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CAPNS1 (NM_001749) Human Untagged Clone
CAT＃: SC125531
CAPNS1 (untagged)-Human calpain, small subunit 1 (CAPNS1), transcript variant 1
CNY 3,600.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001749, the custom clone sequence may differ by one or more nucleotides
ATGTTCCTGGTTAACTCGTTCTTGAAGGGCGGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGG GCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGG CGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGC GAGGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACG AGAGTGAGGAGGTCCGGCAGTTCCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGC CACAGAACTCATGAACATTCTCAATAAGGTTGTGACACGACACCCTGATCTGAAGACTGATGGTTTTGGC ATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGGCTTTGAGGAAT TCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAGTTCGACACTGACCGATCAGG GACCATTTGCAGTAGTGAACTCCCAGGTGCCTTTGAGGCAGCAGGGTTCCACCTGAATGAGCATCTCTAT AACATGATCATCCGACGCTACTCAGATGAAAGTGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGG TCAGGCTGGACGCCATGTTCCGTGCCTTCAAATCTCTTGACAAAGATGGCACTGGACAAATCCAGGTGAA CATCCAGGAGTGGCTGCAGCTGACTATGTATTCCTGA >OriGene 5' read for NM_001749 unedited
CAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCAGAACT CCGGACGTGTGCGGCGCAGTGAGTCGCAGCCATGTTCCTGGTTAACTCGTTCTTGAAGGG CGGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGG AGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGG AGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAG CGAGGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTTCAACAT TGAGGCCAACGAGAGTGANGAAGTCCGGCAGTTCCGGAGACTCTTTGCCAGCTGGCTGGA GATGACTGAAGTCANCGCCACAGAACCATGAACATTCTCAATANGGGTGGACACGACAAC CTGATCTGAAGACTGATTGGTTTTGCATTGACACATGTCGCAACATGGTGGCCCGTGATT GATTACGACACCACAAGCCAGCTGTGCTTTGAAGAATCAAGTACTTGTGGAACCACCTCA AAGGTGGGCAGGCATTATCAAACAAGTCGAAACTGAACGATCAGGGACCATTTGCAGTAG TGAACTCCCCAGTGCTTTGAGCAGNCAGGTTTCACCTGATGAGCATCTTATACATGATCA TCCGACGCTCTCAAATGAAGTGGGACCATGGATNNTGACAACTCATCACTGCTTGTCAGG CTGACGCATGGGTCCGTGCTTCAATCTCTGACAAGATGGACTGACAAATCAGTGACTNCC AGGATGCTGAGTGACTTGATTCTGACCTGAGCCCAGACCGCCCCTACGCTGTTTAAAGAT ACTGGACCTNGCTTCAAGNCGACTTGGTGGCAATTTTTTGGGGGGCG >OriGene 3' read for NM_001749 unedited
AGCTATGGACCGCGCGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGGAGATAG CAACTGGGGCATGTTTATTTCCTCCTGGGCCTGGCAGGCTGGGAGCAGAATATAGACAAA GGCACTGGGGCACCTGGGTCTGGCACGGTCTGGAGCTTGGCCGCCTGGGTAGCAACCGTG AAGGGTGTGCCAGGGCGTGCAGGGACTGGAGTCATCCTCCCAGAACTGAGAGAGGGCCCT CGGGGCATGGAGGCATCACAAGTGCTAGGCTTGGCACAGGTACAGGGGAGAGGTTACGGA GTGGGTGTGTGCAGGGCCTGGTGGGAATGGGGAGACCCGTGGACAGAGCTTGTTAGAGTG TCCTAGAGCCAGGGGGAACTCCAGGCAGGGCAAATTGGGCCCTGGATGTTGAGAAGCTGG GTAACAAGTACTGAGAGAACAAAAGCTTGTGGGTCAGCAGGCCCCACAAAGATGTGACTG CAGACAGGATCGGCCCTGGGAGAGACCGAGGCTCCAGGTGACTCCTATAGCAAGGCGGTG AGGGGGCGGGTCTGGGGCTCCAGTTCAGGAATACATAGTCAGCTGCAGCCACTCCTGGAT GTTCACCTGGATTTGTCCAGTGCCATCTTTGTCAAGAGATTTGAAGGCACGGAACATGGC GTCCAGCCTGACCAAGCAGCTGATGAAGTTGTCAAAATCCATGTTCCCACTTTCATCTGA GTAGCGTCGGATGATCATGTTATAGAGATGCTCATTTAGGTGGTACCCTGCTGCCTCAAA GGCACCTGGGAGNTCACTACTGCAAATGGTCCCTGATCGGTCAGTGCCGAACTGTTTTGA TATGGCCTGCCACCCTTTGATGGTGTTCCACAAGTACTTGAATTTCCTCAAGCCCAGCTT GCCTGGGNTGTCGCTATCCATCACCGGCACATGCTGGGAATGNGTCATGCCACAACATCA CT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001749 |
| Insert Size | 1430 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001749.2, NP_001740.1 |
| RefSeq Size | 1492 bp |
| RefSeq ORF | 807 bp |
| Locus ID | 826 |
| UniProt ID | P04632 |
| Domains | EFh |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1, 2 and 3 encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212322 | CAPNS1 (Myc-DDK-tagged)-Human calpain, small subunit 1 (CAPNS1), transcript variant 1 |
CNY 3,840.00 |
|
| RC212322L3 | Lenti-ORF clone of CAPNS1 (Myc-DDK-tagged)-Human calpain, small subunit 1 (CAPNS1), transcript variant 1 |
CNY 5,890.00 |
|
| RC212322L4 | Lenti-ORF clone of CAPNS1 (mGFP-tagged)-Human calpain, small subunit 1 (CAPNS1), transcript variant 1 |
CNY 5,890.00 |
|
| RG212322 | CAPNS1 (tGFP-tagged) - Human calpain, small subunit 1 (CAPNS1), transcript variant 1 |
CNY 4,370.00 |
