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ATG4C (NM_032852) Human Untagged Clone
CAT＃: SC126496
ATG4C (untagged)-Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APG4-C; APG4C; AUTL1; AUTL3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126496 sequence for NM_032852 edited (data generated by NextGen Sequencing)
ATGGAGGCTACAGGAACAGATGAAGTTGACAAGCTAAAAACCAAATTTATATCTGCTTGG AACAACATGAAATATAGTTGGGTGTTGAAAACAAAGACGTATTTTAGTAGAAATTCTCCT GTATTATTGCTTGGAAAATGTTACCATTTTAAATATGAAGATGAAGATAAAACGTTACCT GCAGAGTCGGGATGTACAATAGAGGATCACGTAATTGCAGGAAATGTAGAAGAATTTCGT AAAGATTTCATTTCTAGAATATGGCTGACCTACAGGGAAGAATTCCCTCAAATAGAAGGC TCAGCTTTGACAACAGACTGTGGGTGGGGCTGCACATTGAGAACTGGCCAGATGCTCTTG GCTCAAGGACTCATACTACACTTTCTTGGTAGAGCTTGGACCTGGCCTGATGCTTTGAAT ATTGAAAATTCAGACTCTGAATCATGGACTTCCCACACTGTCAAAAAATTTACTGCATCA TTTGAAGCATCACTTTCAGGGGAAAGAGAATTCAAAACCCCAACAATTTCTCTGAAGGAA ACAATTGGGAAATATTCTGATGATCATGAAATGCGAAATGAAGTTTATCATAGGAAAATC ATCTCTTGGTTTGGTGATTCCCCCTTGGCTCTTTTTGGCTTACATCAACTAATAGAATAT GGAAAGAAGTCTGGGAAAAAAGCAGGAGATTGGTATGGACCAGCTGTGGTTGCTCACATT TTAAGAAAAGCAGTTGAAGAAGCAAGGCATCCTGATTTACAAGGAATAACTATTTATGTT GCACAAGATTGTACAGTTTACAATTCTGATGTAATTGATAAACAGAGTGCTTCCATGACT TCTGATAATGCAGATGACAAAGCTGTTATTATTCTAGTTCCTGTTAGACTTGGTGGAGAA AGAACCAACACCGACTACTTAGAATTTGTGAAGGGTATTTTAAGCCTGGAATATTGTGTG GGTATTATTGGTGGCAAACCTAAACAGTCATATTACTTTGCTGGATTTCAAGATGACAGT TTGATTTACATGGATCCTCATTACTGCCAATCTTTTGTAGATGTCAGCATAAAGGATTTC CCTCTTGAGACATTCCACTGCCCTTCTCCCAAAAAGATGTCTTTTCGAAAAATGGATCCC AGCTGTACAATAGGATTTTACTGTCGAAATGTTCAGGACTTCAAACGAGCTTCTGAAGAA ATCACCAAGATGCTGAAATTTTCTTCTAAGGAGAAATATCCCTTATTTACTTTTGTAAAT GGTCATTCCAGAGACTATGATTTTACATCTACTACAACCAATGAAGAAGACCTTTTTTCA GAGGATGAAAAGAAACAATTAAAAAGATTTAGCACGGAAGAGTTTGTCTTGCTTTAA Clone variation with respect to NM_032852.3 >OriGene 5' read for NM_032852 unedited
TCCTATAGGGCGGCCGCGAATTCGGCACGAGGCGGCGCTGAGGTCGGAACGTCTGCGTGT GTGCGGGCTGGTTTTGCGGCGGCTGCTGCTAGAGCTGGAGCATTTGCCGGGTTGGTGGCT CCTGCACATTTTTACAGTTCTCCAGTCCTTCTCTTTCGTCAGTATAAAAGATTAAACTCT ACAGAAGAATGCAATCAAGTGATGGCTTTTCCTTTATAATTTGAATATGGAGGCTACAGG AACAGATGAAGTTGACAAGCTAAAAACCAAATTTATATCTGCTTGGAACAACATGAAATA TAGTTGGGTGTTGAAAACAAAGACGTATTTTAGTAGAAATTCTCCTGCCTTATTGCTCGG AAAACGTCACCATTTTAAATATGAAGATGAAGATAAACGTTACCTGCAGAGTTCGGATGT ACAATAGAGGATCACGTAATTGCAAGAAATGTACAAAAATTTCGCAAAGATTTTATTTCT AGAATTTGGGTTGACCTACAGGGAAAAAATCCCTTCAATAGAAGGCGCTAGCTTTGAAAA CAAACTGGGGGTGGGGCTGCCCATTGACAACTGCCCTATGCTCTTGGCTTCAAGACCCAC ACCCACCTTCCCTGGGACACCCTTGACCCCTGCCTGATCCCCTTCACACTTCAAACTTAA ACTCTAAATCAGGGCCTCCCACCCGGTAAAAAATTCATTGGACTATTGAAACCTCCCTTT CAGGGGAAAGAAATTAAACCCCACAATTTTTTTGAAGAAAAACTTGGAAAATTCTTAGAA CATCACTCGACATGACCTTTTTATGAAATACTTCCTTGGTTGCCGACCCCCCTGCCTCCT TTTGCCTCCCCCACCATAACTCCTGTAACAATCCCGATACAACTAGCACTTTCATTCCCC CCGTGTCTTTCCCTTAAAAAAACCTTACAAACTCGCCTCCTTTTACACAGACCACTACTA TTTGCACAACAGTAAGCCTACACAATTTATGTCTTGACACA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032852 |
| Insert Size | 1830 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_032852.2, NP_116241.2 |
| RefSeq Size | 1822 bp |
| RefSeq ORF | 1377 bp |
| Locus ID | 84938 |
| UniProt ID | Q96DT6 |
| Domains | Peptidase_C54 |
| Protein Families | Protease |
| Protein Pathways | Regulation of autophagy |
| Gene Summary | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) is the predominant transcript. Variants 1 and 2 encode the same protein. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MIR376A Is a Regulator of Starvation-Induced Autophagy
,null,
PLoS ONE
,PubMed ID 24358205
[ATG4C]
|
|
miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1.
,null,
Autophagy
,PubMed ID 22248718
[ATG4C]
|
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216088 | ATG4C (Myc-DDK-tagged)-Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1 |
CNY 3,656.00 |
|
| RC216088L1 | Lenti ORF clone of Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC216088L2 | Lenti ORF clone of Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC216088L3 | Lenti ORF clone of Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC216088L4 | Lenti ORF clone of Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG216088 | ATG4C (tGFP-tagged) - Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 1 |
CNY 4,370.00 |
