCTGATTTAAAAGGNTGACTCAGTTTTTACAAATACTATGTGNGACA CCTCANATACTACCTACTGC |
| Restriction Sites | Please inquire |
| ACCN | NM_001766 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001766.3, NP_001757.1 |
| RefSeq Size | 3795 bp |
| RefSeq ORF | 1008 bp |
| Locus ID | 912 |
| UniProt ID | P15813 |
| Domains | IGc1 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Hematopoietic cell lineage |
| Gene Summary | This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy
,Hara, A;Koyama-Nasu, R;Takami, M;Toyoda, T;Aoki, T;Ihara, F;Kobayashi, M;Hirono, S;Matsutani, T;Nakayama, T;Iwadate, Y;Motohashi, S;,
Cancer Immunol Immunother
,PubMed ID 33128583
[CD1D]
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Vaccination with Antigen-Transfected, NKT Cell Ligand–Loaded, Human Cells Elicits Robust In Situ Immune Responses by Dendritic Cells
,Kanako Shimizu, Takuya Mizuno, Jun Shinga, Miki Asakura, Kazuhiro Kakimi, Yasuyuki Ishii, Kenichi Masuda, Tomoji Maeda, Hidetoshi Sugahara, Yusuke Sato, Hirokazu Matsushita, Keigo Nishida, Kenichi Hanada, Jan Dorrie, Niels Schaft, Kara Bickham, Hisashi Koike, Tsuyoshi Ando, Ryozo Nagai, and Shin-ichiro Fujii,
Cancer Res., Jan 2013; 73: 62 - 73.
[CD1d]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206613 | CD1D (Myc-DDK-tagged)-Human CD1d molecule (CD1D) |
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| RC206613L1 | Lenti ORF clone of Human CD1d molecule (CD1D), Myc-DDK-tagged |
CNY 5,890.00 |
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| RC206613L2 | Lenti ORF clone of Human CD1d molecule (CD1D), mGFP tagged |
CNY 5,890.00 |
|
| RC206613L3 | Lenti ORF clone of Human CD1d molecule (CD1D), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206613L4 | Lenti ORF clone of Human CD1d molecule (CD1D), mGFP tagged |
CNY 5,890.00 |
|
| RG206613 | CD1D (tGFP-tagged) - Human CD1d molecule (CD1D) |
CNY 4,370.00 |
