TESC (BC015221) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	calcineurin B homologous protein 3; CHP3; FLJ20607; OTTHUMP00000185561; tescalcin; TSC
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC015221 edited CCGAGCCTTCGCCGGCGTCCCGACCCGAGGCCGGACCCGAGGCCAGTCCCGCCGCTGCGC AGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGCGGGCAC CATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTT CTCATCGGATCAGATCGAGCAGCTCCATCGGAGATTTAAGCAGCTGAGTGGAGATCAGCC TACCATTCGCAAGGAGAACTTCAACAATGTCCCGGACCTGGAGCTCAACCCCATCCGATC CAAAATTGTTCGTGCCTTCTTCGACAACAGGAACCTGCGCAAGGGACCCAGTGGCCTGGC TGATGAGATCAATTTCGAGGACTTCCTGACCATCATGTCCTACTTCCGGCCCATCGACAC CACCATGGACGAGGAACAGGTGGAGCTGTCCCGGAAGGAGAAGCTGAGATTTCTGTTCCA CATGTACGACTCGGACAGCGACGGCCGCATCACTCTGGAAGAATATCGAAATGTGGTCGA GGAGCTGCTGTCGGGAAACCCTCACATCGAGAAGGAGTCCGCTCGCTCCATCGCCGACGG GGCCATGATGGAGGCGGCCAGCGTGTGCATGGGGCAGATGGAGCCTGATCAGGTGTACGA GGGGATCACCTTCGAGGACTTCCTGAAGATCTGGCAGGGGATCGACATTGAGACCAAGAT GCACGTCCGCTTCCTTAACATGGAAACCATGGCCCTCTGCCACTGACCCACCGCCACCTC CGCGGAGAAACTGCACTTTGCAATGGGGCCGCCTCCCCGCGTAGCTGGAGCAGCCCAGGC CCGGCGGACAGCCTCTTCCTGCAGCGCCGGTACATAGCCAAGGCTCGTCTGCGCACCTTG TGTCTTGTAGGGTATGGTATGTGGGACTTCGCTGTTTTTATCTCCAATAAAAAAAAAAAA AAGGTTTGTTAAAAAAAAAAAAAAAAAAAA
Restriction Sites	NotI-NotI
ACCN	BC015221
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC015221.1, AAH15221.1
RefSeq Size	990 bp
Locus ID	54997
Gene Summary	Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.