NRP2 (BC009222) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	MGC126574; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); neuropilin 2; NP2; NPN2; PRO2714; receptor for VEGF165 and semaphorins class3; vascular endothelial growth factor-165 receptor 2; VEGF165R2
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC009222 edited GGCACGAGGGCAGAGCATGTTTGGGACATAACAAAGGATCTGAGTAGTAAACACCGTACG CCACCCAACTCCTCTTGTAACGCCATCGCGCGTGGCATTGTGTTGGGTTCTGCGTGTGTG GCATCGGAGTCGTGGAATTTAGGGGGAACAAGGCTTTTCCCCCCGTCCCCCCGGGGTCTC CCTTGGGTGGGGGCGACACGGCCAAGGGCGGCGCGCCCTGGGGGTGCCCGGGGGCGCTTC TTCCCCAGGGCGTTACGCACCGGCGGCCCGGCGCGGAGGAGCTACTCTCCTCCTGGTGAG GTGGAAATTCCAGCAAGAATAGAGGTGAAGACAAGCCACCAGGACTCAGGAGGGAAACGC TGACCATTAGAAACCTCTGCATAAGACGTTGTAAGGAGGAAAATAAAAGAGAGAAAAACA CAAAGATTTAAACAAGAAACCTACGAACCCAGCTCTGGAAAGAGCCACCTTCTCCAAAAT GGATATGTTTCCTCTCACCTGGGTTTTCTTAGCCCTCTACTTTTCAAGACACCAAGTGAG AGGCCAACCAGACCCACCGTGCGGAGGTCGTTTGAATTCCAAAGATGCTGGCTATATCAC CTCTCCCGGTTACCCCCAGGACTACCCCTCCCACCAGAACTGCGAGTGGATTGTTTACGC CCCCGAACCCAACCAGAAGATTGTCCTCAACTTCAACCCTCACTTTGAAATCGAGAAGCA CGACTGCAACTTGCTGTCTGCTTGGAAAATTTCACTCACAAGCCGCAGCTTTGCCTGACT CAGTGCAATCCAAGGCCATCATCTCTGGTGAACTTCCCTTGACTCCTCCCTCCAGCCACT TGCAGAAATGCAAATCCTGGGCACCCACAGGCTGTTTGGGGGCCTGTATAGAAGCTGTGG GCAGAAACCAGAGGCCACTGTGGTACTGCTGGACTCCTGCAGCCAAAGGACAAAAGGGCG AGACTACGGGCCGTCTGGGCAAACAGAGAGAAGCCACTTTATTCCCTGTGGAGTGGAGGA TGCTAGGATGTTGCTGCTCCGGCAGACAGAGGCCTTTCGCTTGAGTCATCAGCCAACAGA CTGAATGTTATGGTTTTAGAAACCCATACACAAAGTTGAGTGGTTTTTTCCATTTCTAAA ATTTAAAATGTATGTATTTTTAAAACACCCACCTGCATGTAATACACAGCTTGTTCAGGA GTTCTCAAACAGCCCCAGCACCCACCCCATCCCAGAGGCTCAACCAAATAAAACCAAAAC CAGGAGGCTGGGTCCTTTTAAGCACTGGTAATTTCTACCTGTAATTCCAGCCCTTTGGGA GGCCGAGGCAGGCAGGTCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGTCAACATGGTG AAACCCCGTCTCTACTAAAAATACAAAAAAAATTAGCCAAGCTTGGTGGTGCGTGCCTGT AATCTCAGCTACTCTGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGCT GCAGTGAGCTGAGATTGTGCCACTGCACTCCGGCCTGGGTGAAAGAGTGAGACTCTGTCT CAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC009222 unedited NAAAAGTTTAGATTTTGTNATACGACTCCTATAGGCGGCACGCGAATTCGCACGAGGGCA GAGCATGTTTGGGACATAACAAAGGATCTGAGTAGTAAACACCGTACGCCACCCAACTCC TCTTGTAACGCCATCGCGCGTGGCATTGTGTTGGGTTCTGCGTGTGTGGCATCGGAGTCG TGGAATTTAGGGGGAACAAGGCTTTTCCCCCCGTCCCCCCGGGGTCTCCCTTGGGTGGGG GCGACACGGCCAAGGGCGGCGCGCCCTGGGGGTGCCCGGGGGCGCTTCTTCCCCAGGGCG TTACGCACCGGCGGCCCGGCGCGGAGGAGCTACTCTCCTCCTGGTGAGGTGGAAATTCCA GCAAGAATAGAGGTGAAGACAAGCCACCAGGACTCAGGAGGGAAACGCTGACCATTAGAA ACCTCTGCATAAGACGTTGTAAGGAGGAAAATAAAAGAGAGAAAAACACAAAGATTTAAA CAAGAAACCTACGAACCCAGCTCTGGAAAGAGCCACCTTCTCCAAAATGGATATGTTTCC TCTCACCTGGGTTTTCTTAGCCCTCTACTTTTCAAGACACCAAGTGAGAGGCCAACCAGA CCCACCGTGCGGAGGTCGTTTGAATTCCAAAGATGCTGGCTATATCACCTCTCCCGGTTA CCCCCAGGACTACCCCTCCCACCAGAACTGCGAGTGGATTGTTTACGCCCCCGAACCCAA CCAGAAGATTGTCCTCAACTTCAACCCTCACTTTGAAATCGAGAAGCACGACTGCAACTT GCTGTCTGCTTGGAAAATTTCACTCACAAGCCGCAGCTTTGCCTGACTCAGTGCAATCCA AGGCCATCATCTCTGGTGAACTTNCCTTGACTCCTCCCTCCAGCCACTTGCAGGAATGCA AATCCTGGGCAC
Restriction Sites	Please inquire
ACCN	BC009222
Insert Size	1500 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC009222.1, AAH09222.1
RefSeq Size	1587 bp
RefSeq ORF	300 bp
Locus ID	8828
Protein Families	Druggable Genome, Transmembrane
Gene Summary	This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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