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Tapasin (TAPBP) (NM_172209) Human Untagged Clone
CAT＃: SC125028
TAPBP (untagged)-Human TAP binding protein (tapasin) (TAPBP), transcript variant 3
CNY 3,656.00
CNY 5,800.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NGS17; TAPA; TPN; TPSN |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125028 sequence for NM_172209 edited (data generated by NextGen Sequencing)
ATGAAGTCCCTGTCTCTGCTCCTCGCTGTGGCTTTGGGCCTGGCGACCGCCGTCTCAGCA GGACCCGCGGTGATCGAGTGTTGGTTCGTGGAGGATGCGAGCGGAAAGGGCCTGGCCAAG AGACCCGGTGCACTGCTGTTGCGCCAGGGACCCGGGGAACCGCCGCCCCGGCCGGACCTC GACCCTGAGCTCTATCTCAGTGTACACGTGGTACTGACTGTCCTCACCCACACCCCTGCC CCTCGAGTGAGACTGGGACAAGATGCTCTGCTGGACTTGAGCTTTGCCTACATGCCCCCC ACCTCCGAGGCCGCCTCATCTCTGGCTCCGGGTCCCCCTCCCTTTGGGCTAGAGTGGCGA CGCCAGCACCTGGGTAAGGGACATCTGCTCCTGGCTGCAACTCCTGGGCTGAATGGCCAG ATGCCAGCAGCCCAAGAAGGGGCCGTGGCATTTGCTGCTTGGGATGATGATGAGCCATGG GGCCCATGGACCGGAAATGGGACCTTCTGGCTGCCTAGAGTTCAACCCTTTCAGGAGGGC ACCTATCTGGCCACCATACACCTGCCATACCTGCAAGGACAGGTCACCCTGGAGCTTGCT GTGTACAAACCCCCCAAAGTGTCCCTGATGCCAGCAACCCTTGCACGGGCCGCCCCAGGG GAGGCACCCCCGGAATTGCTCTGCCTTGTGTCCCACTTCTACCCTTCTGGGGGCCTGGAG GTGGAGTGGGAACTCCGGGGTGGCCCAGGGGGCCGCTCTCAGAAGGCCGAGGGGCAGAGG TGGCTCTCGGCCCTGCGCCACCATTCCGATGGCTCTGTCAGCCTCTCTGGGCACTTGCAG CCGCCCCCAGTCACCACTGAGCAGCATGGGGCACGCTATGCCTGTCGAATTCACCATCCC AGCCTGCCTGCCTCGGGGCGCAGCGCTGAGGTCACCCTGGAGGTAGCAGGTCTTTCAGGG CCCTCCCTTGAGGACAGCGTAGGCCTTTTCCTGTCTGCCTTTCTTCTGCTTGGGCTCTTC AAGGCACTGGGCTGGGCTGCTGTCTACCTGTCCACCTGCAAGGATTCAAAGAAGAAAGCA GAGTGA Clone variation with respect to NM_172209.2 153 g=>c;518 c=>g >OriGene 5' read for NM_172209 unedited
ATATCCCCGCCCGTTGACGCAATGGGCGGTAGGCGTGTACCGGTGGGCAGGTCTATATAA GCAGAGCTCATTTAGGTGACACTATAGAATACACGCTACTTGTTCTTTTTGCAGCGGCCG CGAATTCGGCACGAGGGGAGGTCGCAGCGCCATGAAGTCCCTGTCTCTGCTCCTCGCTGT GGCTTTGGGCCTGGCGACCGCCGTCTCAGCAGGACCCGCGGTGATCGAGTGTTGGTTCGT GGAGGATGCGAGCGGAAAGGGCCTGGCCAAGAGACCCGGTGCACTGCTGTTGCGCCAGGG ACCCGGGGAACCGCCGCCCCGGCCGGACCTCGACCCTGAGCTCTATCTCAGTGTACACGA CCCCGCGGGCGCCCTCCAGGCTGCCTTCAGGCGGTATCCCCGGGGCGCCCCCGCACCACA CTGCGAGATGAGCCGCTTCGTGCCTCTCCCCGCCTCTGCGAAATGGGCCAGCGGCCTGAC CCCCGCGCAGAACTGCCCGCGGGCCCTGGATGGGGCTTGGCTGATGGTCAGCATATCCAG CCCAGTCCTCAGCCTCTCCAGCCTCTTGCGACCACAGCCAGAGCCTCAGCAGGAGCCTGT TCTCATCACCATGGCAACAGTGGTACTGACTGTCCTCACCCACACCCCTGCCCCTCGAGT GAGACTGGGACAAGATGCTCTGCTGGACTTGAGCTTTGCCTACATGCCCCCCACCTCCGA GGCCGCCTCATCTCTGGCTACGGGTCCCCCTCCCTTTTGGCTAGAGTGGCGACGCCAGCA CCTGNGGTAGGGGACATCTGCTCCTGGCTGCAACTCCTGGGCTGAATGGCCAGATGCCAG CAGCCCAAGAGGGGCCCGTGGCATATGCTGCTTGGGATGATGATGAGCCATGGGCCCCAT GACCTGAACGGGCACCTTCTGCTGCCTAGAGTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_172209 |
| Insert Size | 3900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_172209.1, NP_757346.1 |
| RefSeq Size | 1410 bp |
| RefSeq ORF | 1239 bp |
| Locus ID | 6892 |
| UniProt ID | O15533 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Antigen processing and presentation |
| Gene Summary | This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222140 | TAPBP (Myc-DDK-tagged)-Human TAP binding protein (tapasin) (TAPBP), transcript variant 3 |
CNY 1,200.00 |
|
| RC222140L3 | Lenti-ORF clone of TAPBP (Myc-DDK-tagged)-Human TAP binding protein (tapasin) (TAPBP), transcript variant 3 |
CNY 5,890.00 |
|
| RC222140L4 | Lenti-ORF clone of TAPBP (mGFP-tagged)-Human TAP binding protein (tapasin) (TAPBP), transcript variant 3 |
CNY 5,890.00 |
|
| RG222140 | TAPBP (tGFP-tagged) - Human TAP binding protein (tapasin) (TAPBP), transcript variant 3 |
CNY 4,370.00 |
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