MICB (BC044218) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	MHC class I-like molecule PERB11.2-IMX; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I molecule; MHC class I polypeptide-r; OTTHUMP00000029089; OTTHUMP00000035091; OTTHUMP00000035588; PERB11.2; stress inducible class I homolog
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC044218 edited AGCGGTCGCTGAGCGGGGCGCAGGTGACTAAATTTCGACGGGGTCTTCTCACCGGTTTCA TTCAGTTGGCCACTGCTGAGCAGCTGAGAAGGTGGCGACGTAGGGGCCATGGGGCTGGGC CGGGTCCTGCTGTTTCTGGCCGTCGCCTTCCCTTTTGCACCCCCGGCAGCCGCCGCTGAG CCCCACAGTCTTCGTTACAACCTCATGGTGCTGTCCCAGGATGGATCTGTGCAGTCAGGG TTTCTCGCTGAGGGACATCTGGATGGTCAGCCCTTCCTGCGCTATGACAGGCAGAAACGC AGGGCAAAGCCCCAGGGACAGTGGGCAGAAGATGTCCTGGGAGCTGAGACCTGGGACACA GAGACCGAGGACTTGACAGAGAATGGGCAAGACCTCAGGAGGACCCTGACTCATATCAAG GACCAGAAAGGAGTGCCCCAGTCCTCCAGAGCTCAGACCTTGGCTATGAACGTCACAAAT TTCTGGAAGGAAGATGCCATGAAGACCAAGACACACTATCGCGCTATGCAGGCAGACTGC CTGCAGAAACTACAGCGATATCTGAAATCCGGGGTGGCCATCAGGAGAACAGTGCCCCCC ATGGTGAATGTCACCTGCAGCGAGGTCTCAGAGGGCAACATCACCGTGACATGCAGGGCT TCCAGCTTCTATCCCCGGAATATCACACTGACCTGGCGTCAGGATGGGGTATCTTTGAGC CACAACACCCAGCAGTGGGGGGATGTCCTGCCTGATGGGAATGGAACCTACCAGACCTGG GTGGCCACCAGGATTCGCCAAGGAGAGGAGCAGAGGTTCACCTGCTACATGGAACACAGC GGGAATCACGGCACTCACCCTGTGCCCTCTGGGAAGGCGCTGGTGCTTCAGAGTCAACGG ACAGACTTTCCATATGTTTCTGCTGCTATGCCATGTTTTGTTATTATTATTATTCTCTGT GTCCCTTGTTGCAAGAAGAAAACATCAGCGGCAGAGGGTCCAGAGCTTGTGAGCCTGCAG GTCCTGGATCAACACCCAGTTGGGACAGGAGACCACAGGGATGCAGCACAGCTGGGATTT CAGCCTCTGATGTCAGCTACTGGGTCCACTGGTTCCACTGAGGGCGCCTAGACTCTACAG CCAGGCGGCCAGGATTCAACTCCCTGCCTGGATCTCACCAGCACTTTCCCTCTGTTTCCT GACCTATGAAACAGAAAATAACATCACTTATTTATTGTTGTTGGATGCTGCAAAGTGTTA GTAGGTATGAGGTGTTTGCTGCTCTGCCACGTAGAGAGCCAGCAAAGGGATCATGACCAA CTCAACATTCCATTGGAGGCTATATGATCAAACAGCAAATTGTTTATCATGAATGCAGGA TGTGGGCAAACTCACGACTGCTCCTGCCAACAGAAGGTTTGCTGAGGGCATTCACTCCAT GGTGCTCATTGGAGTTATCTACTGGGTCATCTAGAGCCTATTGTTTGAGGAATGCAGTCT TACAAGCCTACTCTGGACCCAGCAGCTGACTCCTTCTTCCACCCCTCTTCTTGCTATCTC CTATACCAATAAATACGAAGGGCTGTGGAAGATCAGAGCCCTTGTTCACGAGAAGCAAGA AGCCCCCTGACCCCTTGTTCCAAATATACTCTTTTGTCTTTCTCTTTATTCCCACGTTCG CCCTTTGTTCAGTCCAATACAGGGTTGTGGGGCCCTTAACAGTGCCATATTAATTGGTAT CATTATTTCTGTTGTTTTTGTTTTTGTTTTTGTTTTTGTTTTTGAGACAGAGTCTCACTC TGTCACCCAGGCTGCAGTTCACTGGTGTGATCTCAGCTCACTGCAACCTCTGCCTCCCAG GTTCAAGCACTTCTCGTACCTCAGACTCCCGAATAGCTGGGATTACAGACAGGCACCACC ACACCCAGCTAATTTTTGTATTTTTTGTAGAGACGGGGTTTCGCCAAGTTGACCAGCCCA GTTTCAAACTCCTGACCTCAGGTGATCTGCCTGCCTTGGCATCCCAAAGTGCTGGGATTA CAAGAATGAGCCACCGTGCCTGGCCTATTTTATTATATTGTAATATATTTTATTATATTA GCCACCATGCCTGTCCTATTTTCTTATGTTTTAATATATTTTAATATATTACATGTGCAG TAATTAGATTATCATGGGTGAACTTTATGAGTGAGTATCTTGGTGATGACTCCTCCTGAC CAGCCCAGGACCAGCTTTCTTGTCACCTTGAGGTCCCCTCGCCCCGTCACACCGTTATGC ATTACTCTGTGTCTACTATTATGTGTGCATAATTTATACCGTAAATGTTTTCTCTTTAAA TTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites	NotI-NotI
ACCN	BC044218
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC044218.1, AAH44218.1
RefSeq Size	2390 bp
Locus ID	4277
Protein Families	Druggable Genome
Protein Pathways	Natural killer cell mediated cytotoxicity
Gene Summary	This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

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