MAX (BC003525) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; helix-loop-helix zipper protein; MAX protein; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; myc-associated factor X; MYC associated factor X; orf1
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC003525 edited GAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCT TCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAG CGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACT GGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCC ATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATAT CCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCA GAATGCTCTTCTGGAGCAGCAAGTCCGTGCACTGGAGAAGGCGAGGTCAAGTGCCCAACT GCAGACCAACTACCCCTCCTCAGACAACAGCCTCTACACCAACGCCAAGGGCAGCACCAT CTCTGCCTTCGATGGGGGCTCGGACTCCAGCTCGGAGTCTGAGCCTGAAGAGCCCCAAAG CAGGAAGAAGCTCCGGATGGAGGCCAGCTAAGCCACTCGGGGCAGGCCAGCAATAAAAAC TGTCTGTCTCCATCGTCTCATCCTCCTTTCAGTTCGTTGGTAGAGCCCTCAGAACCATTT AAGAGACTCTTTATTTTTCTCTTTCTCCCTTTTTTTTTTTAAATTTTTATTTTTACGTAG AAGCTCTTGGACAACAGCTCTCGTTCTCCTTCCCCATTTCCACTGTATATTTTTTAATGT ATTCCCTTCAGGGATTCCCTGTCCCCAACAGGAATTTTTAAACCAAAACACCCCAACTTG GCAGCTTTTTCTGTGGAGGACAGACGGCCGGCCGGACCTCTGAGCACATAGTGTCCTGCC CACCCTACCAGCTCCTCCAGCCCTGCCGGGCACATGCCCGGGGGACGCCTGCCCTGCCCA GGTGGCCTCCTGGCCCGCCCTCACCTCTGATAGACTTTGTGAATCTGAACTGCTCTACTT TGAGAAGATGACCGGTTTGGAGTAATCAGAATGAACCCTCCTCCTTTTTAAGGGTTTTTT TTTTTCCTTTTTCTAAAAAGCTATGTATCGCTCCTATTGAAAGACCAGATCCTTAGAGAA GTTTGTGGTATAAAAAGGAAGTGGGGACAGATTCGCAGCACAGAGTCGCTGGCATGTTTC ACTCCTGCTTCTCTCAGCCAGCTGTTTAAGCCTGCGGCGCCAGCCTCACGGAGGGCCGTG TGACACTCTCGTGGTATGTATGGGAGATGGCAGCAGTGAAGCAGCAGCCACCAGGGAGTG GCCATTTGGGGTTGGGACAGGGAGGGTGTTTTGGGTGGCATAGAGGTTTTGTATTGAGGG CCAGTGATGATGTTTTGATATTTATTTCCTGCTACTTAAATTTGAATCTGAGTGAATTGT ACCTATTTCTGATGATGTCGGTCTTGCAAAGCGACAGATTCATAAAGTAATGATGAAATC TTTCTTTCTTCCCGTGTGTATTTCTAAGAAATAGAGCCAACTGATTTTGTATGTAAATAC CAAGAGCAATTTACCTGGTACTAAACCCGCACCCCAGTGCGGACCCTTCCCAGCCCTCAT CCCACTTCCTTTCCTACTGTCCTGGAACCTGTCTCCATTGTGTGATCCAGCCCTGGTTCT GGCTGTGGTCAGCAGATGCCAGTGAAGGGTTTTGTGTGTTTAGGCCTCATTTCTTTGTCT TTTTCCTACTCCGTTCCTGGCATTTGCTGATTTCTAGTGTATACTCTGTAGTCTCAGTTC GTGTTTGATTCCATTCCATGGAAATAAAAAGTATGTTGTACATACTGCCGAAGAATTGTC TTGCAAGTTAAGGCTTCCCCCTACTATAAGACTATAAATAAAAACTTATTTTATCAAAAA AAAAAAAAAAAACCAAAAACCAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC003525 unedited GTTCGTATTTGTATACGACTCACTATAGGCGGCCGCGTAATTCGCACGAGGGAGTGAGTG TGTGTGTGGGGGGGACTCGGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTT CCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGA TGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAA ACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCA AGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATAT GCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCT TCTGGAGCAGCAAGTCCGTGCACTGGAGAAGGCGAGGTCAAGTGCCCAACTGCAGACCAA CTACCCCTCCTCAGACAACAGCCTCTACACCAACGCCAAGGGCAGCACCATCTCTGCCTT CGATGGGGGCTCGGACTCCAGCTCGGAGTCTGAGCCTGAAGAGCCCCAAAGCAGGAAGAA GCTCCGGATGGAGGCCAGCTAAGCCACTCGGGGCAGGCCAGCAATAAAAACTGTCTGTCT CCATCGTCTCATCCTCCTTTCAGTTCGTTGGTAGAGCCCTCAGAACCATTTAAGAAGACT CTTATTTTTCTCTTTCTCCCTTTTTTTTTTTAAATTTTTATTTTTACGTAGAAGCTCTTG GACACAGCTCTCGTTCTCCTTCCCATTTCCACTGTATATTTTTTAATGTATTCCCTTCAG GGATTCCTGGCCCCAACCGGAATTTTTAACCAAAACACCCCAACTGGCAGCTTTTTCTGT GGAAGACAAAGGCCGGCCGGCACTCTGACCACTAGTGTCCCG
Restriction Sites	NotI-NotI
ACCN	BC003525
Insert Size	2000 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC003525.1, AAH03525.1
RefSeq Size	1963 bp
Locus ID	4149
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	MAPK signaling pathway, Pathways in cancer, Small cell lung cancer
Gene Summary	The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.