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Artemis (DCLRE1C) (NM_022487) Human Untagged Clone
CAT＃: SC127058
DCLRE1C (untagged)-Human DNA cross-link repair 1C (DCLRE1C), transcript variant b
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | A-SCID; DCLREC1C; RS-SCID; SCIDA; SNM1C |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127058 sequence for NM_022487 edited (data generated by NextGen Sequencing)
ATGAAGCATCAGGAGAGGTTTTTATTTCAGGGCAATAATGGAACTGTCCTGTACACAGGA GACTTCAGATTGGCGCAAGGAGAAGCTGCTAGAATGGAGCTTCTGCACTCCGGGGGCAGA GTCAAAGACATCCAAAGTGTATATTTGGATACTACGTTCTGTGATCCAAGATTTTACCAA ATTCCAAGTCGGGAGGAGTGTTTAAGTGGAGTCTTAGAGCTGGTCCGAAGCTGGATCACT CGGAGCCCGTACCATGTTGTTTGGCTGAACTGCAAAGCGGCTTATGGCTATGAATATCTG TTCACCAACCTTAGTGAAGAATTAGGAGTCCAGGTTCATGTGAATAAGCTAGACATGTTT AGGAACATGCCTGAGATCCTTCATCATCTCACAACAGACCGCAACACTCAGATCCATGCA TGCCGGCATCCCAAGGCAGAGGAATATTTTCAGTGGAGCAAATTACCCTGTGGAATTACT TCCAGAAATAGAATTCCACTCCACATAATCAGCATTAAGCCATCCACCATGTGGTTTGGA GAAAGGAGCAGAAAAACAAATGTAATTGTGAGGACTGGAGAGAGTTCATACAGAGCTTGT TTTTCTTTTCACTCCTCCTACAGTGAGATTAAAGATTTCTTGAGCTACCTCTGTCCTGTG AACGCATATCCAAATGTCATTCCAGTTGGCACAACTATGGATAAAGTTGTCGAAATCTTA AAGCCTTTATGCCGGTCTTCCCAAAGTACGGAGCCAAAGTATAAACCACTGGGAAAACTG AAGAGAGCTAGAACAGTTCACCGAGACTCAGAGGAGGAAGATGACTATCTCTTTGATGAT CCTCTGCCAATACCTTTAAGGCACAAAGTTCCATACCCGGAAACTTTTCACCCTGAGGTA TTTTCAATGACTGCAGTATCAGAAAAGCAGCCTGAAAAACTGAGACAAACCCCAGGATGC TGCAGAGCAGAGTGTATGCAGAGCTCTCGTTTCACAAACTTTGTAGATTGTGAAGAATCC AACAGTGAAAGTGAAGAAGAAGTAGGAATCCCAGCTTCACTGCAAGGAGATCTGGGCTCT GTACTTCACCTGCAAAAGGCTGATGGGGATGTACCCCAGTGGGAAGTATTCTTTAAAAGA AATGATGAAATCACAGATGAGAGTTTGGAAAACTTCCCTTCCTCCACAGTGGCAGGGGGA TCTCAGTCACCAAAGCTTTTCAGTGACTCTGATGGAGAATCAACTCACATCTCCTCCCAG AATTCTTCCCAGTCAACACACATAACAGAACAAGGAAGTCAAGGCTGGGACAGCCAATCT GATACTGTTTTGTTATCTTCCCAAGAGAGAAACAGTGGGGATATTACTTCCTTGGACAAA GCTGACTACAGACCAACAATCAAAGAGAATATTCCTGCCTCTCTCATGGAACAAAATGTA ATTTGCCCAAAGGATACTTACTCTGATTTGAAAAGCAGAGATAAAGATGTGACAATAGTT CCTAGTACTGGAGAACCAACTACTCTAAGCAGTGAGACACATATACCCGAGGAAAAAAGT TTGCTAAATCTTAGCACAAATGCAGATTCCCAGAGCTCTTCTGATTTTGAAGTTCCCTCA ACTCCAGAAGCTGAGTTACCTAAACGAGAGCATTTACAATATTTATATGAGAAGCTGGCA ACTGGTGAGAGTATAGCAGTCAAAAAAAGAAAATGCTCACTCTTAGATACCTAA Clone variation with respect to NM_022487.2 261 g=>t >OriGene 5' read for NM_022487 unedited
TTGTAATCCGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGGCGGTTTTGGGGTCC CGGACTCTGGGATCGGCGGCGCTATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAA CTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTCCTGTCCC ACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGT GCAGATGAGGAAACTGAGGAACCAGAGAGGTTAAATTAGTTGCCCAGTGTCACACAGCCA GTAAGTGGCAGGACCAGGATTCCAGCCAGCTTGAAGGTTTATCTATACTGTTCACCTGTG ACTAAGGAGTTGTTGTTAACGAGCCCGAAATACAGATCTTGGAAGAAACGAATTATATCT ATTGAAATCGAGACTCCTACCCAGATATCTTTAGTGGATGAAGCATCAGGAGAGAAGGAA GAGATTGTTGTGACTCTCTTACCAGCTGGTCACTGTCCGGGATCAGTTAAGTTTTTATTT CAGGGCAATAATGGAACTGTCCTGTACACAGGAGACTTCAGATTGGCGCAAGGAGAAACT GCTAGAATGGAGCTTCTGCACTCCGGGGGCAGAGTCAAAGACATCCAAAGTGTATACTTG GATACTACGTTCTGTGATCCCCGAATTACCAAATTCCAAGTCCGGAGGCGTGGTTAAGTG GGAGTCTTACAGCTGGTCCGAAGCTGGATCACTCGGAGCCCGTACCATGTTGNACGGGCT GAACTGCAAACCGCCTTATTGCTTATGAATTCTTGTTCCCCACCCTTATGAACTATTAGG ATCCAGGGTCTTGTGAATAAACTACAATGTTCAGGAACTTGCTGAATATCCTTATTATTT TAAACAGA >OriGene 3' read for NM_022487 unedited
TTACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTAAGTAGAGACACA TTTCACTGTGTTGGCCAGGCTGGTGTCGAACTCCTGGGCTCAAGCCATTGCCCACCTCAA AGTGCTGGGATTACAAGTGTGAGCCACCACACCCAACCAGGTTATTTGAACATTTTTAAG TACTGTATTTTCTCTATTGTAATATTGACTGTCATCTCTGTGCAGGTTTTTTAGTGGTTG CTCTAGGTTGAAACGCTTTGAATTCTTAGGTATCTAAGAGTGAGCATTTTCTTTTTTTGA CTGCTATACTCTCACCAGTTGCCAGCTTCTCATATAAATATTGTAAATGCTCTCGTTTAG GTAACTCAGCTTCTGGAGTTGAGGGAACTTCAAAATCAGAAGAGCTCTGGGAATCTGCAT TTGTGCTAAGATTTAGCAAACTTTTTTCCTCGGGTATATGTGTCTCACTGCTTAGAGTAG TTGGTTCTCCAGTACTAGGAACTATTGTCACATCTTTATCTCTGCTTTTCAAATCAGAGT AAGTATCCTTTGGGCAAATTACATTTTGTTCCATGAGAGAGGCAGGAATATTCTCTTTGA TTGTTGGTCTGTAGTCAGCTTTGTCCAAGGAAGTAATATCCCCACTGTTTCTCTCTTGGG AAGATAACANAACAGTATCAGATTGGCTGTCCCAGCCTTGACTTCCTTGTTCTGTTATGT GTGTTGACTGGGAAGAATTCTGGGAGGAGATGTGAGTTGATTCTCCATCAGAGTCACCTG AAAGCCTTGGTGACTGAGATCCCCCTGCCACTGTGGAGGAAGGNAAAGTTTTCAACTCTC ATCTGGGATTTATCATTCCTTTTAAGAAACTNCCACTGGGGTACATCCCATCAGCCTTTG CAGTGGAGTACAAAGCCAGATCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_022487 |
| Insert Size | 2440 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022487.1, NP_071932.1 |
| RefSeq Size | 2636 bp |
| RefSeq ORF | 1734 bp |
| Locus ID | 64421 |
| UniProt ID | Q96SD1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Cell cycle, Non-homologous end-joining, Primary immunodeficiency |
| Gene Summary | This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Transcript Variant: This variant (b, also called V3) lacks an exon in the 5' coding region and initiates translation at an alternate downstream start codon, compared to variant a. It encodes isoform b, which has a shorter and distinct N-terminus compared to variant a. Variants b, e, and g encode the same isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203407 | DCLRE1C (Myc-DDK-tagged)-Human DNA cross-link repair 1C (DCLRE1C), transcript variant b |
CNY 3,990.00 |
|
| RC203407L1 | Lenti ORF clone of Human DNA cross-link repair 1C (DCLRE1C), transcript variant b, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203407L2 | Lenti ORF clone of Human DNA cross-link repair 1C (DCLRE1C), transcript variant b, mGFP tagged |
CNY 5,890.00 |
|
| RC203407L3 | Lenti ORF clone of Human DNA cross-link repair 1C (DCLRE1C), transcript variant b, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203407L4 | Lenti ORF clone of Human DNA cross-link repair 1C (DCLRE1C), transcript variant b, mGFP tagged |
CNY 5,890.00 |
|
| RG203407 | DCLRE1C (tGFP-tagged) - Human DNA cross-link repair 1C (DCLRE1C), transcript variant b |
CNY 4,370.00 |
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