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KIR2.3 (KCNJ4) (NM_152868) Human Untagged Clone
CAT＃: SC123919
KCNJ4 (untagged)-Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1
CNY 3,656.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HIR; HIRK2; HRK1; IRK-3; IRK3; Kir2.3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC123919 sequence for NM_152868 edited (data generated by NextGen Sequencing)
ATGCACGGACACAGCCGCAACGGCCAGGCCCACGTGCCCCGGCGGAAGCGCCGCAACCGC TTCGTCAAGAAGAACGGCCAATGCAACGTGTACTTCGCCAACCTGAGCAACAAGTCGCAG CGCTACATGGCGGACATCTTCACCACCTGCGTGGACACGCGCTGGCGCTACATGCTCATG ATCTTCTCCGCGGCCTTCCTTGTCTCCTGGCTCTTTTTCGGCCTCCTCTTCTGGTGTATC GCCTTCTTCCACGGTGACCTGGAGGCCAGCCCAGGGGTGCCTGCGGCGGGGGGCCCGGCG GCGGGTGGTGGCGGAGCAGCCCCGGTGGCCCCCAAGCCCTGCATCATGCACGTGAACGGC TTCCTGGGTGCCTTCCTGTTCTCGGTGGAGACGCAGACGACCATCGGCTATGGGTTCCGG TGCGTGACAGAGGAGTGCCCGCTGGCAGTCATCGCTGTGGTGGTCCAGTCCATCGTGGGC TGCGTCATCGACTCCTTCATGATTGGCACCATCATGGCCAAGATGGCGCGGCCCAAGAAG CGGGCGCAGACGTTGCTGTTCAGCCACCACGCGGTCATTTCGGTGCGCGACGGCAAGCTC TGCCTCATGTGGCGCGTGGGCAACCTGCGCAAGAGCCACATTGTGGAGGCCCACGTGCGG GCCCAGCTCATCAAGCCCTACATGACCCAGGAGGGCGAGTACCTGCCCCTGGACCAGCGG GACCTCAACGTGGGCTATGACATCGGCCTGGACCGCATCTTCCTGGTGTCGCCCATCATC ATTGTCCACGAGATCGACGAGGACAGCCCGCTTTATGGCATGGGCAAGGAGGAGCTGGAG TCGGAGGACTTTGAGATCGTGGTCATCCTGGAGGGCATGGTGGAGGCCACGGCCATGACC ACCCAGGCCCGCAGCTCCTACCTGGCCAGCGAGATCCTGTGGGGCCACCGCTTTGAGCCT GTGGTCTTCGAGGAGAAGAGCCACTACAAGGTGGACTACTCGCGTTTTCACAAGACCTAC GAGGTGGCCGGCACGCCCTGCTGCTCGGCCCGGGAGCTGCAGGAGAGTAAGATCACCGTG CTGCCCGCCCCACCGCCCCCTCCCAGTGCCTTCTGCTACGAGAACGAGCTGGCCCTTATG AGCCAGGAGGAAGAGGAGATGGAGGAGGAGGCAGCTGCGGCGGCCGCGGTGGCCGCAGGC CTGGGCCTGGAGGCGGGTTCCAAGGAGGAGGCGGGCATCATCCGGATGCTGGAGTTCGGC AGCCACCTGGACCTGGAGCGCATGCAGGCTTCCCTCCCGCTGGACAACATCTCCTACCGC AGGGAGTCTGCCATCTGA Clone variation with respect to NM_152868.1 1002 a=>g >OriGene 5' read for NM_152868 unedited
CCACTGCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGGAGCGGCGCGGGACGGCCGG GACGCGCGGAGACCCCAAGACCCACGCGCAGACCGAGCGGCAGCCGGGGAGGGGAGCGCG GGCCGGCCGGCCGAGTTCGCGGGCAGGGGGCGCCGGGACTCCCCTCTCCGCGCCCGGGAC GCCGCCCGCCGGATCGCGCCTTGGGATGTAGCGCCCGCTCGGCGCCTCCCGGACTCTCGT CGGACCCTCCGCCCAGCGGCCCTGCGTCTTCCCAGGTGACCACGCCGGCTTCAGGACATG CACGGACACAGCCGCAACGGCCAGGCCCACGTGCCCCGGCGGAAGCGCCGCAGCCGCTTC GTCAAGAAGAACGGCCAATGCAACGTGTACTTCGCCAACCTGAGCAACAAGTCGCAGCGC TACATGGCGGACATCTTCACCACCTGCGTGGACACGCGCTGGCGCTACATGCTCATGATC TTCTCCGCGGCCTTCCTTGTCTCCTGGCTCTTTTTCGGCCTCCTCTTCTGGTGTATCGCC TTCTTCCACGGTGACCTGAAGGCCATCCCACGGGTGCCTGCGGCGGTGGGCCCGGCAGCG GGTGGTGGCGGATCAGCCCCGGTGGCCCCCAAGCCCTGCATCATGCACGTGAACGGCTTC CTGGGTGCCTTCCTGTTCTCGGTGGAGACGCACACGACCATCGGCTATGGGTTCCGGTGC GTGACAGACGAGTGCCCGCTGGCAGTCATCGCTGTGGN >OriGene 3' read for NM_152868 unedited
TCCAGGCCAGGATAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGG AAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTGTTTTTTTTTTTTTTT TTTTTTTGGGGGCTCCATCTGTCTCCATTTATAGATATTTACAAAAGAAAGTCATGAGCA ACAGGCCACAGTCATGCAAAAGAAACGCACCCCCCCTCCCCAAACTAACCCCCTGCCCAC CCTGAAACCCCGAGATGTCCCCCGCCCAGCAGTCCAGCCACCTTCCCCAAGGTTCTGAGA GCAAAGAGGGCACGTCCTTGAAGAGTCAGTGGGGGAAGGGTGGTGGATCCGGGGACCTAG AGCCACCAGAAGTAGGCGCTGGCGGAACTCAGGCTGATCGGGGCCGAGCTCTTCCCAGGC CTGGGTGCTGGAGTCAGGAGGAAGGGGTCCCCCAGTCTTTGAAACCCCCACCTTCCTCCA GAAGGTCCACGGAGCCAGGGTTGGCTCTGTCCTGAGTGTGGGAGGGGGTGTCCTGGCATC CCACCCCCGGCAGAGGCTCTTGTGGGCAGTGGTGAGGGCCGGGCCTGGAGGTCAGATGGC AGACTCCCTGCGGTAGGAGATGTTGTCCAGCGGGAGGGAAGCCTGCGTGCGCTCCAGGTC CAGGTGGCTGCCGAACTTCAGCATCCGGGTGATGCCCGCCTCCTCCTTTGGACCCGGCTT CAGGCCCAGGCCTGGGGCCACCGCGGCCGCCGCAGCTGCC |
| Restriction Sites | Please inquire |
| ACCN | NM_152868 |
| Insert Size | 4600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152868.1, NP_690607.1 |
| RefSeq Size | 2063 bp |
| RefSeq ORF | 1338 bp |
| Locus ID | 3761 |
| UniProt ID | P48050 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Development of a Selective Small-Molecule Inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel
,Gautam Bhave, Brian A. Chauder, Wen Liu, Eric S. Dawson, Rishin Kadakia, Thuy T. Nguyen, L. Michelle Lewis, Jens Meiler, C. David Weaver, Lisa M. Satlin, Craig W. Lindsley, and Jerod S. Denton,
Mol. Pharmacol., Jan 2011; 79: 42 - 50
[KCNJ4]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223261 | KCNJ4 (Myc-DDK-tagged)-Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1 |
CNY 3,656.00 |
|
| RC223261L1 | Lenti ORF clone of Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223261L2 | Lenti ORF clone of Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC223261L3 | Lenti ORF clone of Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223261L4 | Lenti ORF clone of Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG223261 | KCNJ4 (tGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1 |
CNY 4,370.00 |
