AKR1B1 (NM_001628) Human Untagged Clone

CAT#: SC126774

AKR1B1 (untagged)-Human aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1)



  "NM_001628" in other vectors (5)

CNY 2,400.00

CNY 2,950.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


Anti-AKR1B1 Rabbit Polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ADR; ALDR1; ALR2; AR
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC126774 sequence for NM_001628 edited (data generated by NextGen Sequencing)
ATGGCAAGCCGTCTCCTGCTCAACAACGGCGCCAAGATGCCCATCCTGGGGTTGGGTACC
TGGAAGTCCCCTCCAGGGCAGGTGACTGAGGCCGTGAAGGTGGCCATTGACGTCGGGTAC
CGCCACATCGACTGTGCCCATGTGTACCAGAATGAGAATGAGGTGGGGGTGGCCATTCAG
GAGAAGCTCAGGGAGCAGGTGGTGAAGCGTGAGGAGCTCTTCATCGTCAGCAAGCTGTGG
TGCACGTACCATGAGAAGGGCCTGGTGAAAGGAGCCTGCCAGAAGACACTCAGCGACCTG
AAGCTGGACTACCTGGACCTCTACCTTATTCACTGGCCGACTGGCTTTAAGCCTGGGAAG
GAATTTTTCCCATTGGATGAGTCGGGCAATGTGGTTCCCAGTGACACCAACATTCTGGAC
ACGTGGGCGGCCATGGAAGAGCTGGTGGATGAAGGGCTGGTGAAAGCTATTGGCATCTCC
AACTTCAACCATCTCCAGGTGGAGATGATCTTAAACAAACCTGGCTTGAAGTATAAGCCT
GCAGTTAACCAGATTGAGTGCCACCCATATCTCACTCAGGAGAAGTTAATCCAGTACTGC
CAGTCCAAAGGCATCGTGGTGACCGCCTACAGCCCCCTCGGCTCTCCTGACAGGCCCTGG
GCCAAGCCCGAGGACCCTTCTCTCCTGGAGGATCCCAGGATCAAGGCGATCGCAGCCAAG
CACAATAAAACTACAGCCCAGGTCCTGATCCGGTTCCCCATGCAGAGGAACTTGGTGGTG
ATCCCCAAGTCTGTGACACCAGAACGCATTGCTGAGAACTTTAAGGTCTTTGACTTTGAA
CTGAGCAGCCAGGATATGACCACCTTACTCAGCTACAACAGGAACTGGAGGGTCTGTGCC
TTGTTGAGCTGTACCTCCCACAAGGATTACCCCTTCCATGAAGAGTTTTGA

Clone variation with respect to NM_001628.2
>OriGene 5' read for NM_001628 unedited
GAACACCATTACTATAGGCGGCCGCGCAATTCGCACGAGGCCTCGTGCCGAATTCGGCAC
GAGGCACCGTACTGGGCGGGGGTCTGGGGAGCGCAGCAGCCATGGCAAGCCGTCTCCTGC
TCAACAACGGCGCCAAGATGCCCATCCTGGGGTTGGGTACCTGGAAGTCCCCTCCAGGGC
AGGTGACTGAGGCCGTGAAGGTGGCCATTGACGTCGGGTACCGCCACATCGACTGTGCCC
ATGTGTACCAGAATGAGAATGAGGTGGGGGTGGCCATTCAGGAGAAGCTCAGGGAGCAGG
TGGTGAAGCGTGAGGAGCTCTTCATCGTCAGCAAGCTGTGGTGCACGTACCATGAGAAGG
GCCTGGTGAAAGGAGCCTGCCAGAAGACACTCAGCGACCTGAAGCTGGACTACCTGGACC
TCTACCTTATTCACTGGCCGACTGGCTTTAAGCCTGGGAAGGAATTTTTCCCATTGGATG
AGTCGGGCAATGTGGTTCCCAGTGACACCAACATTCTGGACACGTGGGCGGCCATGGAAG
AGCTGGTGGATGAAGGGCTGGTGAAAGCTATTGGCATCTCCAACTTCAACCATCTCCAGG
TGGAGATGATCTTAAACAAACCTGGCTTGAAGTATAAGCCTGCAGTTAACCAGATTGAGT
GCCACCCATATCTCACTCAGGAGAAGTTAATCCAGTACTGCCAGTCCAAAGGCATCGTGG
TGACCGCCTACAGCCCCCTCGGCTCTTCTGACAGGCCCTGNGCCAAGCCCCGAGACCCTT
CTCTTNCTGGAGATCCCAGNATCAAGGCGATCGCAGCCAAGCACAATAAACTACANGCCC
AGTCCTTGATCCGGNTCCCCATGCAGNAGAACTTGNTGGNTGACCA
>OriGene 3' read for NM_001628 unedited
ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTACACAAAAGCACTTTT
TATTTGAGGCAAAGAGAAGTCTTGCTGAAAGGATTCCAGTTCCAAGCAGTCAAAACTCAA
CCGTTAGTGGCACTATTTTGACCTGGTAGATTTTGCTTCTCTTTGGTCAGAAAAGGGTAT
TCAGGTTGTACTTTCCCCAGCAGGGTAGAAAGAAGGGCAAAGCAAACTGGAAGAGACTTC
TACTCTACTGACAGGGCTCTTGAGATCCAACATCAAGCTAGACACGCCCTCGCTGGCCAC
TCTACAGGTTGCTGTCCCACTGCTGAGTGACACAGGCCATACTACATTTGCAAGGAAAAA
AATGAGGCAAGAAACACAGGTATAGGTCACTTGGGGACGAGCAGGCAACCACAGCTTCAA
AACTCTTCATGGAAGGGGTAATCCTTGTGGGAGGTACAGCTCAACAAGGCACAGACCCTC
CAGTTCCTGTTGTAGCTGAGTAAGGTGGTCATATCCTGGCTGCTCAGTTCAAAGTCAAAG
ACCTTAAAGTTCTCAGCAATGCGTTCTGGTGTCACAGACTTGNGGATCACCACCAAGTTC
CTCTGCATGGGGAACCGGATCAGGACCTGGGCTGTANGTTTATTGTGCTTGGCTGCGATC
GCCTTGATCCTGGGATCCTCCAGGAGAAGAAGGTCCTCGGGCTTGGCCANGGCCTGTCAA
GAAACCGAGGGGGCTGTAAGCGGCACCACGATGCTTTGGACTGGCAGACTGGATAACTCT
CCTGATGAGAATGGGGGGACTAATCTGGTACTGCAGCTTATACTTAACCCAGTTTGTTAG
ATCTCTCCCCTGAAAGGTGAATTGGAATCCCATCCTTTCCAC
Restriction Sites NotI-NotI     
ACCN NM_001628
Insert Size 1530 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001628.2, NP_001619.1
RefSeq Size 1416 bp
RefSeq ORF 951 bp
Locus ID 231
UniProt ID P15121
Domains aldo_ket_red
Protein Families Druggable Genome
Protein Pathways Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Pyruvate metabolism
Gene Summary This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
Transcript Variant: This variant (1) encodes isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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