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EPOR (NM_000121) Human Untagged Clone
CAT＃: SC125440
EPOR (untagged)-Human erythropoietin receptor (EPOR), transcript variant 1
CNY 5,688.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EPO-R |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125440 sequence for NM_000121 edited (data generated by NextGen Sequencing)
ATGGACCACCTCGGGGCGTCCCTCTGGCCCCAGGTCGGCTCCCTTTGTCTCCTGCTCGCT GGGGCCGCCTGGGCGCCCCCGCCTAACCTCCCGGACCCCAAGTTCGAGAGCAAAGCGGCC TTGCTGGCGGCCCGGGGGCCCGAAGAGCTTCTGTGCTTCACCGAGCGGTTGGAGGACTTG GTGTGTTTCTGGGAGGAAGCGGCGAGCGCTGGGGTGGGCCCGGGCAACTACAGCTTCTCC TACCAGCTCGAGGATGAGCCATGGAAGCTGTGTCGCCTGCACCAGGCTCCCACGGCTCGT GGTGCGGTGCGCTTCTGGTGTTCGCTGCCTACAGCCGACACGTCGAGCTTCGTGCCCCTA GAGTTGCGCGTCACAGCAGCCTCCGGCGCTCCGCGATATCACCGTGTCATCCACATCAAT GAAGTAGTGCTCCTAGACGCCCCCGTGGGGCTGGTGGCGCGGTTGGCTGACGAGAGCGGC CACGTAGTGTTGCGCTGGCTCCCGCCGCCTGAGACACCCATGACGTCTCACATCCGCTAC GAGGTGGACGTCTCGGCCGGCAACGGCGCAGGGAGCGTACAGAGGGTGGAGATCCTGGAG GGCCGCACCGAGTGTGTGCTGAGCAACCTGCGGGGCCGGACGCGCTACACCTTCGCCGTC CGCGCGCGTATGGCTGAGCCGAGCTTCGGCGGCTTCTGGAGCGCCTGGTCGGAGCCTGTG TCGCTGCTGACGCCTAGCGACCTGGACCCCCTCATCCTGACGCTCTCCCTCATCCTCGTG GTCATCCTGGTGCTGCTGACCGTGCTCGCGCTGCTCTCCCACCGCCGGGCTCTGAAGCAG AAGATCTGGCCTGGCATCCCGAGCCCAGAGAGCGAGTTTGAAGGCCTCTTCACCACCCAC AAGGGTAACTTCCAGCTGTGGCTGTACCAGAATGATGGCTGCCTGTGGTGGAGCCCCTGC ACCCCCTTCACGGAGGACCCACCTGCTTCCCTGGAAGTCCTCTCAGAGCGCTGCTGGGGG ACGATGCAGGCAGTGGAGCCGGGGACAGATGATGAGGGCCCCCTGCTGGAGCCAGTGGGC AGTGAGCATGCCCAGGATACCTATCTGGTGCTGGACAAATGGTTGCTGCCCCGGAACCCG CCCAGTGAGGACCTCCCAGGGCCTGGTGGCAGTGTGGACATAGTGGCCATGGATGAAGGC TCAGAAGCATCCTCCTGCTCATCTGCTTTGGCCTCGAAGCCCAGCCCAGAGGGAGCCTCT GCTGCCAGCTTTGAGTACACTATCCTGGACCCCAGCTCCCAGCTCTTGCGTCCATGGACA CTGTGCCCTGAGCTGCCCCCTACCCCACCCCACCTAAAGTACCTGTACCTTGTGGTATCT GACTCTGGCATCTCAACTGACTACAGCTCAGGGGACTCCCAGGGAGCCCAAGGGGGCTTA TCCGATGGCCCCTACTCCAACCCTTATGAGAACAGCCTTATCCCAGCCGCTGAGCCTCTG CCCCCCAGCTATGTGGCTTGCTCTTAG Clone variation with respect to NM_000121.3 >OriGene 5' read for NM_000121 unedited
GACTCACTATAGGGCGGCCGCGAATTCGGCACCANCCANGCAGCTGCTGACCCAGCTGTG GACTGTGCCGGGGGCGGGGGACAGAGGGGCACGAGCCCTGGGCTCCCCGTGGCGGGGGCT GTATCATGGACCACCTCGGGGCGTCCCTCTGGCCCCAGGTCGGCTCCCTTTGCTCCTGGT GCTGGGGCCGCCTGGGCGCCCCCGCCTAACCTTCCGGACCCCAAGTTCGAGAGCAAAGCG GCCTTGCTGGCGGCCCGGGGGCCCGAAGAGCTTCTGGGCTTCACCGAGCGGTTGGAGGAC TTGGTGTGTTTCTGGGAGGAAGCGGCGAGCGCTGGGGTGGGCCCGGGCAACTACAGCTTC TCCTACCAGCTCGAGGATGAGCCATGGGAGCTGTGTCGCCTGCACCAGGCTCCCACGGCT CGTGGTGCGGTGCGCTTCTGGTGGTCGCTGCCTACAGCCGACACGTTGAGGCTTGGTGCC CCTAGAGGTGCGCGGTAAAAGAAGGCTTCGGGCGGCTTCGGGAATATTAACCGGGGTCAT TCCACTATAAATGGAAGGTAGGGCTTCCTAAGAACGCCCCCCGTGGGGGGCTGGGTTGGG CCCGGTTTTGGCTTGAACCAAAGAAGCGGGCACAACGGTAAGTGGTTTTGGCGCTTGGGT TTTCCCCGGCCCGGCCTGGAAGAACCACCCCCATGGGACGGTTTTTTAAAATATTTCGGT TTTACGAAGGGGTGAAACGGTTTTTGGGGCCCGGGCAAAACGGGGGCCACAGGGGAGCGC GTACACAAAAAGGGGGGGGAAAATACCCCCTGGAGAGGGGCCCCCCCCCCCGGGATGGGG TGGGCCTGGAGAAAACACTCCGTGGGC >OriGene 3' read for NM_000121 unedited
TAGGGCCAGGAGAGGCACTGGGGAGGGGTNANANGGATGCCACCCGGGATCTGTTCAGGA AACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTATGTG GATATATATATATAGATACCAAAAAAAACTATTCATATTTAAAAATACTGCAAGGGTGTG GTTTCCTGAACAAGATGGATTGGGCAAACCAAATCAACAATTGCCCTTGTTCTGAAAAAG GGCTTCGCATTCCTGGTTCATAAGTCTTGAGTCTGCACTGGTTCTCTGAGTCATATTGGA TCCCTGATCATCTGCAGCCTGGTGTCCTAAGAGCAAGCCACATAGCTGGGGGGCAGAGGC TCAGCGGCTGGGATAGGCTGTTCTCATANGGGTGGAGTANGGGCCATCNGATAAGCCCCC TTGGGCTCCNTGGGAGTCCCCTGAGCTGTAGTCAGTTGAGATGCCAGAGTCAGATACCCA CAGGTACAGGTACTTTNAAGTGGGTTGGGGTAAGGGGCAACTCAGGGGCACAGTGTCCAT GGACGCANGAGCTGGNAGCTGGNGTCAAGATAGTGACTCAAGCTGGCACAGAGCTCCTCT GGCTGGCTTTCAGCCAACAATGACAGAGATCTCTGACTTATCATGGCATATTCACATGCA CAGCCCTGAGTCTACTGCGGTTCGGCACACATTGCAGACAATAGTC |
| Restriction Sites | Please inquire |
| ACCN | NM_000121 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000121.2, NP_000112.1 |
| RefSeq Size | 1849 bp |
| RefSeq ORF | 1527 bp |
| Locus ID | 2057 |
| UniProt ID | P19235 |
| Domains | FN3 |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway |
| Gene Summary | This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Engineering of erythropoietin receptor for use as an affinity ligand
,Hatayama, K;Ide, T;,
Protein Expr. Purif.
,PubMed ID 25795089
[EPOR]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211341 | EPOR (Myc-DDK-tagged)-Human erythropoietin receptor (EPOR), transcript variant 1 |
CNY 5,672.00 |
|
| RC211341L1 | Lenti-ORF clone of EPOR (Myc-DDK-tagged)-Human erythropoietin receptor (EPOR), transcript variant 1 |
CNY 8,072.00 |
|
| RC211341L2 | Lenti-ORF clone of EPOR (mGFP-tagged)-Human erythropoietin receptor (EPOR), transcript variant 1 |
CNY 8,072.00 |
|
| RC211341L3 | Lenti-ORF clone of EPOR (Myc-DDK-tagged)-Human erythropoietin receptor (EPOR), transcript variant 1 |
CNY 8,072.00 |
|
| RC211341L4 | Lenti-ORF clone of EPOR (mGFP-tagged)-Human erythropoietin receptor (EPOR), transcript variant 1 |
CNY 8,072.00 |
|
| RG211341 | EPOR (tGFP-tagged) - Human erythropoietin receptor (EPOR), transcript variant 1 |
CNY 7,272.00 |
