AKR1B1 (NM_001628) Human Untagged Clone
CAT#: SC126774
AKR1B1 (untagged)-Human aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ADR; ALDR1; ALR2; AR |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC126774 sequence for NM_001628 edited (data generated by NextGen Sequencing)
ATGGCAAGCCGTCTCCTGCTCAACAACGGCGCCAAGATGCCCATCCTGGGGTTGGGTACC TGGAAGTCCCCTCCAGGGCAGGTGACTGAGGCCGTGAAGGTGGCCATTGACGTCGGGTAC CGCCACATCGACTGTGCCCATGTGTACCAGAATGAGAATGAGGTGGGGGTGGCCATTCAG GAGAAGCTCAGGGAGCAGGTGGTGAAGCGTGAGGAGCTCTTCATCGTCAGCAAGCTGTGG TGCACGTACCATGAGAAGGGCCTGGTGAAAGGAGCCTGCCAGAAGACACTCAGCGACCTG AAGCTGGACTACCTGGACCTCTACCTTATTCACTGGCCGACTGGCTTTAAGCCTGGGAAG GAATTTTTCCCATTGGATGAGTCGGGCAATGTGGTTCCCAGTGACACCAACATTCTGGAC ACGTGGGCGGCCATGGAAGAGCTGGTGGATGAAGGGCTGGTGAAAGCTATTGGCATCTCC AACTTCAACCATCTCCAGGTGGAGATGATCTTAAACAAACCTGGCTTGAAGTATAAGCCT GCAGTTAACCAGATTGAGTGCCACCCATATCTCACTCAGGAGAAGTTAATCCAGTACTGC CAGTCCAAAGGCATCGTGGTGACCGCCTACAGCCCCCTCGGCTCTCCTGACAGGCCCTGG GCCAAGCCCGAGGACCCTTCTCTCCTGGAGGATCCCAGGATCAAGGCGATCGCAGCCAAG CACAATAAAACTACAGCCCAGGTCCTGATCCGGTTCCCCATGCAGAGGAACTTGGTGGTG ATCCCCAAGTCTGTGACACCAGAACGCATTGCTGAGAACTTTAAGGTCTTTGACTTTGAA CTGAGCAGCCAGGATATGACCACCTTACTCAGCTACAACAGGAACTGGAGGGTCTGTGCC TTGTTGAGCTGTACCTCCCACAAGGATTACCCCTTCCATGAAGAGTTTTGA Clone variation with respect to NM_001628.2 >OriGene 5' read for NM_001628 unedited
GAACACCATTACTATAGGCGGCCGCGCAATTCGCACGAGGCCTCGTGCCGAATTCGGCAC GAGGCACCGTACTGGGCGGGGGTCTGGGGAGCGCAGCAGCCATGGCAAGCCGTCTCCTGC TCAACAACGGCGCCAAGATGCCCATCCTGGGGTTGGGTACCTGGAAGTCCCCTCCAGGGC AGGTGACTGAGGCCGTGAAGGTGGCCATTGACGTCGGGTACCGCCACATCGACTGTGCCC ATGTGTACCAGAATGAGAATGAGGTGGGGGTGGCCATTCAGGAGAAGCTCAGGGAGCAGG TGGTGAAGCGTGAGGAGCTCTTCATCGTCAGCAAGCTGTGGTGCACGTACCATGAGAAGG GCCTGGTGAAAGGAGCCTGCCAGAAGACACTCAGCGACCTGAAGCTGGACTACCTGGACC TCTACCTTATTCACTGGCCGACTGGCTTTAAGCCTGGGAAGGAATTTTTCCCATTGGATG AGTCGGGCAATGTGGTTCCCAGTGACACCAACATTCTGGACACGTGGGCGGCCATGGAAG AGCTGGTGGATGAAGGGCTGGTGAAAGCTATTGGCATCTCCAACTTCAACCATCTCCAGG TGGAGATGATCTTAAACAAACCTGGCTTGAAGTATAAGCCTGCAGTTAACCAGATTGAGT GCCACCCATATCTCACTCAGGAGAAGTTAATCCAGTACTGCCAGTCCAAAGGCATCGTGG TGACCGCCTACAGCCCCCTCGGCTCTTCTGACAGGCCCTGNGCCAAGCCCCGAGACCCTT CTCTTNCTGGAGATCCCAGNATCAAGGCGATCGCAGCCAAGCACAATAAACTACANGCCC AGTCCTTGATCCGGNTCCCCATGCAGNAGAACTTGNTGGNTGACCA >OriGene 3' read for NM_001628 unedited
ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTACACAAAAGCACTTTT TATTTGAGGCAAAGAGAAGTCTTGCTGAAAGGATTCCAGTTCCAAGCAGTCAAAACTCAA CCGTTAGTGGCACTATTTTGACCTGGTAGATTTTGCTTCTCTTTGGTCAGAAAAGGGTAT TCAGGTTGTACTTTCCCCAGCAGGGTAGAAAGAAGGGCAAAGCAAACTGGAAGAGACTTC TACTCTACTGACAGGGCTCTTGAGATCCAACATCAAGCTAGACACGCCCTCGCTGGCCAC TCTACAGGTTGCTGTCCCACTGCTGAGTGACACAGGCCATACTACATTTGCAAGGAAAAA AATGAGGCAAGAAACACAGGTATAGGTCACTTGGGGACGAGCAGGCAACCACAGCTTCAA AACTCTTCATGGAAGGGGTAATCCTTGTGGGAGGTACAGCTCAACAAGGCACAGACCCTC CAGTTCCTGTTGTAGCTGAGTAAGGTGGTCATATCCTGGCTGCTCAGTTCAAAGTCAAAG ACCTTAAAGTTCTCAGCAATGCGTTCTGGTGTCACAGACTTGNGGATCACCACCAAGTTC CTCTGCATGGGGAACCGGATCAGGACCTGGGCTGTANGTTTATTGTGCTTGGCTGCGATC GCCTTGATCCTGGGATCCTCCAGGAGAAGAAGGTCCTCGGGCTTGGCCANGGCCTGTCAA GAAACCGAGGGGGCTGTAAGCGGCACCACGATGCTTTGGACTGGCAGACTGGATAACTCT CCTGATGAGAATGGGGGGACTAATCTGGTACTGCAGCTTATACTTAACCCAGTTTGTTAG ATCTCTCCCCTGAAAGGTGAATTGGAATCCCATCCTTTCCAC |
Restriction Sites | NotI-NotI |
ACCN | NM_001628 |
Insert Size | 1530 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001628.2, NP_001619.1 |
RefSeq Size | 1416 bp |
RefSeq ORF | 951 bp |
Locus ID | 231 |
UniProt ID | P15121 |
Domains | aldo_ket_red |
Protein Families | Druggable Genome |
Protein Pathways | Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Pyruvate metabolism |
Gene Summary | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009] Transcript Variant: This variant (1) encodes isoform 1. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC200504 | AKR1B1 (Myc-DDK-tagged)-Human aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1) |
CNY 2,400.00 |
|
RC200504L3 | Lenti ORF clone of Human aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), Myc-DDK-tagged |
CNY 4,800.00 |
|
RC200504L4 | Lenti ORF clone of Human aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), mGFP tagged |
CNY 4,800.00 |
|
RG200504 | AKR1B1 (tGFP-tagged) - Human aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1) |
CNY 4,370.00 |
|
SC320670 | AKR1B1 (untagged)-Human aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1) |
CNY 2,400.00 |