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Dopamine Receptor D3 (DRD3) (NM_000796) Human Untagged Clone
CAT＃: SC124083
DRD3 (untagged)-Human dopamine receptor D3 (DRD3), transcript variant a
CNY 3,656.00
CNY 7,220.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | D3DR; ETM1; FET1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000796, the custom clone sequence may differ by one or more nucleotides
ATGGCATCTCTGAGCCAGCTGAGTGGCCACCTGAACTACACCTGTGGGGCAGAGAACTCCACAGGTGCCA GCCAGGCCCGCCCACATGCCTACTATGCCCTCTCCTACTGCGCGCTCATCCTGGCCATCGTCTTCGGCAA TGGCCTGGTGTGCATGGCTGTGCTGAAGGAGCGGGCCCTGCAGACTACCACCAACTACTTAGTAGTGAGC CTGGCTGTGGCAGACTTGCTGGTGGCCACCTTGGTGATGCCCTGGGTGGTATACCTGGAGGTGACAGGTG GAGTCTGGAATTTCAGCCGCATTTGCTGTGATGTTTTTGTCACCCTGGATGTCATGATGTGTACAGCCAG CATCCTTAATCTCTGTGCCATCAGCATAGACAGGTACACTGCAGTGGTCATGCCCGTTCACTACCAGCAT GGCACGGGACAGAGCTCCTGTCGGCGCGTGGCCCTCATGATCACGGCCGTCTGGGTACTGGCCTTTGCTG TGTCCTGCCCTCTTCTGTTTGGCTTTAATACCACAGGGGACCCCACTGTCTGCTCCATCTCCAACCCTGA TTTTGTCATCTACTCTTCAGTGGTGTCCTTCTACCTGCCCTTTGGAGTGACTGTCCTTGTCTATGCCAGA ATCTATGTGGTGCTGAAACAAAGGAGACGGAAAAGGATCCTCACTCGACAGAACAGTCAGTGCAACAGTG TCAGGCCTGGCTTCCCCCAACAAACCCTCTCTCCTGACCCGGCACATCTGGAGCTGAAGCGTTACTACAG CATCTGCCAGGACACTGCCTTGGGTGGACCAGGCTTCCAAGAAAGAGGAGGAGAGTTGAAAAGAGAGGAG AAGACTCGGAATTCCCTGAGTCCCACCATAGCGCCCAAGCTCAGCTTAGAAGTTCGAAAACTCAGCAATG GCAGATTATCGACATCTTTGAAGCTGGGGCCCCTGCAACCTCGGGGAGTGCCACTTCGGGAGAAGAAGGC AACCCAAATGGTGGCCATTGTGCTTGGGGCCTTCATTGTCTGCTGGCTGCCCTTCTTCTTGACCCATGTT CTCAATACCCACTGCCAGACATGCCACGTGTCCCCAGAGCTTTACAGTGCCACGACATGGCTGGGCTACG TGAATAGCGCCCTCAACCCTGTGATCTATACCACCTTCAATATCGAGTTCCGGAAAGCCTTCCTCAAGAT CCTGTCTTGCTGA >OriGene 5' read for NM_000796 unedited
ATACGACTCACTATAGGGCGGCCGCCAGTGTGATGGATATCTGCAGAATTCGGCTTATGG CATCTCTGAGTCAGCTGAGTAGCCACCTGAACTACACCTGTGGGGCAGAGAACTCCACAG GTGCCAGCCAGGCCCGCCCACATGCCTACTATGCCCTCTCCTACTGCGCGCTCATCCTGG CCATCGTCTTCGGCAATGGCCTGGTGTGCATGGCTGTGCTGAAGGAGCGGGCCCTGCAGA CTACCACCAACTACTTAGTAGTGAGCCTGGCTGTGGCAGACTTGCTGGTGGCCACCTTGG TGATGCCCTGGGTGGTATACCTGGAGGTGACAGGTGGAGTCTGGAATTTCAGCCGCATTT GCTGTGATGTTTTTGTCACCCTGGATGTCATGATGTGTACAGCCAGCATCCTTAATCTCT GTGCCATCAGCATAGACAGGTACACTGCAGTGGTCATGCCCGTTCACTACCAGCATGGCA CGGGACAGAGCTCCTGTCGGCGCGTGGCCCTCATGATCACGGCCGTCTGGGTACTGGCCT TTGCTGTGTCCTGCCCTCTTCTGTTTGGCTTTAATACCACAGGGGACCCCACTGTCTGCT CCATCTCCAACCCTGATTTTGTCATCTACTCTTCAGTGGTGTCCTTCTACCTGCCCTTTG GAGTGACTGTCCTTGTCTATGCCAGAATCTATGTGGTGCTGAAACAAAGGAGACGGANAA GGATCCTCACTCGACAGAA >OriGene 3' read for NM_000796 unedited
NAGGCACTGGGCCAGGGGTCACAGGGATGCCACCTTGGATCTGTTCAGGAAACAGCTATG ACCGCGGCCGCAATCTAGAGTCGACAAGCTTGATATCGGTACCGAGCTCGGATCCACTAG TAACGGCCGCCAGTGTGCTGGAATTCGGCTTTCAGCAAGACAGGATCTTGAGGAAGGCTT TCCGGAACTCGATATTGAAGGTGGTATAGATCACAGGGTTGAGGGCGCTATTCACGTAGC CCAGCCATGTCGTGGCACTGTAAAGCTCTGGGGACACGTGGCATGTCTGGCAGTGGGTAT TGAGAACATGGGTCAAGAAGAAGGGCAGCCAGCAGACAATGAAGGCCCCAAGCACAATGG CCACCATTTGGGTTGCCTTCTTCTCCCGAAGTGGCACTCCCCGAGGTTGCAGGGGCCCCA GCTTCAAAGATGTCGATAATCTGCCATTGCTGAGTTTTCGAACTTCTAAGCTGAGCTTGG GCGCTATGGTGGGACTCAGGGAATTCCGAGTCTTCTCCTCTCTTTTCAACTCTCCTCCTC TTTCTTGGAAGCCTGGTCCACCCAAGGCAGTGTCCTGGCAGATGCTGTAGTAACGCTTCA GCTCCAGATGTGCCGGGTCAGGAGAGAGGGTTTGTTGGGGGAAGCCAGGCCTGACACTGG TGCACCTGACTGGTTTGTCCAGTGAGGATCCCTTTTCCGGCTTCCTTGGGTTCAGCACCA CATATATTTTTGGCGTAGACCAAGACAGGCTCTCCCAAAGGCCGGTTGGAAGGCACCCCT CTAGAGGATAGCACCCAAATTCGGGTTTGGGAAATAGGATACATAGGGGCGCCCTCTGTG GTTTTAAAGCCAACAAAAAAGGCGGGGACCCGCTAGAGGCTGCCCACAACGGGCGTGTTC TAGGGGGCCACCCGCCG |
| Restriction Sites | Please inquire |
| ACCN | NM_000796 |
| Insert Size | 1300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000796.2, NP_000787.1 |
| RefSeq Size | 1496 bp |
| RefSeq ORF | 1203 bp |
| Locus ID | 1814 |
| UniProt ID | P35462 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008] Transcript Variant: This variant (a) represents the predominant transcript and encodes the longer isoform (a). Variants a, f and g encode the same isoform (a). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists
,Micheli, F;Bacchi, A;Braggio, S;Castelletti, L;Cavallini, P;Cavanni, P;Cremonesi, S;Dal Cin, M;Feriani, A;Gehanne, S;Kajbaf, M;Marchió, L;Nola, S;Oliosi, B;Pellacani, A;Perdona', E;Sava, A;Semeraro, T;Tarsi, L;Tomelleri, S;Wong, A;Visentini, F;Zonzini, L;Heidbreder, CA;,
J. Med. Chem.
,PubMed ID 27564135
[DRD3]
|
|
1,2,4-Triazolyl octahydropyrrolo[2,3-b]pyrroles: A new series of potent and selective dopamine D3 receptor antagonists
,Micheli, F;Bernardelli, A;Bianchi, F;Braggio, S;Castelletti, L;Cavallini, P;Cavanni, P;Cremonesi, S;Cin, MD;Feriani, A;Oliosi, B;Semeraro, T;Tarsi, L;Tomelleri, S;Wong, A;Visentini, F;Zonzini, L;Heidbreder, C;,
Bioorg. Med. Chem.
,PubMed ID 26951894
[DRD3]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223426 | DRD3 (Myc-DDK-tagged)-Human dopamine receptor D3 (DRD3), transcript variant a |
CNY 3,656.00 |
|
| RC223426L1 | Lenti ORF clone of Human dopamine receptor D3 (DRD3), transcript variant a, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223426L2 | Lenti ORF clone of Human dopamine receptor D3 (DRD3), transcript variant a, mGFP tagged |
CNY 5,890.00 |
|
| RC223426L3 | Lenti ORF clone of Human dopamine receptor D3 (DRD3), transcript variant a, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223426L4 | Lenti ORF clone of Human dopamine receptor D3 (DRD3), transcript variant a, mGFP tagged |
CNY 5,890.00 |
|
| RG223426 | DRD3 (tGFP-tagged) - Human dopamine receptor D3 (DRD3), transcript variant a |
CNY 4,370.00 |
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