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KCNE1 (NM_000219) Human Untagged Clone
CAT＃: SC126888
KCNE1 (untagged)-Human potassium voltage-gated channel, Isk-related family, member 1 (KCNE1), transcript variant 2
CNY 3,990.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ISK; JLNS; JLNS2; LQT2/5; LQT5; MinK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites | Please inquire |
| ACCN | NM_000219 |
| Insert Size | 390 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000219.2, NP_000210.2 |
| RefSeq Size | 3570 bp |
| RefSeq ORF | 390 bp |
| Locus ID | 3753 |
| UniProt ID | P15382 |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| Gene Summary | The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) is the longest transcript. All variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
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Single-channel basis for the slow activation of the repolarizing cardiac potassium current, IKs
,Daniel Werry, Jodene Eldstrom, Zhuren Wang, and David Fedida,
PNAS, Mar 2013; 110: E996 - E1005.
[KCNE1]
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Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of Iks
,Jodene Eldstrom, Hongjian Xu, Daniel Werry, Congbao Kang, Matthew E. Loewen, Amanda Degenhardt, Shubhayan Sanatani, Glen F. Tibbits, Charles Sanders, and David Fedida,
J. Gen. Physiol., Apr 2010; 135: 433 - 448
[KCNE1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206049 | KCNE1 (Myc-DDK-tagged)-Human potassium voltage-gated channel, Isk-related family, member 1 (KCNE1), transcript variant 2 |
CNY 1,200.00 |
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| RC206049L3 | Lenti-ORF clone of KCNE1 (Myc-DDK-tagged)-Human potassium voltage-gated channel, Isk-related family, member 1 (KCNE1), transcript variant 2 |
CNY 5,890.00 |
|
| RC206049L4 | Lenti-ORF clone of KCNE1 (mGFP-tagged)-Human potassium voltage-gated channel, Isk-related family, member 1 (KCNE1), transcript variant 2 |
CNY 5,890.00 |
|
| RG206049 | KCNE1 (tGFP-tagged) - Human potassium voltage-gated channel, Isk-related family, member 1 (KCNE1), transcript variant 2 |
CNY 2,800.00 |
